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| 1 | Leukemia:研究鉴定出与34种AML白血病亚群相关联的基因突变显示文摘针对成年急性髓细胞白血病(acute myeloid leukemia,AML)患者的一项新的大型研究将80种癌症相关基因突变与5种AML亚型相关联。这5种AML亚型可通过特异性的染色体异常加以确定。在未来,这些发现可能有助指导基因突变测试和治疗决策。 | A-K Eisfeld K Mrózek J Kohlschmidt D Nicolet S Orwick C J Walker K W Kroll J S Blachly A J Carroll J E Kolitz B L Powell E S Wang R M Stone A de la Chapelle J C Byrd C D Bloomfield | 2017 | 现代生物医学进展2017，17，15： | 7 |
| 2 | Repetitive cycles of high dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16:16)(p13:q22): results from CALGB 8461显示文摘 | Byrd JC Ruppert AS Mr 6 zek K | 2004 | J Clin Oncol2004，22，6： | 1 |
| 3 | Cytogenetics and molecular genetics of acute lymphoblastic leukemia显示文摘 | Mrózek K Harper DP Aplan PD | | 0，，05： | 1 |
| 4 | Pretreatment cytogenetic abnormalities are predictive of induction success,cumulative incidence of relapse,and overall survival in adult patients with de novo acute myeloid leukemia:Results from Cancer and Leukemia Group B(CALGB8461)显示文摘 | Byrd JC Mrózek K Dodge RK | 2002 | Blood2002，100，13： | 1 |
| 5 | Cytogenetics in acute leukemia显示文摘 | Mrózek K Heerema NA Bloomfield CD | 2004 | Blood Rev2004，18，2： | 1 |
| 6 | Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?显示文摘 | Mrózek K Marcucci G Paschka P | 2007 | Blood2007，109，2： | 1 |
| 7 | Cytogenetics in acute leukemia显示文摘 | Mrózek K Heerema NA Bloomfield CD | 2004 | Blood Rev2004，18，2： | 1 |
| 8 | Pretreatment cytogenetic abnormalities are predictive of induction SUCCESS,cumulative incidence of relapse,and overall survival in adult patients with de novo acute myeloid Ieukemia:results from Cancer and Leukemia Group B (CALGB 8461)显示文摘 | Byrd JC Mr(O)zek K Dodge RK | 2002 | Blood2002，100，13： | 1 |
| 9 | Pretreatment cytogenetic abnormalities are Predictive of induction success,cumulative incidence of relapse,and over all survival in adult patients with de novo acute myeloid leukemia :results from Cancer and Leukemia Group B (CALGB 8461)显示文摘 | Byrd JC Mr zek K Dodge RK | 2002 | Blood2002，100，： | 1 |
| 10 | Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv (16)(p13q22) or t(16;16)(p13;q22):results from CALGB 8461显示文摘 | Byrd JC Ruppert AS Mrózek K | 2004 | J Clin Oncol2004，22，6： | 1 |
| 11 | Prospective Karyotype Analysisin Adult Acute Lymphoblastic Leukemia: The Cancer and Leukemia Group B Experience显示文摘 | Wetzler M Dodge R K Mrózek K | 1999 | Blood1999，93，11： | 1 |
| 12 | Chromosome aberrations,gene mutations and expression changes,and prognosis in adult acute myeloid leukemia显示文摘 | Mrózek K Bloomfield CD | 2006 | Hematology Am Soc Hematol Educ Program2006，，： | 1 |
| 13 | Prospective karyotype analysis in adult acute lymphoblastic leukemia: the cancer and leukemia Group B experience显示文摘 | Wetzler M Dodge RK Mr zek K | 1999 | Blood1999，93，11： | 1 |
| 14 | Repetitive cycles of highdose cytarabine benefit patients with acute myeloid leukemia and inv (16) (p13q22) or t (16 ; 16) (pl 3 ; q22):results from CALGB 8461显示文摘 | Byrd JC Ruppert AS Mrózek K | 2004 | J Clin Oncol2004，22，6： | 1 |
| 15 | Diagnostic and prognostic value ofcytogenetics in acute myeloid leukemia显示文摘 | Grimwade D Mrózek K | 2011 | Hematol Oncol ClinNorth Am2011，25，6： | 1 |
| 16 | Prognostic gene mutation and distinct gene-and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8显示文摘 | Becker H Maharry K Mrózek K | 2014 | Leukemia2014，28，8： | 1 |
| 17 | Adult de novo acute myeloid leukemia with t (6;11)(q27;q23):results from Cancer and Leukemia Group B Study 8461 and review of the literature显示文摘 | Blum W Mrózek K Ruppert AS | 2004 | Cancer2004，101，： | 1 |
| 18 | Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes显示文摘 | Baldus CD Liyanarachchi S Mr zek K | 2004 | PNAS2004，101，11： | 1 |
| 19 | Molecular heterogeneity and prognostic biomarkers in adults with acute myeloid leukemia and normal cytogenetics显示文摘 | Marcucci G Mr o zek K Bloomfield CD | 2005 | Curt Opin Hematol2005，12，： | 1 |
| 20 | Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics:are we ready for a prognostically prioritized molecular classification显示文摘 | Mrózek K Marcucci G Paschka P | 2007 | Blood2007，109，2： | 1 |
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