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| 1 | Is the pancreas affected in patients with septic shock?——a prospective study显示文摘BACKGROUND:Hyperamylasemia can be observed anecdotally during the course of severe sepsis or septic shock.This study aimed to investigate the possibility of pancreatic involvement in patients with septic shock using serum pancreatic enzyme determinations and imaging techniques in 21 consecutive patients with septic shock and 21 healthy subjects as controls. METHODS:The serum activity of pancreatic amylase and lipase was assayed initially in all subjects and 24 and 48 hours after the initial observation in the 21 patients with septic shock All patients also underwent radiological examination to detect pancreatic abnormalities. RESULTS:The serum activity of pancreatic amylase was significantly higher in the 21 patients with septic shock than in the 21 control subjects during the study period while the serum activity of lipase was similar to that of the control subjects.Amylase and lipase serum activity did not significantly changed throughout the study period in the 21 patients with septic shock.None of the patients with pancreatic hyperenzymemia had clinical signs or morphological alterations compatible with acute pancreatitis CONCLUSION:The presence of pancreatic hyperenzymemia in septic shock patients is not a biochemical manifestation of acute pancreatic damage,and the management of these patients should be dependent on the clinical situation and not merely the biochemical results. | Raffaele Pezzilli Alessandra Barassi Andrea Imbrogno Dario Fabbri Antonina Pigna Antonio M.Morselli-Labate Roberto Corinaldesi Gianvico Melzi d'Eril | 2011 | Hepatobiliary & Pancreatic Diseases International2011,10,2: | 11 |
| 2 | Combined laparoscopic spleen-preserving distal pancreatectomy and islet autotransplantation for benign pancreatic neoplasm显示文摘AIM:To evaluate the safety and feasibility of laparoscopic spleen-preserving distal pancreatectomy(LSPDP)with autologous islet transplantation(AIT)for benign tumors of the pancreatic body-neck.METHODS:Three non-diabetic,female patients(age37,44 and 35 years,respectively)were declared candidates for surgery,between May and September 2011,because of pancreatic body/neck cystic lesions.The planned operation was an LSPDP associated with AIT from the normal pancreas distal to the neoplasm.Islets isolation was performed on the residual pancreatic parenchyma after frozen section examination of the margin.Purified autologous islets were infused into the portal vein by a percutaneous transhepatic approach the day after surgery.RESULTS:The procedure was performed successfully in all the three cases,and the spleen was preserved along with its vessels.Mean operation time was 283±52 min and average blood loss was 133±57 mL.Residual pancreas weights were 33,22 and 30 g,and105.200,40.390 and 94.790 islet equivalents were isolated,respectively.Surgical complications occurred in one patient(grade A pancreatic fistula).Postoperative stays were 6,6 and 7 d,respectively.Histopathological evaluation revealed mucinous cystic neoplasm in cases1 and 3,and serous cystic neoplasm in patient 2.No postoperative insulin administration was required.One patient developed a transient partial portal thrombosis2 mo after islet infusion.Patients are insulin independent at a mean follow up of 8±2 mo.CONCLUSION:Combination of LSPDP and AIT is feasible and could be effective to minimize the surgical impact for benign neoplasm of pancreatic body-neck. | Gianpaolo Balzano Michele Carvello Lorenzo Piemonti Rita Nano Riccardo Ariotti Alessia Mercalli Raffaella Melzi Paola Maffi Marco Braga Carlo Staudacher | 2014 | World Journal of Gastroenterology2014,20,14: | 4 |
| 3 | Fecal calprotectin and elastase 1 determinations in patients with pancreatic diseases: a possible link between pancreatic insufficiency and intestinal inflammation显示文摘 | Raffaele Pezzilli Alessandra Barassi Antonio M. Morselli-Labate Lorenzo Fantini Paola Tomassetti Davide Campana Riccardo Casadei Sergio Finazzi Gianvico Melzi d'Eril Roberto Corinaldesi | 2007 | Journal of Gastroenterology2007,,9: | 2 |
| 4 | Islet isolation for allotransplantation: variables associated with successful islet yield and graft function显示文摘 | R. Nano B. Clissi R. Melzi G. Calori P. Maffi B. Antonioli S. Marzorati L. Aldrighetti M. Freschi T. Grochowiecki C. Socci A. Secchi V. Carlo E. Bonifacio F. Bertuzzi | 2005 | Diabetologia2005,,5: | 1 |
| 5 | Serum amyloid A, procalcitonin, and C-reactive protein in early assessment of severity of acute pancreatitis显示文摘 | Pezzilli R Melzi D'eril GV Morselli-Labate AM | 2000 | Dig Dis Sci2000,45,6: | 1 |
| 6 | Procalcitonin is not a reliable marker for assessment of severity in acute panacreatitis without infenetious complications显示文摘 | Melzi D'Ederil GV Merlini G Finazzi S | | 0,,03: | 1 |
| 7 | Incidence and Predictors of Drug-Eluting Stent Thrombosis During and After Discontinuation of Thienopyridine Treatment显示文摘 | Flavio Airoldi Antonio Colombo Nuccia Morici Azeem Latib John Cosgrave Lutz Buellesfeld Erminio Bonizzoni Mauro Carlino Ulrich Gerckens Cosmo Godino Gloria Melzi Iassen Michev Matteo Montorfano Giuseppe Massimo Sangiorgi Asif Qasim Alaide Chieffo Carlo Br | 2007 | Circulation2007,,7: | 1 |
| 8 | Development of an ESP control logic based on force measurements provided by smart tires显示文摘 | Sabbioni E Cheli F Melzi S | 2013 | SAE International Journal of Passenger Cars-Mechanical Systems2013,6,1: | 1 |
| 9 | Bone marrow as analternative site for islet transplantation显示文摘 | Cantarelli E Melzi R Mercalli A | 2009 | Blood2009,114,20: | 1 |
| 10 | Islet isolation for allotransplantation:variables associated with successful islet yield and graft function 显示文摘 | Nano R Clissi B Melzi R | 2005 | Diabetologia2005,48,5: | 1 |
| 11 | Multiple target tracking and classification using the unscented probability hypothesis density filter显示文摘 | Melzi M Ouldali A Messaoudi Z | 2011 | Systems Signal Processing and their Applications2011,38,5: | 1 |
| 12 | Comparable Clinical Outcomes With Paclitaxel- and Sirolimus-Eluting Stents in Unrestricted Contemporary Practice显示文摘 | John Cosgrave Gloria Melzi Simon Corbett Giuseppe G.L. Biondi-Zoccai Pierfrancesco Agostoni Rade Babic Flavio Airoldi Alaide Chieffo Giuseppe M. Sangiorgi Matteo Montorfano Iassen Michev Mauro Carlino Antonio Colombo | 2007 | Journal of the American College of Cardiology2007,,24: | 1 |
| 13 | Drug-eluting stent restenosis:the pattern predicts the outcome 显示文摘 | Cosgrave J Melzi G Biondi-Zoccai GG | 2006 | J Am Coil C ardiol2006,47,: | 1 |
| 14 | Patterns of restenosis after drug-eluting stent implantation: Insights from a contemporary and comparative analysis of sirolimus- and paelitaxel-eluting stents 显示文摘 | Corbctt S J Cosgrave J Melzi G | 2006 | Eur Heart J2006,27,19: | 1 |
| 15 | Comparable clinical out- comes with paclitaxel - and sirolimus - eluting stents in unre- stricted contemporary practice 显示文摘 | Cosgrave J Melzi G Corbett S | 2007 | J Am Coil Cardiol2007,49,24: | 1 |
| 16 | Comparable clinical outcomes with paclitaxel-and sirolimus-eluting stents in unrestricted contemporary practice 显示文摘 | John Cosgrave Gloria Melzi Simon Corbett | 2007 | Journal of the American College of Cardiology2007,49,24: | 1 |
| 17 | Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function显示文摘 | Sordi V Melzi R Mercalli A | 2010 | Stem Cells2010,28,1: | 1 |
| 18 | Repeated drug-eluting stent implantation for drug-eluting stent restenosis:the same or a different stent显示文摘 | COSGRAVE J MELZI G CORBETT S | 2007 | Am Heart J2007,153,: | 1 |
| 19 | Lipid metabolism and ear- diovascular risk in HIV-1 infection and HAART: Present and fu- ture problems显示文摘 | Melzi S Carenzi L Cossu MV | 2010 | Cholesterol2010,2010,27: | 1 |
| 20 | Commutability of Calibration and Control Materials for Scruln Lipase显示文摘 | Cattozzo G Franzini C Melzi D | 2001 | Clinical Chemistry2001,47,: | 1 |