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21篇 您的检索式:作者名="Moxham C"
    题名 作者 年代 出处 被引量
1Repetitive stimulation of phrenic nerves in myasthenia gravis显示文摘Mier A Brophy C Moxham J 1992Thorax1992,47,8:1
2Jun N-terminal kinase mediates activation of skeletal muscle glycogen synthase by insulin in vivo显示文摘Moxham C M 1996J Biol Chem1996,,30:1
3Novel benzofuran and benzothiophene biphenyls as inhibitors of protein tyrosine phosphatase 1B with antihyperglycemic properties显示文摘Malamas M S Sredy J Moxham C 2000J Med Chem2000,43,7:1
4Mo- dem phenotypic drug discovery is a viable, neoclassic pharma strategy 显示文摘LEE J A UHLIK M T MOXHAM C M 2012J Med Chem2012,55,:1
5Repetitive stimulation of phrenic nerves in myasthenia gravis显示文摘Mier A Brophy C Moxham J 1992Thorax1992,47,6:1
6Repetitive stimulation of phrenic nerves in myasthenia gravis显示文摘Mier A Brophy C Moxham J 1992Thorax1992,47,6:1
7Prerequisites for theimplemen-tation of the SMED methodology:A study in atextile processing environment显示文摘Moxham C Greatbanks R 2001Int J Qual Reliab Man2001,18,4:1
8Twitch pressures in the assessment of diaphragm weakness 显示文摘Mier A Brophy C Moxham J 1989Thorax1989,44,12:1
9Novel benzofuran and benzothiophene biphanyls as inhibitor of protein tyrosine phosphatase 1B with antihyperglycemic properties 显示文摘Malamas M S Sredy J -Moxham C 2000J Med Chem2000,43,:1
10Novel benzofuran and benzothiophene biphenyls as inhibitors of protein tryosine phosepheatase 1B with antihyperglycemic properties显示文摘Malamas M S Sredy J Moxham C 2002J Med Chem2002,43,:1
11Induction of Gia2-specific antisense RNA in vivo inhibits neonatal growth 显示文摘Moxham C M Hod Y Malbon C C 1993Science1993,260,5110:1
12睡眠呼吸暂停事件时的呼吸中枢驱动显示文摘呼吸中枢驱动在阻塞性睡眠呼吸暂停(OSA)的发生发展中起着重要作用,已由研究结果显示呼吸中枢驱动的回路增益是OSA发生的重要机制之一,准确了解睡眠呼吸事件过程中的呼吸中枢驱动对认识OSA的发生机制有重要价值。长期以来,评价OSA患者的呼吸中枢驱动的主要指标为食道压,有学者发现食道压受到气流、肺容量及腹肌活动等的影响,在评价以气流变化为特征的OSA患者的呼吸中枢驱动时有其局限性。罗远明 吴海弟 汤静 Jolley C Steier J Moxham J 钟南山 Polkey MI 2010中华结核和呼吸杂志2010,33,9:1
13Assessment of diaphragm weakness显示文摘 Brophy C Moxham J 1988Am Rev Respir Dis1988,137,:1
14Ensulia action impaired by deficiency of the G-protein subunit Gia2显示文摘Moxham C M Malbon C C 1996Nature1996,379,6548:1
15Influence of lung volume and rib cage configuration on transdiaphragmatic pres- sure during phrenic nerve stimulation in man显示文摘MIER A BROPHY C MOXHAM J 1990Respir Physiol1990,80,:1
16effectiveness and cost - ef-fectiveness of a new out - patient Breathlessness Support Service : studyprotocol of a phase III fast - track randomised controlled trial显示文摘Bausewein C Jolley C Moxham JD 2012BMC Pulm Med2012,12,1:1
17Short term effect of oxygen on renal haemodynamics in patients with hypoxae- mic chronic obstructive airways disease 显示文摘S V Baudouin J Bott A Ward C Deane J Moxham 1992Thorax1992,47,:1
18Hormone therapy for preventing cardiovascular disease in post-menopausal women显示文摘Main C Knight B Moxham T 2013Cochrane Database Syst Rev2013,4,:1
19Clinical utilities and end-user experience of pharmacogenomics:39 mo of clinical implementation experience in an Australian hospital setting显示文摘BACKGROUND Pharmacogenomics(PG)testing is under-utilised in Australia.Our research provides Australia-specific data on the perspectives of patients who have had PG testing and those of the clinicians involved in their care,with the aim to inform wider adoption of PG into routine clinical practice.AIM To investigate the frequency of actionable drug gene interactions and assess the perceived utility of PG among patients and clinicians.METHODS We conducted a retrospective audit of PG undertaken by 100 patients at an Australian public hospital genetics service from 2018 to 2021.Via electronic surveys we compared and contrasted the experience,understanding and usage of results between these patients and their clinicians.RESULTS Of 100 patients who had PG,84% were taking prescription medications,of which 67% were taking medications with actionable drug-gene interactions.Twenty-five out of 81 invited patients and 17 out of 89 invited clinicians completed the surveys.Sixty-eight percent of patients understood their PG results and 48% had medications changed following testing.Paired patient-clinician surveys showed patient-perceived utility and experience was positive,contrasting their clinicians’hesitancy on PG adoption who identified insufficient education/training,lack of clinical support,test turnaround time and cost as barriers to adoption.CONCLUSION Our dichotomous findings between the perspectives of our patient and clinician cohorts suggest the uptake of PG is likely to be driven by patients and clinicians need to be prepared to provide information and guidance to their patients.Rosalind Moxham Andrew Tjokrowidjaja Sophie Devery Renee Smyth Alison McLean Darren M Roberts Kathy H C Wu 2023World Journal of Medical Genetics2023,11,4:0
20用膈肌肌电和食管压鉴别阻塞性与中枢性睡眠呼吸暂停显示文摘睡眠呼吸暂停可分为巾枢性(CSA)和阻塞性睡眠呼吸暂停(OSA)。由于CSA与OSA的发病机制及治疗方法不同,准确区别二者在临床和科研上都十分重要。鉴别CSA与OSA的经典方法是依靠睡眠多导图特别是气流和胸腹带信号。肖气流停止时,如果胸腹带信号无波动,则这一事件定义为CSA;相反如果气流信号停止时,胸腹带信号波动依然存在,则将事件定义为OSA。罗远明 汤静 Jolley C Steier J 钟南山 Moxham J Polkey MI 2010中华结核和呼吸杂志2010,33,11:0
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