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您的检索式：作者名="Mo Chaoran"
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| 1 | The mechanism study of glycosides of cistanches improv ing cognitive performance dysfunction in senescence accelerated mouse prone 8 by AMPK/mTOR signaling pathway显示文摘To investigate the mechanism of glycosides of cistanches improving cognitive performance dysfunction in SAMP8 mice by AMPK/mTOR signaling pathway.Male 7-month-old SAMP8 mice were randomly divided into 5 groups:model group,GCs group,GCs+3-MA group,GCs+compound C group,Vehicle group.Morris water maze was used to detect the ability of learning and memory.Western blot was used to detect the protein expression of SYN,PSD-95,BDNF,LC3,AMPK and m-TOR.The escape latency of GCs group,GCs+3-MA group and GCs+compound C group were significantly shortened(P<0.05).Compared with GCs group,the escape latency and percent of time spent in the target quadrant of GCs+compound C group were significantly increased(P<0.05). | Liu Xinlang Zhou Lili Sun Yihong Mo Chaoran Jia Jianxin Yang Zhanjun | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 2 | The neuroprotective efets of total flavones of Dracoce phalum moldavica L.on Parkinson's disease model in mouse显示文摘It was found that the extract of total flavones from Dracoce phalum moldavica L.(TFD)could exert neuroprotective effect on moase Parkinson's disease(PD)model,but the underlying mechanisms remained unclear.The aim of this study was to detect the mechanisms of TFD neuroprotective effect on PD mice.The PD model was established by injection with MPTP to mice.Using behavioral experiment and ELISA test as well as immunohistochemistry and Western blot analysis,the following parameters were examined:①the falling latency and climbing time,②the content of serum MDA as well as activities of SOD and GSH-Px,③the count of dopaminergic neurons with expression of TH in the substantia nigra of model mice,and④the expression levels of TH,caspase-3,Bcl-2 and Bax in the midbrain tissue. | Zhou Lili Mo Chaoran Liu Xinlang Sun yihong Jia Jianxin Yang Zhanjun | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 3 | The mechanism study of glycosides of cistanches improving cognitive performance dysfunction in senescence accelerated mouse prone 8 by AMPK/mTOR signaling pathway显示文摘To investigate the mechanism of glycosides of cistanches improving cognitive performance dysfunction,male 7-month-old SAMP8 mice were randomly divided into 5 groups:model group,GCs group,GCs+3-MA group,GCs+Compound C group,vehicle group.Morris water maze was used to detect the ability of learning and memory. | Liu Xinlang Zhou Lili Sun Yihong Mo Chaoran Jia Jianxin Yang Zhanjun | 2021 | 解剖学杂志2021，44，S01： | 0 |
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