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| 1 | 前庭性偏头痛:诊断标准——Barany学会及国际头痛学会共识文件显示文摘本文提供了前庭性偏头痛的诊断标准,由Barany学会前庭疾患分类委员会及国际头痛学会(IHS)偏头痛分类分委员会共同制定。分类包括前庭性偏头痛及很可能的前庭性偏头痛。与IHS的常规程序相同,前庭性偏头痛作为一种新分类,将首先出现在第3版国际头痛分类(ICHD-3)的附录中。若积累了进一步的证据,很可能的前庭性偏头痛也许会纳入更晚的ICHD版本中。前庭性偏头痛的诊断建立在反复发作的前庭症状、具有偏头痛病史、前庭症状与偏头痛症状间存在时间上的相关性,并排除其他可导致前庭症状的病因。符合前庭性偏头痛诊断的症状包括不同类型的眩晕及头部活动诱发的头晕伴恶心。症状的严重程度必须为中重度。急性发作的持续时间限于5 min^72 h的时间窗内。 | 华驾略 李焰生 Lempert T Olesen J Furman J Waterston J Seemungal B Carey J Bisdorff A Versino M Evers S Newman-Toker D | 2013 | 神经病学与神经康复学杂志2013，10，3： | 60 |
| 2 | Systematic mechanism-orientated approach to chronic pancreatitis pain显示文摘Pain in chronic pancreatitis(CP) shows similarities with other visceral pain syndromes(i.e.,inflammatory bowel disease and esophagitis),which should thus be managed in a similar fashion.Typical causes of CP pain include increased intrapancreatic pressure,pancreatic inflammation and pancreatic/extrapancreatic complications.Unfortunately,CP pain continues to be a major clinical challenge.It is recognized that ongoing pain may induce altered central pain processing,e.g.,central sensitization or pro-nociceptive pain modulation.When this is present conventional pain treatment targeting the nociceptive focus,e.g.,opioid analgesia or surgical/endoscopic intervention,often fails even if technically successful.If central nervous system pain processing is altered,specific treatment targeting these changes should be instituted(e.g.,gabapentinoids,ketamine or tricyclic antidepressants).Suitable tools are now available to make altered central processing visible,including quantitative sensory testing,electroencephalograpy and(functional) magnetic resonance imaging.These techniques are potentially clinically useful diagnostic tools to analyze central pain processing and thus define optimum management approaches for pain in CP and other visceral pain syndromes.The present review proposes a systematic mechanism-orientated approach to pain management in CP based on a holistic view of the mechanisms involved.Future research should address the circumstances under which central nervous system pain processing changes in CP,and how this is influenced by ongoing nociceptive input and therapies.Thus we hope to predict which patients are at risk for developing chronic pain or not responding to therapy,leading to improved treatment of chronic pain in CP and other visceral pain disorders. | Stefan AW Bouwense Marjan de Vries Luuk TW Schreuder Soren S Olesen Jens B Frokjær Asbjorn M Drewes Harry van Goor Oliver HG Wilder-Smith | 2015 | World Journal of Gastroenterology2015，21，1： | 6 |
| 3 | Pharmacological challenges in chronic pancreatitis显示文摘Drug absorption in patients with chronic pancreatitis might be affected by the pathophysiology of the disease.The exocrine pancreatic insufficiency is associated with changes in gastrointestinal intraluminal pH,motility disorder,bacterial overgrowth and changed pancreatic gland secretion.Together these factors can result in malabsorption and may also affect the efficacy of pharmacological intervention.The lifestyle of chronic pancreatitis patients may also contribute to gastrointestinal changes.Many patients limit their food intake because of the pain caused by eating and in some cases food intake is more or less substituted with alcohol,tobacco and coffee.Alcohol and drug interaction are known to influence the pharmacokinetics by altering either drug absorption or by affecting liver metabolism.Since patients suffering from chronic pancreatitis experience severe pain,opioids are often prescribed as pain treatment.Opioids have intrinsic effects on gastrointestinal motility and hence can modify the absorption of other drugs taken at the same time.Furthermore,the increased fluid absorption caused by opioids will decrease water available for drug dissolution and may hereby affect absorption of the drug.As stated above many factors can influence drug absorption and metabolism in patients with chronic pancreatitis.The factors may not have clinical relevance,but may explain inter-individual variations in responses to a given drug,in patients with chronic pancreatitis. | Anne Estrup Olesen Anne Brokjaer Iben WD Fisher Isabelle M Larsen | 2013 | World Journal of Gastroenterology2013，19，42： | 3 |
| 4 | 年龄和靶器官损害对24h动态血压预后价值的影响显示文摘靶器官损害标志物和测量24h动态血压可以改善心血管风险分层。随着年龄的增长,靶器官损害和血压升高的发病率增加。该研究目的是评估年龄和靶器官损害对动态血压预测预后价值的影响。 | 黄洁 叶鹏 Olesen TB Stidsen JV Blicher MK Pareek M Rasmussen S Vishram-Nielsen JKK Olsen MH | 2017 | 中华高血压杂志2017，25，10： | 2 |
| 5 | PACAP-38 but not VIP induces release of CGRP from trigeminal nucleus caudalis via a receptor distinct from the PAC1 receptor显示文摘 | Olesen IJ Baun M Dipak V | 2014 | Neuropeptides2014，48，： | 1 |
| 6 | Specific, semi-quantitative detection of the soybean allergen Gly m Bd 30K DNA by PCR显示文摘 | TORP A M OLESEN A STEN E | 2006 | Food Control2006，17，5： | 1 |
| 7 | Oral anticoagu lation and antiplatelets in atrial fibrillation patients after myo cardial infarction and coronary intervention 显示文摘 | Lamberts M Gislason G H Olesen J B | 2013 | J Am Coll Cardiol2013，62，11： | 1 |
| 8 | Consequences of climate change for European agri- cultural productivity, land use and policy显示文摘 | Olesen J Bindib M | 2002 | European Journal of A- gronomy2002，16，4： | 1 |
| 9 | Short-term strength training and the expression of myostatin and IGF-Ⅰ isoforms in rat muscle and tendon: differential effects of specific contraction types 显示文摘 | HEINEMEIER K M OLESEN J L SCHJERLING P | 2007 | J Appl Physiol2007，102，2： | 1 |
| 10 | Temporal changes in pollen flow and neighbourhood structure in a population of Saxifraga birculus L显示文摘 | OLESEN J M WARNCKE E | 1989 | Oeco/o^''a1989，79，2： | 1 |
| 11 | The economic cost of brain disorders in Europe显示文摘 | Olesen J Gustavsson A Svensson M | 2012 | Eur J Neurol2012，19，1： | 1 |
| 12 | Short-term strength training and the expression of myostatin and IGF-Ⅰ isoforms in rat muscle and tendon: differential effects of specific contraction types 显示文摘 | Heinemeier K M Olesen J L Schjerling P | 2007 | J Appl Physiol2007，102，2： | 1 |
| 13 | Land sur-face temperature and emissivity estimation from passive sen-sor data:Theory and practice-current trends显示文摘 | DASH P GOTTSCHE F M OLESEN F S | 2002 | InternationalJournal of Remote Sensing2002，23，13： | 1 |
| 14 | No influence of OPG and its ligands, RANKL and TRAIL, on proliferation and regulation of the calcification process in primary hu- man vascular smooth muscle cells 显示文摘 | OLESEN M SKOV V MECHTA M | 2012 | Mol Cell Endocri- nol2012，362，12： | 1 |
| 15 | The industrial dy-namics of open innovation-Evidence from the transformation of con-sumer electronics 显示文摘 | CHRISTENSEN J F OLESEN M Hf KJ^R J S | 2005 | Research Policy2005，34，10： | 1 |
| 16 | Fluoxetine reverts chronic restraint stress-induced depression- like behaviour and increases neuropeptide Y and galanin expression in mice 显示文摘 | Christiansen S H Olesen M V Worewein G | 2011 | Behav Brain Res2011，216，2： | 1 |
| 17 | WT1 gene expression : An excellent tool for monitoring minimal residual disease in 70% of acute myeloid leukemia patients - results from a single - centre study显示文摘 | Ostergaard M Olesen LH Hasle H | 2004 | Br J Haeraatol2004，125，5： | 1 |
| 18 | Validation and clinical implication of aquantitative real-time PCR determination of MDRI gene expression:comparison with semiquantitative PCR in 101 patients with acute myeloid leukemia显示文摘 | OLESEN L H NORGAARD J M PALLISGAARD N | 2003 | Eur J Haematol2003，70，5： | 1 |
| 19 | Focal hyperemia followed by spreading oligemia and impaired activation of rCBF in classic migraine显示文摘 | Olesen J Larsen B Lauritzen M | | 0，，： | 1 |
| 20 | The KCNQI potassium channel: from gene to physiological function 显示文摘 | Jespersen T Grunnet M Olesen SP | 2005 | Physiology ( Bethesda )2005，20，： | 1 |
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