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4篇 您的检索式:作者名="Mohan R Dasu"
    题名 作者 年代 出处 被引量
1Toll-like receptor expression and signaling in human diabetic wounds显示文摘AIM: To examine the contribution of toll-like receptors(TLRs) expression and activation to the prolonged inflammation often seen in human diabetic wounds.METHODS: Debridement wound tissue was collected from diabetic patients with informed consent. Total RNA and protein were isolated and subjected to real-time polymerase chain reaction and Western blot analyses. RESULTS: TLR1, 2, 4, and 6 mRNA expressions were increased significantly in wounds of diabetic patients compared with non-diabetic wounds(P < 0.05). MyD88 protein expression was significantly increased in diabetic wounds compared to non-diabetic wounds. Interleukin-1beta, tumor necrosis factor-alpha concentration nuclear factor-kappa B activation, and thiobarbituric acid reactive substances were increased in diabetic wounds compared to non-diabetic wounds(P < 0.01). CONCLUSION: Collectively, our novel findings show that increased TLR expression, signaling, and activation may contribute to the hyper inflammation in the human diabetic wounds.Mohan R Dasu Sandra J Martin 2014World Journal of Diabetes2014,5,2:2
2Gene expression profiles and protein balance in skeletal muscle of burned children after β -adrenergic blockade显示文摘David N H Mohan R K Dasu R 2003Am J Physiol Endocrinol Metab2003,285,:1
3IGF - Ⅰ gene transfer effects on inflammatory elements present after thermal trauma 显示文摘Mohan R K Dasu David N Herndon Olivera Nesic 2003Am J physiol Regul Integr Comp Physiol2003,12,:1
4Increased Toll-Like Receptor (TLR) Activation and TLR Ligands in Recently Diagnosed Type 2 Diabetic Subjects显示文摘Dasu Mohan R Devaraj Sridevi Park Samuel Jialal Ishwarlal 2010Diabetes Care2010,,4:1
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