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| 1 | Chronic kidney disease severely deteriorates the outcome of gastrointestinal bleeding: A meta-analysis显示文摘AIM To understand the influence of chronic kidney disease(CKD) on mortality, need for transfusion and rebleeding in gastrointestinal(GI) bleeding patients.METHODS A systematic search was conducted in three databases for studies on GI bleeding patients with CKD or endstage renal disease(ESRD) with data on outcomes of mortality, transfusion requirement, rebleeding rate and length of hospitalization(LOH). Calculations were performed with Comprehensive Meta-Analysis software using the random effects model. Heterogeneity was tested by using Cochrane's Q and I2 statistics. Mean difference(MD) and OR(odds ratio) were calculated.RESULTS1063 articles(EMBASE: 589; PubM ed: 459; Cochrane: 15) were found in total. 5 retrospective articles and 1 prospective study were available for analysis. These 6 articles contained data on 406035 patients, of whom 51315 had impaired renal function. The analysis showed a higher mortality in the CKD group(OR = 1.786, 95%CI: 1.689-1.888, P < 0.001) and the ESRD group(OR = 2.530, 95%CI: 1.386-4.616, P = 0.002), and a rebleeding rate(OR = 2.510, 95%CI: 1.521-4.144, P < 0.001) in patients with impaired renal function. CKD patients required more unit red blood cell transfusion(MD = 1.863, 95%CI: 0.812-2.915, P < 0.001) and spent more time in hospital(MD = 13.245, 95%CI: 6.886-19.623, P < 0.001) than the controls.CONCLUSION ESRD increases mortality, need for transfusion, rebleeding rate and LOH among GI bleeding patients. Prospective patient registries and observational clinical trials are crucially needed. | Roland Hágendorn Nelli Farkas Aron Vincze Zoltán Gyongyi Dezso Csupor Judit Bajor Bálint Eross Péter Csécsei Andrea Vasas Zsolt Szakács László Szapáry Péter Hegyi Alexandra Mikó | 2017 | World Journal of Gastroenterology2017，23，47： | 3 |
| 2 | Patient safety alliance to tackle hand washing world - wide显示文摘 | Nellie B | 2005 | The Lancet2005，366，： | 1 |
| 3 | P16 expression in re- lation to human papillomavirus in liquid-based cervical smears显示文摘 | BRIGITTE S CHRISTIANE S NELLY B | 2008 | Gynecologic Oncology2008，109，2： | 1 |
| 4 | The forces that shape organizational performance measurement systems:An interdisciplinary review显示文摘 | DANNIEL B WAGGONER ANDY D NELLY MIKE P KENNERLEY | 1999 | International Journal of production economics1999，，8： | 1 |
| 5 | A review of indicators of climate change for use in Ireland 显示文摘 | DON'NELLY A JONES M B SWEENEY J | 2004 | International Journal of Biometeorology2004，49，1： | 1 |
| 6 | Interior structure of Neptune:Comparison with Uranus显示文摘 | HUBBARD W B NELLIS W J MITCHELL A C | 1991 | Science1991，253，64： | 1 |
| 7 | New method for quantitative determination of uronc acid显示文摘 | Nelly B K Gustar A H | 1973 | Anal Biochem1973，，54： | 1 |
| 8 | Spontaneous raman scattering from shocked water显示文摘 | Holmes N C Nellis W J Graham W B | 1985 | Phys Rev Lett1985，55，： | 1 |
| 9 | New method for quantitative determination of uronic acids显示文摘 | Nelly B Gustau A | 1973 | Analy Biochem1973，，54： | 1 |
| 10 | Patient safety alliance to tacklehand washing world - wide显示文摘 | Nellie B | 2005 | The Lancet2005，366，： | 1 |
| 11 | Patient safety alliance to tackle hand washing world -wide显示文摘 | Nellie B | 2005 | The Lancet2005，366，： | 1 |
| 12 | Patient safety alliance to tackle hand washing world-wide显示文摘 | Nellie B | 2005 | The Lancet2005，366，： | 1 |
| 13 | Patient safety alliance to tackle hand washing world-wide显示文摘 | Nellie B | 2005 | The Lancet2005，366，： | 1 |
| 14 | 查看详情显示文摘 | Karl-Heinz O Nelly A Singh B | | 0，，6： | 1 |
| 15 | Molecular dissociation and shock - induced cooling in fluid nitrogen at high densities and temperatures显示文摘 | Radousky H B Nellis W J Ross M at al | 1986 | Physical Review Letters1986，57，： | 1 |
| 16 | Stably embedded minimal hypersurfaces 显示文摘 | NELLI B SORET M | 2007 | Math Z2007，255，49： | 1 |
| 17 | Myocardial metabolism in chronic reperfusion after nontransmural infarction in pig hearts显示文摘 | Liedtke A J Renstrom B Nellis SH | 1993 | Am J Physiol1993，265，30： | 1 |
| 18 | Isolation of 12 polymorohic microsatellite loci in the phytopathogenic fungus Alternaria brassicicola显示文摘 | Avenot H D Anita B S Nelly I V | 2005 | Molecular Ecoloy Notes2005，5，4： | 1 |
| 19 | Nationwide study of the prevalence,characteristics,and molecular epidemiology of extended-spectrum-β-lactamase-producing enterobacteriaceae in france显示文摘 | Muriel G Jean-Winoc D Nelly B | 2008 | Antimicrob Agents Chemother2008，52，2： | 1 |
| 20 | Patient safety alliance to tackle hand washing world wide 显示文摘 | Nellie B | 2005 | The Lancet2005，366，： | 1 |
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