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836篇 您的检索式:作者名="Moran D"
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1Combination of corticosteroids and 5-aminosalicylates or corticosteroids alone for patients with moderate-severe active ulcerative colitis:A global survey of physicians'practice显示文摘AIM To examine treatment decisions of gastroenterologists regarding the choice of prescribing 5-aminosalycilates(5ASA) with corticosteroids(CS) versus corticosteroids alone for patients with active ulcerative colitis(UC). METHODS A cross-sectional questionnaire exploring physicians' attitude toward 5ASA + CS combination therapy vs CS alone was developed and validated. The questionnaire was distributed to gastroenterology experts in twelve countries in five continents. Respondents' agreement with stated treatment choices were assessed by standardized Likert scale. Background professional characteristics of respondents were analyzed for correlation with responses. RESULTS Six hundred and sixty-four questionnaires were distributed and 349 received(52.6% response rate). Of 340 eligible respondents, 221(65%) would continue 5ASA in a patient hospitalized for intravenous CS treatment due to a moderate-severe UC flare, while 108(32%) would stop the 5ASA(P < 0.001), and 11(3%) are undecided. Similarly, 62% would continue 5ASA in an out-patient starting oral CS. However, only 140/340(41%) would proactively start 5ASA in a hospitalized patient not receiving 5ASA before admission. Most(94%) physicians consider the safety profile of 5ASA as very good. Only 52% consider them inexpensive, 35% perceive them to be expensive and 12% are undecided. On multi-variable analysis, less years of practice and perception of a plausible additive mechanistic effect of 5ASA + CS were positively associated with the decision to continue 5ASA with CS. CONCLUSION Despite the absence of data supporting its benefit, most gastroenterologists endorse combination of 5ASA + CS for patients with active moderate-to-severe UC. Randomized controlled trials are needed to assess if 5ASA confer any benefit for these patients.Shomron Ben-Horin Jane M Andrews Konstantinos H Katsanos Florian Rieder Flavio Steinwurz Konstantinos Karmiris Jae Hee Cheon Gordon William Moran Monica Cesarini Christian D Stone Doron Schwartz Marijana Protic Xavier Roblin Giulia Roda Min-Hu Chen Ofir Har-Noy Charles N Bernstein 2017World Journal of Gastroenterology2017,23,16:3
2The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery显示文摘K. S?ndenaa P. Quirke W. Hohenberger K. Sugihara H. Kobayashi H. Kessler G. Brown V. Tudyka A. D’Hoore R. H. Kennedy N. P. West S. H. Kim R. Heald K. E. Storli A. Nesbakken B. Moran 2014International Journal of Colorectal Disease2014,,4:3
3Premature failure of externally plated reinforced concrete beams 显示文摘Oehlers D J Moran J P 1990Journal of Structural Engineering1990,116,4:2
4Pathophysiology of protracted acute renal failure in man显示文摘MORAN S M MYERS B D 1985J Clin Invest1985,76,4:1
5The Open Agent Architecture: A Framework for building Distributed Software Systems显示文摘Martin D Cheyer A Moran D 1999Applied Artificial Intelligence1999,13,2:1
6Gastrointestinal stromal tumors with prominent myxoid matrix显示文摘Suster S Sorace D Moran CA 1995Am J Surg Pathol1995,19,1:1
7Novel stapling techniques to facilitate low anterior resection for rectal cancer显示文摘Moran BJ Docherty A Finnis D 1994Br J Surg1994,81,:1
8Integrins as therapeutic tar gets:lessons and opportunities显示文摘Cox D Brennan M Moran N 2010Nat Rev Drug Discov2010,9,10:1
9The concentration of deep sea gas hydrates from downhole electrical resistivity logs and laboratory data显示文摘 Yuan T Moran K 1999Earth and P lanetary Science Letters1999,172,:1
10Acoustic array trackingperformance under moderately complex environmental conditions显示文摘Moran M L Greenfield R J Wilson D K 2007Applied Acoustics2007,68,10:1
11A physiological strain index to evaluate heat stress显示文摘Moran D S Shitzer A Pandolf K B 1998Am J Physiol1998,275,44:1
12A Simple Control Scheme for Hybrid Active Power Filter显示文摘Rivas D Moran L Dixon J 2002IEE Proc on Gener Transm and Distrib2002,2002,:1
13Evaluating the cost-effectiveness of globalbiochar mitigation potential显示文摘Pratt K Moran D 2010Biomass and Bioenergy2010,34,8:1
14Relative efficiency of two warming devices during laparoscopic cholecystectomy 显示文摘Kadam VR Moyes D Moran JL 2009Anaesth Intensive Care2009,37,:1
15Polyvinyl alcohol particles sizeand suspension characteristerics显示文摘 Moran C J Cross D T 1995Am J Neuroradiol1995,16,6:1
16A simple signal processing architecture for instantaneous radar polarimetry 显示文摘Howard S D Calderbank A R Moran W 2007IEEE Transactions on Information Theory2007,53,4:1
17An environment stress index (ESI) as a substitute for the wet bulb globe temperature (WBGT)显示文摘MORAN D S PANDOLF K B SHAPIRO Y 2001Journal of Thermal Biology2001,,26:1
18Assessment of adrenal reserve in pregnancy: defining the normal response to the adrenocorticotropin stimulation test 显示文摘Suri D Moran J Hibbard JU 2006J Clin Endoerinol Metab2006,91,10:1
19Future cardiovascular dis- ease in China: Markov model and risk factor scenario pro- jections from the coronary heart disease policy model-China 显示文摘Moran A Gu D Zhao D 2010Circulation2010,3,3:1
20Future cardiovascular disease in China: markov model and risk factor scenario projections from the coronary heart disease policy model-china 显示文摘Moran A Gu D Zhao D 2010Circulation- Cardiovascular Quality and Outcomes2010,3,3:1
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