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16篇 您的检索式:作者名="Olijslagers"
    题名 作者 年代 出处 被引量
1Epigenetic inactivation of the human sprouty2 ( hSPRY2 ) homologue in prostate cancer 显示文摘Mckie AB Douglas DA Olijslagers S 2005Oncogene2005,24,13:1
2Potentiation of a recombinant oncolytic parvovirus by expression of Apoptin显示文摘 Dege A Y Dinsart C 2001Cancer Gene Ther2001,8,12:1
3Rapid changes in hippocampal CA1 pyramidal cell function via pre- as well as postsynaptic membrane mineralocorticoid receptors 显示文摘Olijslagers J E de-Kloet E R Elgersma Y 2008Eur J Neurosci2008,27,10:1
4Additive cytotoxic effect of apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumour cells显示文摘Olijslagers SJ Zhang YH Backendorf C 0,,02:1
5Apoptin特写:新治疗展望(英文)显示文摘Apoptin诱导人转化细胞而不是正常细胞的凋亡,特异性地感知转化细胞的信号并被激活。这些特性使得Apoptin成为一种用于与细胞转化相关的肿瘤以及自身免疫性疾病(如风湿性关节炎)的前景型制剂。不同研究小组相继报道了细胞转化特异性过程和Apoptin凋亡诱导的相关性,如肿瘤特异激酶激活以及p53阴性转化细胞中细胞分裂后期启动复合物(APC)即起关键作用。体内外前临床基因治疗研究和蛋白转导试验充分显示Apoptin作为治疗制剂的有效性和安全性。化疗药物,如etoposide、paclitaxel或methotrexate(甲氨蝶呤)与Apoptin的联合治疗,协同增强了对肿瘤细胞的毒效应。对Apoptin感知的细胞转化信号通路的深入研究,将有助于在分子水平上进一步揭示癌发生或风湿性关节炎疾病的病理机制。Apoptin工艺与其它化疗制剂的结合,将为细胞转化相关疾病提供新颖的治疗策略。章应慧 Sharon J Olijslagers Claude Backendorf Mathieu HM Noteborn 2006医学分子生物学杂志2006,3,6:1
6Additive cytotoxic effect of Apoptin and chemotherapeutic agents paditaxel and etoposide on human tumour cells显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Cain Pharmacol Toxicol2007,100,2:1
7Additive cytotoxic effect of apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumour cells显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Clin Pharmacol Toxicol2007,100,2:1
8Modulation of midbrain dopamine neurotransmission by serotonin,a versatile interaction between neurotransmitters and significance for antipsychotic drug action显示文摘Olijslagers JE Werkman TR McCreary AC 2006Curr Neuropharmacol2006,4,1:1
9Modulation of midbrain dopamine neurotransmission by serotonin,a versatile interaction between neurotransmitters and significance for antipsychotic drug action显示文摘Olijslagers JE Werkman TR McCreary AC 0,,:1
10Biodegradable hollow fibers for the controlled release of hormones 显示文摘EennilM J D Olijslager J Albers J H M 1987Control Release1987,6,22:1
11Additive cytotoxic effect of apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumor cells显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Clin Phannaeol Toxieol2007,100,2:1
12Additive cytotoxic effect of apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumour cells显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Clin Pharmacol Toxicol2007,100,2:1
13Additive cytotoxic effect of apeptin and chemotherapeutic agents paclitaxel and etopeside on human tumour cells 显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Clin Pharmacol Toxicol2007,100,2:1
14Additive cytotoxic effect of Apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumour cells显示文摘Olijslagers SJ Zhang YH Backendorf C 2007Basic Clin Pharmacol Toxicol2007,100,2:1
15Mitochondrial dys function is a possible cause of accelerated senescence of meso thelial cells exposed to high glucose显示文摘Ksiazek K Passos JF Olijslagers S 2001Kidney Int2001,59,2:1
16Additive cytotoxiceffect of apoptin and chemotherapeutic agents paclitaxel andetoposide on human tumour cells 显示文摘Olijslagers S J Zhang Y H Backendorf C 2007Basic Clin PharmacolToxicol2007,100,2:1
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