4篇
您的检索式：作者名="Miho Shimada"
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| 1 | Evidence for association between vitamin D receptor BsmI polymorphism and type 1 diabetes in Japanese显示文摘 | Akira Shimada Yasuhiko Kanazawa Yoshiko Motohashi Satoru Yamada Taro Maruyama Hiroshi Ikegami Takuya Awata Eiji Kawasaki Tetsuro Kobayashi Koji Nakanishi Yumiko Kawabata Susumu Kurihara Miho Uga Shoichiro Tanaka | 2007 | Journal of Autoimmunity2007，，4： | 1 |
| 2 | SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53显示文摘 | Zhanyun Tang Wei-Yi Chen Miho Shimada Uyen T.T. Nguyen Jaehoon Kim Xiao-Jian Sun Toru Sengoku Robert K. McGinty Joseph P. Fernandez Tom W. Muir Robert G. Roeder | 2013 | Cell2013，，2： | 1 |
| 3 | Leukocytes are the major target of hepatitis C virus infection: Possible mechanism of multiorgan involvement including the heart显示文摘 | Akira Matsumori Miho Shimada Tsutomu Obata | 2010 | CVD Prevention and Control2010，，2： | 1 |
| 4 | Two target gene activation pathways for orphan ERR nuclear receptors显示文摘Estrogen-related receptors(ERRα/β/γ)are orphan nuclear receptors that function in energy-demanding physiological processes,as well as in development and stem cell maintenance,but mechanisms underlying target gene activation by ERRs are largely unknown.Here,reconstituted biochemical assays that manifest ERR-dependent transcription have revealed two complementary mechanisms.On DNA templates,ERRs activate transcription with just the normal complement of general initiation factors through an interaction of the ERR DNA-binding domain with the p52 subunit of initiation factor TFIIH.On chromatin templates,activation by ERRs is dependent on AF2 domain interactions with the cell-specific coactivator PGC-1α,which in turn recruits the ubiquitous p300 and MED1/Mediator coactivators.This role of PGC-1αmay also be fulfilled by other AF2-interacting coactivators like NCOA3,which is shown to recruit Mediator selectively to ERRβand ERRγ.Importantly,combined genetic and RNA-seq analyses establish that both the TFIIH and the AF2 interaction-dependent pathways are essential for ERRβ/γ-selective gene expression and pluripotency maintenance in embryonic stem cells in which NCOA3 is a critical coactivator. | Tomoyoshi Nakadai Miho Shimada Keiichi Ito Murat Alper Cevher Chi-Shuen Chu Kohei Kumegawa Reo Maruyama Sohail Malik Robert G Roeder | 2023 | Cell Research2023，33，2： | 0 |
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