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| 1 | Closure of a persistent sphincterotomy-related duodenal perforation by placement of a covered self-expandable metallic biliary stent显示文摘Retroperitoneal duodenal perforation as a result of endoscopic biliary sphincterotomy is a rare complication, but it is associated with a relatively high mortality risk, if left untreated. Recently, several endoscopic techniques have been described to close a variety of perforations. In this case report, we describe the closure of a persistent sphincterotomy-related duodenal perforation by using a covered self-expandable metallic biliary (CEMB) stent. A 61-year-old Greek woman underwent an endoscopic retrograde cholangiopancreatography (ERCP) and sphincterotomy for suspected choledo-cholithiasis, and a retroperitoneal duodenal perforation (sphincterotomy-related) occurred. Despite initial conservative management, the patient underwent a laparotomy and drainage of the retroperitoneal space. After that, a high volume duodenal fistula developed. Six weeks after the initial ERCP, the patient underwent a repeat endoscopy and placement of a CEMB stent with an indwelling nasobiliary drain. The fistula healed completely and the stent was removed two weeks later. We suggest the transient use of CEMB stents for the closure of sphincterotomy-related duodenal perforations. They can be placed either during the initial ERCP or even later if there is radiographic or clinical evidence that the leakage persists. | Antonios Vezakis Georgios Fragulidis Constantinos Nastos Anneza Yallourou Andreas Polydorou Dionisios Voros | 2011 | World Journal of Gastroenterology2011，17，40： | 11 |
| 2 | Percutaneous electrochemotherapy in the treatment of portal vein tumor thrombosis at hepatic hilum in patients with hepatocellular carcinoma in cirrhosis: A feasibility study显示文摘AIM To treated with electrochemotherapy(ECT) a prospective case series of patients with liver cirrhosis and Vp3-Vp4- portal vein tumor thrombus(PVTT) from hepatocellular carcinoma(HCC), in order to evaluate the feasibility, safety and efficacy of this new non thermal ablative technique in those patients. METHODS Six patients(5 males and 1 female), aged 61-85 years(mean age, 70 years), four in Child-Pugh A and two in Child-Pugh B class, entered our study series. All patients were studied with three-phase computed tomography(CT), contrast enhanced ultrasound(CEUS) and ultrasound-guided percutaneous biopsy of the thrombus before ECT. All patients underwent ECT treatment(Cliniporator Vitae?, IGEA Sp A, Carpi, Modena, Italy) of Vp3-Vp4 PVTT in a single session. At the end of the procedure a post-treatment biopsy of the thrombus was performed. Scheduled follow-up in all patients entailed: CEUS within 24 h after treatment; triphasic contrastenhanced CT and CEUS at 3 mo after treatment and every six months thereafter.RESULTS Post-treatment CEUS showed complete absence of enhancement of the treated thrombus in all cases. Post-treatment biopsy showed apoptosis and necrosis of tumor cells in all cases. The follow-up ranged from 9 to 20 mo(median, 14 mo). In 2 patients, the followup CT and CEUS demonstrated complete patency of the treated portal vein. Other 3 patients showed a persistent avascular non-tumoral shrinked thrombus at CEUS and CT during follow-up. No local recurrence was observed at follow-up CT and CEUS in 5/6 patients. One patient was lost to follow-up because of death from gastrointestinal hemorrage 5 wk after ECT. CONCLUSION In patients with cirrhosis, ECT seems effective and safe for curative treatment of Vp3-Vp4 PVTT from HCC. | Luciano Tarantino Giuseppina Busto Aurelio Nasto Raffaele Fristachi Luigi Cacace Maria Talamo Catello Accardo Sara Bortone Paolo Gallo Paolo Tarantino Riccardo Aurelio Nasto Matteo Nicola Dario Di Minno Pasquale Ambrosino | 2017 | World Journal of Gastroenterology2017，23，5： | 7 |
| 3 | Global Consequences of Liver Ischemia/Reperfusion Injury显示文摘 | Constantinos Nastos Konstantinos Kalimeris Nikolaos Papoutsidakis Marios-Konstantinos Tasoulis Panagis M. Lykoudis Kassiani Theodoraki Despoina Nastou Vassilios Smyrniotis Nikolaos Arkadopoulos Mengzhou Xue | 2014 | Oxidative Medicine and Cellular Longevity2014，，： | 3 |
| 4 | Hepatitis B surface antigen: Relation to hepatitis B replication parameters in HBeAg-negative chronic hepatitis B显示文摘 | Emanuel K. Manesis George V. Papatheodoridis Dina G. Tiniakos Emilia S. Hadziyannis Olga P. Agelopoulou Thalia Syminelaki Christos Papaioannou Theodoros Nastos Peter Karayiannis | 2010 | Journal of Hepatology2010，，1： | 2 |
| 5 | Outdoor particulate matter and childhood asthma admissions in Athens,Greece:a time- series study显示文摘 | Nastos PT Paliatsos AG Anthracopoulos MB | 2010 | Environ Health2010，45，： | 1 |
| 6 | Acute effects of air pollution on pediatric asthma exacerbation:evidence of association and effect modification显示文摘 | Samoli E Nastos PT Paliatsos AG | 2011 | Environ Res2011，111，3： | 1 |
| 7 | Genotoxic stress ac- celerates age-associated degenerative changes in interverte- bral discs显示文摘 | Nasto LA Wang D Rnson AR | 2013 | Mech Ageing Dev2013，134，12： | 1 |
| 8 | Small liver remnants are more vulnerable to ischemia/reperfusion injury after extended hepatectomies: a case-control study显示文摘 | Theodoraki K Arkadopoulos N Nastos C | 2012 | World J Surg2012，36，12： | 1 |
| 9 | Spine degeneration in a murine model of chronic human tobacco smokers 显示文摘 | Wang D Nasto LA Roughley P | 2012 | Osteoarthfitis Cartilage2012，20，8： | 1 |
| 10 | The neuroimmune hypothesis in Parkinson's disease显示文摘 | Kuhn W Muller T Nastos I | 1997 | Rev Neurosci1997，8，： | 1 |
| 11 | Clinical predictors of vertebralosteoporotic fractures in post-menopausal women:a cross-sectionalanalysis显示文摘 | Nasto LA Fusco A Colangelo D | 2012 | Eur Rev Med Pharmacol Sci2012，16，9： | 1 |
| 12 | Surgical treatment of tuberculous spondylodiscitis显示文摘 | Pola E Rossi B Nasto LA | 2012 | Eur Rev Med Pharmacol Sci2012，16，2： | 1 |
| 13 | Development of a porcine model of post-hepatectomy liver failure显示文摘 | Arkadopoulos N Defterevos G Nastos C | 2011 | Journal of Surgical Research2011，170，2： | 1 |
| 14 | Investigating the role of -induced spine degeneration显示文摘 | Nasto LA Ngo K Leme AS et DNA damage in tobacco smoking al | 2014 | Spine J2014，14，3： | 1 |
| 15 | Genotoxic stress accelerates age-associated degenerative changes in inter- vertebral discs显示文摘 | Nasto LA Wang D Robinson AR | 2013 | Mech ageing dev2013，134，12： | 1 |
| 16 | Time trendsin pediatric hospitalizations for varicella infection are associated with climatic changes: a 22-year retrospective study in a tertiary Greek re- ferral center显示文摘 | CRITSELIS E NASTOS P THEODORIDOU K | 2012 | PLoS ONE2012，7，52： | 1 |
| 17 | ISSLS Prize Winner: Inhibition of NF-κB Activity Ameliorates Age-Associated Disc Degeneration in a Mouse Model of Accelerated Aging显示文摘 | Luigi A. Nasto Hyoung-Yeon Seo Andria R. Robinson Jeremy S. Tilstra Cheryl L. Clauson Gwendolyn A. Sowa Kevin Ngo Qing Dong Enrico Pola Joon Y. Lee Laura J. Niedernhofer James D. Kang Paul D. Robbins Nam V. Vo | 2012 | Spine2012，，21： | 1 |
| 18 | Climate variability and urbanization in Athens显示文摘 | Philandras C M Metaxas D A Nastos P T | 1999 | Theoretical and Applied Climatology1999，63，： | 1 |
| 19 | Investigating the role of DNA damage in tobacco smoking-induced spine degeneration显示文摘 | Luigi A. Nasto Kevin Ngo Adriana S. Leme Andria R. Robinson Qing Dong Peter Roughley Arvydas Usas Gwendolyn A. Sowa Enrico Pola James Kang Laura J. Niedernhofer Steven Shapiro Nam V. Vo | 2013 | The Spine Journal2013，，： | 1 |
| 20 | Mitochondrial-derived reactive oxygen species (ROS) Play a causal role in aging-related intervertebral disc degeneration 显示文摘 | Nasto LA Robinson AR Ngo K | 2013 | J Orthop Res2013，31，7： | 1 |
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