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| 1 | HIGH PERFORMANCE ELECTRIC FIELD MICRO SENSOR WITH COMBINED DIFFERENTIAL STRUCTURE显示文摘This paper presents a high performance electric field micro sensor with combined differential structure.The sensor consists of two backward laid micro-machined chips,each packaged by polymer and metal.The novel combined differential structure effectively reduces various environmental affections,such as thermal drift,humidity drift and electrostatic charge accumulation.The sensor is tested in near-ground place as well as balloon-borne sounding.In different weather conditions,the measurement results showed good agreement with those of the commercial electric field mill. | Wen Xiaolong Peng Chunrong Fang Dongming Yang Pengfei Chen Bo Zheng Fengjie Xia Shanhong | 2014 | Journal of Electronics(China)2014，31，2： | 7 |
| 2 | Uniformly grown PtCo-modified C03O4 nanosheets as a highly efficient catalyst for sodium borohydride electrooxidation显示文摘 | Congying Song Dongming Zhang Bin Wang Zhuang Cai Peng Yan Yang Sun Ke Ye Dianxue Cao Kui Cheng Guiling Wang | 2016 | Nano Research2016，9，11： | 5 |
| 3 | Sortilin promotes macrophage cholesterol accumulation and aortic atherosclerosis through lysosomal degradation of ATP-binding cassette transporter A1 protein显示文摘Sortilin is closely associated with hyperlipidemia and the risk of atherosclerosis(AS).The role of sortilin and the underlying mechanism in peripheral macrophage are not fully understood.In this study,we investigated the effect of macrophage sortilin on ATP-binding cassette transporter A1(ABCA1)expression,ABCA1-mediated cholesterol efflux,and aortic AS.Macrophage sortilin expression was upregulated by oxidized low-density lipoproteins(ox-LDLs)in both concentration-and time-dependent manners.Its expression reached the peak level when cells were incubated with 50μg/ml ox-LDL for 24 h.Overexpression of sortilin in macrophage reduced cholesterol efflux,leading to an increase in intracellular total cholesterol,free cholesterol,and cholesterol ester.Sortilin was found to bind with ABCA1 protein and suppress macrophage ABCA1 expression,resulting in a decrease in cholesterol efflux from macrophages.The inhibitory effect of sortilin in cholesterol efflux was partially reversed by treatment with chloroquine,a lysosomal inhibitor.On the contrary,the ABCA1 protein level and ABCA1-mediated cholesterol efflux is increased by sortilin short hairpin RNA transfection.The fecal and biliary cholesterol 3H-sterol from cholesterol-laden mouse peritoneal macrophage was reduced by sortilin overexpression through lentivirus vector(LV)-sortilin in low-density lipoprotein receptor knockout mice,which was prevented by co-treatment with chloroquine.Treatment with LV-sortilin reduced plasma high-density lipoprotein and increased plasma ox-LDL levels.Accordingly,aortic lipid deposition and plaque area were exacerbated,and ABCA1 expression was reduced in mice in response to infection with LV-sortilin alone.These effects of LV-sortilin were partially reversed by chloroquine.Sortilin enhances lysosomal degradation of ABCA1 protein and suppresses ABCA1-mediated cholesterol efflux from macrophages,leading to foam cell formation and AS development. | Yuncheng Lv Jing Yang Anbo Gao Sha Sun Xilong Zheng Xi Chen Wei Wan Chaoke Tang Wei Xie Suyun Li Dongming Guo Tianhong Peng Guojun Zhao Liyuan Zhong | 2019 | Acta Biochimica et Biophysica Sinica2019，51，5： | 4 |
| 4 | Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)显示文摘Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given. | WeiPing Liu ZhiHong Li JiangJun He XiaoDong Tang Gang Lian Zhu An JianJun Chang Han Chen QingHao Chen XiongJun Chen ZhiJun Chen BaoQun Cui XianChao Du ChangBo Fu Lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou HanXiong Huang Ning Huang BaoLu Jia LiYang Jiang Shigeru Kubono JianMin Li KuoAng Li Tao Li YunJu Li Maria Lugaro XiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren YangPing Shen Jun Su LiangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu ShiWei Xu ShengQuan Yan LiTao Yang Yao Yang XiangQing Yu Qian Yue Sheng Zeng HuanYu Zhang Hui Zhang LiYong Zhang NingTao Zhang QiWei Zhang Tao Zhang XiaoPeng Zhang XueZhen Zhang ZiMing Zhang Wei Zhao Zuo Zhao Chao Zhou | 2016 | Science China(Physics,Mechanics & Astronomy)2016，59，4： | 3 |
| 5 | Behavior and mechanism of graphene oxide-tris(4-aminophenyl)amine composites in adsorption of rare earth elements显示文摘Three-dimensional(3D)graphene oxide-tris(4-aminophenyl)amine(GO-TAPAx:y)composites with different GO-to-TAPA mass ratios(x:y)were prepared by a facile one-step ultrasonic treatment.GOTAPAx:y composites were characterized by scanning electron microscopy(SEM),nitrogen(N2)adsorption-desorption isotherms,Fourier transform infrared spectroscopy(FTIR),X-ray photoelectron spectroscopy(XPS)and thermogravimetric analysis(TGA).Behavior and mechanism of GO-TAPAx:yco mposites for the adsorption of rare earth elements(REEs)were investigated.The adso rption capacities of GO-TAPA1;2 composite for Yb^3+,Er^3+,Nd^3+,La^3+and Y^3+are 30.88,26.52,20.60,11.24 and 10.52 mg/g,respectively.Effects of some important parameters including GO-to-TAPA mass ratios,contact time,reaction temperature and initial Yb^3+concentration on the adsorption were evaluated in detail.FTIR spectral and XPS analyses show that the metal complexations and ion exchanges between nitrogen/oxygen-containing species of the adsorbents and REEs are involved in the adsorption procedure besides the conventional adsorption based on specific surface area,indicating the introduction of specific molecules onto GO is beneficial to its adsorption ability.The convenient reusability and applicability of GO-TAPAx:y composites toward real samples also demonstrate their feasibility in the enrichment of REE ions. | Xiaoru Zhao Xinyu Jiang Dongming Peng Jie Teng Jingang Yu | 2021 | Journal of Rare Earths2021，39，1： | 3 |
| 6 | Crystal structure of the African swine fever virus structural protein p35 reveals its role for core shell assembly显示文摘Dear Editor,The African swine fever(ASF)is a highly contagious hemorrhagic and lethal disease in domestic pigs.The ASF outbreaks of in many Asia countries,including China,Vietnam,Mongolia,and South Korea,have posed a huge threat to the pig indusry.In the attempt to stop ASF from spreading further in China's Mainland,more than 10 million pigs have been culled since August 2018.The causative agent for ASF is a DNA virus,African swine fever virus(ASFV).Although this deadly disease has been reported in Kenya nearly one hundred years ago,there has been no vaccine for protection from ASFV infection or effective treatments to cure ASF until now. | Guobang Li Dan Fu Guangshun Zhang Dongming Zhao Mingyu Li Xue Geng Dongdong Sun Yuhui Wang Cheng Chen Peng Jiao Lin Cao Yu Guo Zihe Rao | 2020 | Protein & Cell2020，11，8： | 3 |
| 7 | Structure of African swine fever virus p15 reveals its dual role for membrane-association and DNA binding显示文摘Dear Editor, African swine fever (ASF) is a highly contagious disease of domestic pigs caused by African swine fever virus (ASFV),with mortality rates approaching 90%-100%.The first ASF case was described in 1921 in Kenya.Over the past decades, ASF has spread from Sub-Saharan Africa to Europe and Asia, and pose a huge threat to global food safety.Since the first ASF case reported in August 2018, more than 10 million pigs had been culled in China at an enormous economic loss.The risk of ASFV mutating to infect humans is extremely low.However, ASF not only threatens food security but also severely strikes the world economy in many fields, such as the global supply of the blood thinner heparin,most of which is produced from pigs.Hence, ASF is a strictly monitored infectious animal disease by OIE (World Organization for Animal Health), unfortunately, there is no approved drug or vaccine against this lethal viral disease. | Dan Fu Dongming Zhao Wei Zhang Guangshun Zhang Mingyu Li Zheng Zhang Yuhui Wang Dongdong Sun Peng Jiao Cheng Chen Yu Guo Zihe Rao | 2020 | Protein & Cell2020，11，8： | 3 |
| 8 | High-stability electrostatic field micro sensor for sounding thunderstorm applications显示文摘In this paper,the design and experimental results for a novel high-stability sounding electrostatic field micro sensor are presented.By means of hermetic chip sealing,digital weak signal demodulation unit,and probe sensor structure design,harsh environmental adaptation problems such as low temperature,high humidity,low air pressure,waterfall are solved.The sensor has a high resolution of 14 V/m,a wide measurement range of±100 kV/m,and is proved to have superior stability and performance in sounding electric field experiments than traditional sensors under different kinds of weather. | WEN Xiaolong PENG Chunrong FANG Dongming YANG Pengfei REN Tianling XIA Shanhong | 2014 | Instrumentation2014，1，3： | 3 |
| 9 | SSD Real-Time Illegal Parking Detection Based on Contextual Information Transmission显示文摘With the improvement of the national economic level,the number of vehicles is still increasing year by year.According to the statistics of National Bureau of Statics,the number is approximately up to 327 million in China by the end of 2018,which makes urban traffic pressure continues to rise so that the negative impact of urban traffic order is growing.Illegal parking-the common problem in the field of transportation security is urgent to be solved and traditional methods to address it are mainly based on ground loop and manual supervision,which may miss detection and cost much manpower.Due to the rapidly developing deep learning sweeping the world in recent years,object detection methods relying on background segmentation cannot meet the requirements of complex and various scenes on speed and precision.Thus,an improved Single Shot MultiBox Detector(SSD)based on deep learning is proposed in our study,we introduce attention mechanism by spatial transformer module which gives neural networks the ability to actively spatially transform feature maps and add contextual information transmission in specified layer.Finally,we found out the best connection layer in the detection model by repeated experiments especially for small objects and increased the precision by 1.5%than the baseline SSD without extra training cost.Meanwhile,we designed an illegal parking vehicle detection method by the improved SSD,reaching a high precision up to 97.3%and achieving a speed of 40FPS,superior to most of vehicle detection methods,will make contributions to relieving the negative impact of illegal parking. | Huanrong Tang Aoming Peng Dongming Zhang Tianming Liu Jianquan Ouyang | 2020 | Computers, Materials & Continua2020，，1： | 2 |
| 10 | Tumor microenvironment responsive drug delivery systems显示文摘Conventional tumor-targeted drug delivery systems(DDSs)face challenges,such as unsatisfied systemic circulation,low targeting efficiency,poor tumoral penetration,and uncontrolled drug release.Recently,tumor cellular molecules-triggered DDSs have aroused great interests in addressing such dilemmas.With the introduction of several additional functionalities,the properties of these smart DDSs including size,surface charge and ligand exposure can response to different tumor microenvironments for a more efficient tumor targeting,and eventually achieve desired drug release for an optimized therapeutic efficiency.This review highlights the recent research progresses on smart tumor environment responsive drug delivery systems for targeted drug delivery.Dynamic targeting strategies and functional moieties sensitive to a variety of tumor cellular stimuli,including pH,glutathione,adenosine-triphosphate,reactive oxygen species,enzyme and inflammatory factors are summarized.Special emphasis of this review is placed on their responsive mechanisms,drug loading models,drawbacks and merits.Several typical multi-stimuli responsive DDSs are listed.And the main challenges and potential future development are discussed. | Qunye He Jun Chen Jianhua Yan Shundong Cai Hongjie Xiong Yanfei Liu Dongming Peng Miao Mo Zhenbao Liu | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，4： | 2 |
| 11 | Synthesis, Characterization and Hydrolysis of an Aliphatic Polycarbonate by Terpolymerization of Carbon Dioxide, Propylene Oxide and Maleic Anhydride显示文摘 | Liu Yanfei Huang Kelong Peng Dongming | 2006 | Polymer2006，47，： | 1 |
| 12 | A New Type of CMOS Temperature Sensor显示文摘 | Zhang Xun Wang Peng Jin Dongming | 2005 | Chinese Journal of Semicondutors2005，26，11： | 1 |
| 13 | Design, fabrication and application of an SOI-based resonant electric field microsensor with coplanar comb-shaped electrodes显示文摘 | YANG Pengfei PENG Chunrong FANG Dongming | 2013 | Journal of Micromechanics and Microengineering2013，23，055： | 1 |
| 14 | Synthesis, characterization and hydrolysis of an aliphatic polycarbonate by terpolymedzation of carbon dioxide, propylene oxide and maleie anhydride显示文摘 | LIU Yanfei HUANG Kelong PENG Dongming | 2006 | Polymer2006，47，26： | 1 |
| 15 | Preparation of carbon dioxide/propylene oxide/s-eaprolactone copolymers and their drug release behaviors显示文摘 | PENG Dongming HUANG Kelong LIU Yanfei | 2007 | Polymer Bulletin2007，59，： | 1 |
| 16 | Preparation of poly(butylene-eo-e-caprolaetone carbonate) and their use as drug carriers for a controlled delivery显示文摘 | LIU Yanfei HUANG Kelong PENG Dongming | 2007 | Journal of Polymer Science Part A: Polymer Chemistry2007，45，11： | 1 |
| 17 | Preparation of carbon dioxide/propylene oxide/ε-caprolactone copolymers and their drug release behaviors显示文摘 | PENG Dongming HUANG Kelong LIU Yanfei | 2007 | Polym Bull2007，59，： | 1 |
| 18 | Synthesis,characterization and hydrolysis of an aliphatic polycarbonate by terpolymerization of carbon dioxide,propylene oxide and maleic anhydride显示文摘 | LIU Yanfei HUANG Kelong PENG Dongming | 2006 | Ploymer2006，47，： | 1 |
| 19 | Time-Domain Full Waveform Inversion Using the Gradient Preconditioning Based on Transmitted Wave Energy显示文摘The gradient preconditioning approach based on seismic wave energy can effectively avoid the huge memory consumption of the gradient preconditioning algorithms based on the Hessian matrix. However, the accuracy of this approach is prone to be influ- enced by the energy of reflected waves. To tackle this problem, the paper proposes a new gradient preconditioning method based on the energy of transmitted waves. The approach scales the gradient through a precondition factor, which is calculated by the ‘ap- proximate transmission wavefield’ simulation based on the nonreflecting acoustic wave equation. The method requires no computing nor storing of the Hessian matrix and its inverse matrix. Furthermore, the proposed method can effectively eliminate the effects of geometric spreading and disproportionality in the gradient illumination. The results of model experiments show that the time-domain full waveform inversion (FWI) using the gradient preconditioning based on transmitted wave energy can achieve higher inversion accuracy for deep high-velocity bodies and their underlying strata in comparison with the one using the gradient preconditioning based on seismic wave energy. The field marine seismic data test shows that our proposed method is also highly applicable to the FWI of field marine seismic data. | SONG Peng TAN Jun LIU Zhaolun ZHANG Xiaobo LIU Baohua YU Kaiben LI Jinshan XIA Dongming XIE Chuang | 2019 | Journal of Ocean University of China2019，18，4： | 1 |
| 20 | Preparation of poly(butylene-co-ε-caprolactone carbonate) and their use as drug carriers for a controlled delivery system显示文摘 | Liu Yanfei Huang Kelong Peng Dongming | 2007 | Journal of Polymer Science: Part A2007，45，11： | 1 |
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