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| 1 | Development of the Documentation and Appraisal Review Tool for systematic reviews显示文摘AIM:To develop a tool to more explicitly assess and document the quality of systematic reviews.METHODS:We developed the Documentation and Appraisal Review Tool(DART)using epidemiologic principles of study design and the following resources:the modified Overview Quality Assessment Questionnaire(modified OQAQ),Assessment of Multiple Systematic Reviews(AMSTAR),the Cochrane Handbook,and the standards promoted by the Agency for Healthcare Research and Quality,and the Institutes of Medicine(IOM).We designed the DART tool to include the following:more detail to provide guidance and improve standardization of use,an approach to assess quality of systematic reviews addressing a variety of research designs,and additional space for recording notes to facilitate recall.DART underwent multiple rounds of testing with methodologists of varying levels of training and experience.Based on the results of six phases of pilot testing,we revised DART to improve performance,clarity and consistency.Pilot testing also included comparisons between DART,and the two most commonly used tools to evaluate the quality of systematic reviews,the modified OQAQ and AMSTAR.RESULTS:Compared to AMSTAR and modified OQAQ,DART includes two unique questions and several questions covered by modified OQAQ or AMSTAR but not both.Modified OQAQ and DART had the highest reporting consistency.Four AMSTAR questions were unclear and elicited inconsistent responses.Identifying reviewer rationale was most difficult using the modified OQAQ tool,and easiest using DART.DART allowsfor documentation of reviewer rationale,facilitating reconciliation between reviewers and documentation for future updates.DART also provides a comprehensive,systematic approach for reviewers with limited experience with systematic review methodology,to critically analyze systematic reviews.In addition,DART is the only one of the three tools to explicitly include quality review for biases specific to observational studies.This is now more widely recognized as important for assessing risk in order to generate recommendations that balance benefit to harm.The tool also includes the assessment of standards recommended by the March 2011 IOM Standards for Systematic Review.CONCLUSION:This comprehensive tool improves upon existing tools for assessing the quality of systematic reviews and guides reviewers through critically analyzing a systematic review. | Rebecca L Diekemper Belinda K Ireland Liana R Merz | 2015 | World Journal of Meta-Analysis2015，3，3： | 5 |
| 2 | Thin-film media: Current and future technology显示文摘 | Johnson K E Mate C M Merz J A | 1996 | IBM J Res Develop1996，40，： | 1 |
| 3 | Protecting subjects' interests in genetics research 显示文摘 | Merz J F Magnus D Cho M K Caplan A L | 2002 | Am J Hum Genet2002，70，4： | 1 |
| 4 | Resolving post- glacial phylogeography using high-throughput sequencing 显示文摘 | Emerson K J Merz C R Catchen J M | 2010 | Proc Natl Acad Sci USA2010，107，16： | 1 |
| 5 | A robust methodologyto study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladdercancer显示文摘 | Hanke M Hoefig K Merz H | 2010 | Urol Oncol2010，28，6： | 1 |
| 6 | Novel indirubin derivatives,promising anti-tumor agents inhibiting cyclin-dependent kinases显示文摘 | Merz K H Schwahn S Hippe F et a1 | 2004 | International Journal of Clinical Pharmacology and Therapeutics2004，42，11： | 1 |
| 7 | Synthesis and SAR of C12 C13-oxazoline derivatives of epothilone A 显示文摘 | Pfeiffer B Hanenstein K Merz P | 2009 | Bioorg Med Chem Lett2009，19，14： | 1 |
| 8 | Microvascular coronary dysfunc- tion in women-pathophysiology, diagnosis, and management显示文摘 | Kothawade K Bairey Merz CN | 2011 | Curt Probl Cardiol2011，36，8： | 1 |
| 9 | Force field design for metalloproteins显示文摘 | HooPs S C ANDERSON K W MERZ K M J | 1991 | J Am Chem Soc1991，113，22： | 1 |
| 10 | 显示文摘 | MERZ K M KOLLMAN P A | 1989 | J Am Chem Soc1989，111，： | 1 |
| 11 | Evaluating the Oversight of Scientific Misconduct 显示文摘 | REDMAN B K MERZ J F | 2005 | Accountability in Research: Policies and Quality Assurance2005，12，3： | 1 |
| 12 | Five-year follow-up study of hyperechogenicity of the substantia nigra in Parkinson’s disease显示文摘 | Berg D Merz B Rerners K | 2005 | Mov Disord2005，20，： | 1 |
| 13 | CREB in adult neurogenesis-master andpartner in the development of adult-born neurons显示文摘 | Merz K Herold S Lie DC | 2011 | Eur J Neu-rosci2011，33，： | 1 |
| 14 | Conformational preferences for hydroxyl groups in substituted tetrahydropyrans 显示文摘 | Zheng Y J Grand L Merz K M | 1992 | Journal of Computer Chemistry1992，13，： | 1 |
| 15 | A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA- 182 are related to urinary bladder cancer显示文摘 | Hanke M Hoefig K Merz H | 2010 | Urol Oncol2010，28，6： | 1 |
| 16 | A robust methodology to study u- rine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer 显示文摘 | Hanke M Hoefig K Merz H | 2010 | gml Oncol2010，28，6： | 1 |
| 17 | Resolving postglacial phylogeography using high-throughput sequencing显示文摘 | EMERSON K J MERZ C R CATCHEN J M | 2010 | Proceedings of the National Academy of Sciences2010，107，16： | 1 |
| 18 | A robust methodology to study urine microRNA as tumor marker: rnicroRNA-126 and microliNA-182 are related to urinary bladder caneer显示文摘 | Hanke M Hoefig K Merz H | 2010 | Urol Oncol2010，28，6： | 1 |
| 19 | Determination of the alkylpyrazine composition of coffee using stable isotope dilution-gas chromatography-mass spectrometry(SIDA-GC-MS)显示文摘 | Pickard S Becker I Merz K H | 2013 | Journal of Agricultural and Food Chemistry2013，61，26： | 1 |
| 20 | A robust methodology to study urine microRNA as tumor marker: microRNA- 126 and microRNA- 182 are related to urinary bladder cancer显示文摘 | Hanke M Hoefig K Merz H | 2010 | Urol Oncol2010，28，： | 1 |
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