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| 1 | H e l i c o b a c t e r p y l o r iinfection and the development ofgastric cancer显示文摘 | U e m u r a N O k a m o t o S Y a m a m o t oS e t a l | 2001 | N Engl J Med2001，345，11： | 1 |
| 2 | Liver stiffness predicts clinical outcome in human immunodeficiency virus/hepatitis C virus‐coinfected patients with compensated liver cirrhosis显示文摘 | Nicolás Merchante Antonio Rivero‐Juárez Francisco Téllez Dolores Merino Maria José Ríos‐Villegas Manuel Márquez‐Solero Mohamed Omar Juan Macías ángela Camacho Montserrat Pérez‐Pérez Jesús Gómez‐Mateos Antonio Rivero Juan Antonio Pineda | 2012 | Hepatology2012，，1： | 1 |
| 3 | Therapy- induced toxicity of the lungs: an overview 显示文摘 | Cbarpidou AG Gk ioz os I T sim poukis S | 2009 | Ant icancer Res2009，29，2： | 1 |
| 4 | Anti-Ramsey theorems显示文摘 | ERDO¨S P SIMONOVITS M S’OS V T | 1985 | Graphs and Combinatorics1985，1，1： | 1 |
| 5 | Role of p38 MAP kinase in regulation of cell migration and proliferation in healing corneal epithelium显示文摘 | Saika S Okada Y Miyamoto T Yamanaka OS Ohnishi YO Oshima AK | 2004 | Invest Ophthalmol Vis Sci2004，45，： | 1 |
| 6 | Granulocyte colony-stimu-lating factor impendes recovery from damage caused by cytotoxic a-gents through increased differentiation at the expensed self-renewal显示文摘 | Van Os R Robinson S Sheridan T | 2000 | Stem Cells2000，18，： | 1 |
| 7 | Granulocyte colony-stimu-lating factor impendes reco very fromdamage caused by cytotoxic a- gents through increased differentiation at the expens ed self-renewal显示文摘 | Van Os R Robinson S Sheridan T et a1 | | 0，，： | 1 |
| 8 | Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis :A randomized controlled trial显示文摘 | Agodoa LY Appel L Bakris GL Beck G Bourgoignie J Briggs JP Charleston J Cheek D Cleveland W Douglas JG Douglas M Dowie D Faulkner M Gabriel A Gassman J Greene T Hall Y Hebert L Hiremath L Jamerson K Johnson CJ Kopple J Kusek J Lash J Lea J Lewis JB Lipkowitz M Massry S Middleton J Miller ER 3rd Norris K O'Connor D Ojo A Phillips RA Pogue V Rahman M Randall OS Rostand S Schulman G Smith W Thornley-Brown D Tisher CC Toto RD Wright JT Jr Xu S African American Study of Kidney Disease and Hypertension (AASK) Study Group | 2001 | JAMA2001，285，21： | 1 |
| 9 | Granulocyte -colony stimulating factor impedes recovery from damage caused bycytotoxic agents through increased differentiation at the expense ofself - renewal显示文摘 | VAN OS R ROBINSON S SHERIDAN T | 2000 | Stem Cells2000，18，2： | 1 |
| 10 | Granulocyte colony- stimulating factor impendes recovery from damage caused by cytotoxic agents through increased differentiation at the expensed self - renewal 显示文摘 | Van Os R Robinson S Sheridan T | 2000 | Stem Cells2000，18，： | 1 |
| 11 | Thermal conductivity of W-Cu composites at various temperatures显示文摘 | KIM Y D OH N L OS S T | 2001 | Materials Letters2001，51，5： | 1 |
| 12 | Granulocyte colony-stimu-lating factor enhances bone marrow stem cell damag caused by repeated administration of cytotoxic agents显示文摘 | Van Os R Robinson S Sheridan T | 1998 | Blood1998，92，： | 1 |
| 13 | Granulocyte colonystimulating factor impedes recovery from damage caused by cytotoxic agents through increased differentiation at the expense of self-renewal显示文摘 | Van Os R Robinson S Sheridan T | 2000 | Stem Cells2000，18，： | 1 |
| 14 | Abscessed pneumonia with abscess secondary to infected mediastinic teratoma显示文摘 | MILLN GUILARTE M T OSS MUNRRIZ M I GARCA GARAYOA J M | 2011 | Med Intensiva2011，35，： | 1 |
| 15 | Vision and development in Trichoderma atroviride显示文摘Phototropism, the induction of carotenogenesis and reproductive structures, and resetting of the circadian rhythm are controlled by blue light. Trichoderma is used as a photomorphogenetic model due to its ability to conidiate upon exposure to light. In total darkness, T. atroviride grows indefinitely as a mycelium provided that nutrients are not limiting. However, nutrient deprivation and light trigger the conidiation process. A pulse of blue light given to a radially growing colony induces synchronous sporulation. A ring of conidiophores bearing green conidia is produced at what had been the colony perimeter at the time of the light pulse. All known responses to blue light in N. crassa are initiated by a couple of transcription factors encoded by the white-collar genes (wc -1 and wc-2). WC-1 and WC-2 bind to the promoters of light regulated genes to rapidly activate transcription in response to light. In T. atroviride the photolyase encoding gene phr1 undergoes fast transcriptional activation in response to light. The presence of putative WCC binding boxes in the promoter of phr1, suggested that light responses in Trichoderma could be under the control of white-collar homologues. We cloned two genes and demonstrated by gene replacement that both are essential for photoconidiation and photolyase gene expression. Therefore, they were named blue-light regulator one and two (blr1 and blr2). The BLR1 protein has all the characteristics of a blue-light photoreceptor. The generation of subtractive cDNA libraries allowed us to identify novel, BLR independent, light responses including the regulation of gene expression by blue-light. In addition, we recently initiated a Trichoderma ESTs sequencing project. Until now, we have sequenced above 3000 ESTs, from which we have obtained approximately 1800 unigenes. This unigene set was printed in microarrays and used to search for light induced genes. Twenty five clearly induced and around thirty repressed genes have been detected. Among this set we have found both blr dependent and independent blue light induced genes, strengthening our view of the existence of alternative light perception pathways. We also show the first evidence for the entry of Trichoderma into the conidiation process caused by mechanical injury, which remains unaltered in the mutants. Finally, an unprecedented crosstalk between light and glucose sensing was found involving the BLR1 and BLR2 proteins in the control of carbon deprivation induced conidiation. | Casas S Cortés C Ríos M Rosales T Bibbins M Olmedo V Herrera-Estrella A | 2004 | 浙江大学学报(农业与生命科学版)2004，30，4： | 0 |
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