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| 1 | Nestin expression in the retina of rats with inherited retinal degeneration显示文摘 | Fatemeh Valamanesh Julie Monnin Nadège Morand-Villeneuve Germaine Michel Murhaf Zaher Sofiane Miloudi Deborah Chemouni Jean-Claude Jeanny Claudine Versaux-Botteri | 2013 | Experimental Eye Research2013，，： | 1 |
| 2 | Isolation and characterization of four antibacteriaJ peptides from bovine hemoglobin显示文摘 | Ve'ronique Dubois-DelvaJ Khalil Miloudi Rachid Daoud Franc?ois Krier Mostafa Kouach Gilbort Briand Didier Guillochon | 2006 | peptides2006，27，20： | 1 |
| 3 | Microstructural evolution of the CHOOZ A PWR surveillance program material: small angel neutron scattering and tomographic atom probe studies 显示文摘 | PAREIGE P AUGER P MILOUDI S | 1997 | Phys1997，222，： | 1 |
| 4 | Improved direct torque control of permanent magnet synchro- nous electrical vehicle motor with proportional-integral resistance estimator 显示文摘 | HARTANI K MILOUD Y MILOUDI A | 2010 | Journal of Electrical Engineering & Technology2010，5，3： | 1 |
| 5 | A New Control Strategy of Direct Torque Fuzzy Control of a PWM Inverter Fed Induction Motor Drive显示文摘 | MILOUDI A ALRADADI E A DRAOU A | 2006 | IEEE ISIE2006，，912： | 1 |
| 6 | Genetic variation of the durum wheat landrace Haurani from different agro-ecological regions显示文摘 | Mario A. Pagnotta Alfredo Impiglia Oronzo A. Tanzarella Miloudi M. Nachit Enrico Porceddu | 2003 | Genetic Resources and Crop Evolution2003，，8： | 1 |
| 7 | Application of fuzzy logic for a ripple reduction strategy in DTC scheme of a PWM inverter fed induction motor drives显示文摘 | Aimer A F Bendiabdellah A Miloudi A | 2009 | Journal of electrical systems2009，，1： | 1 |
| 8 | Isolation and characterization of four antibacterial peptides from bovine hemoglobin显示文摘 | Naima Nedjar-Arroume Véronique Dubois-Delval Khalil Miloudi Rachid Daoud Fran?ois Krier Mostafa Kouach Gilbert Briand Didier Guillochon | 2006 | Peptides2006，，9： | 1 |
| 9 | Systemic inflammation perturbs developmental retinal magic genesis and neuroretinal function 显示文摘 | Tremblay S Miloudi K Chaychi S Favret S Binet F Polosa A | 2013 | Invest Ophtholmol Vis Sci2013，54，13： | 1 |
| 10 | Isolation and characterization of four antibacterial peptides from bovine hemoglobin显示文摘 | Nedjar-Arroume N Dubois-Delval V Miloudi K | 2006 | Peptides2006，27，9： | 1 |
| 11 | Acute appendicitis in pregnancy: specific features of diagnosis and treatment显示文摘 | Miloudi N Brahem M Ben Abid S | 2012 | J Visc Surg2012，49，4： | 1 |
| 12 | Isolation and characterization of four antibacterial peptides from bovine hemoglobin显示文摘 | Nedjar-Arroume N Dubois-Delval V Miloudi K | 2006 | Peptides2006，27，9： | 1 |
| 13 | Duodenal duplication treated surgically显示文摘 | Miloudi N Mzoughi Z Ben Abid S | 2012 | Tunis Med2012，90，11： | 1 |
| 14 | Iso- lation and characterization of four antibacterial peptides from bovine hemoglobin 显示文摘 | Nedjar-Arroume N Dubois-Delval V Miloudi K | 2006 | Peptides2006，27，9： | 1 |
| 15 | Bo- vine hemoglobin: An attractive source of antibacterial pep- tides 显示文摘 | Nedjar-Arroume N Dubois-Delval V Miloudi K | 2008 | Peptides2008，29，6： | 1 |
| 16 | Acute appendicitis in preg-nancy : specific features of diagnosis and treatment 显示文摘 | Miloudi N Brahem M Ben Abid S | 2012 | J Visc Surg2012，49，4： | 1 |
| 17 | Isolation and characterization of four antibacterial peptides from bovine hemoglobin 显示文摘 | NEDJAR-ARROUME N DUBOIS-DELVAL V MILOUDI K | 2006 | Peptides2006，27，9： | 1 |
| 18 | Sudden onset of paraplegia caused by hemorrhagic spinal epidural angiolipoma. A case report显示文摘 | Ali Akhaddar Abderrahmane Albouzidi Brahim Elmostarchid Miloudi Gazzaz Mohamed Boucetta | 2008 | European Spine Journal2008，，2： | 1 |
| 19 | The mode of administration of total parenteral nutrition and nature of lipid content influence the generation of peroxides and aldehydes显示文摘 | Khalil Miloudi Blandine Comte Thérèse Rouleau Alain Montoudis Emile Levy Jean-Claude Lavoie | 2012 | Clinical Nutrition2012，，4： | 1 |
| 20 | AB018.Ocular hypertension promotes early mitochondrial fragmentation in retinal endothelial cells in a mouse model of glaucoma显示文摘Background:Retinal endothelial cells are very active and contribute to the integrity of the neurovascular unit.Vascular dysfunction has been proposed to contribute to the pathogenesis of glaucoma.Here,we evaluated the hypothesis that ocular hypertension triggers mitochondrial alterations in endothelial cells impairing the integrity of the blood retinal barrier(BRB).Methods:Ocular hypertension was induced by injection of magnetic microbeads into the anterior chamber of EndoMito-EGFP mice,a strain expressing green fluorescent protein selectively in the mitochondria of endothelial cells.Capillary density,mitochondrial volume,and the number of mitochondrial components were quantified in 3D-reconstructed images from whole-mounted retinas using Imaris software.Dynamin-related protein(DRP-1),mitofusin-2(MFN-2)and optic atrophy-1(OPA-1)expression were assessed by western blot analysis of enriched endothelial cells.Mitochondrial structure was evaluated by transmission electron microscopy(TEM)and oxygen consumption rate was monitored by Seahorse analysis.The integrity of the BRB was evaluated by quantifying Evans blue leakage.Results:Our data demonstrate that two and three weeks after ocular hypertension induction,the total mitochondria volume in endothelial cells decreased from 0.140±0.002µm3 from non-injured retinas to 0.108±0.005 and 0.093±0.007µm3,respectively in glaucomatous eyes(mean±S.E.M,ANOVA,P<0.001;N=6/group).Frequency distribution showed a substantial increase of smaller mitochondria complexes(<0.5µm3)in endothelial cells from glaucomatous retinas.Significant upregulation of DRP-1 was found in vessels isolated from glaucomatous retinas compared to the intact retinas,while MFN-2 and OPA-1 expression was not affected.Structural alteration in endothelial cell mitochondria was confirmed by TEM,which were accompanied by a 1.93-fold reduction in the oxygen consumption rate as well as 2.6-fold increase in vasculature leakage in glaucomatous retinas(n=3-6/group).In addition,this model did not trigger changes in the density of the vascular network,suggesting that mitochondrial fragmentation was not due to endothelial cell loss.Conclusions:This study shows that ocular hypertension leads to early alterations in the dynamic of endothelial cell mitochondria,contributing to vascular dysfunction in glaucoma. | Jorge L.Cueva Vargas Yoko Ito Khalil Miloudi Ariel M.Wilson Christine Vande Velde Przemyslaw Sapieha Adriana Di Polo | 2018 | Annals of Eye Science2018，，1： | 0 |
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