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| 1 | Efficacy and safety of liquid nitrogen cryotherapy for treatment of Barrett's esophagus显示文摘AIM To evaluate the efficacy and safety of liquid nitrogen cryotherapy as a primary or rescue treatment for BE,with and without dysplasia,or intramucosal adenocarcinoma (IMC).METHODS This was a retrospective,single-center study carried out in a tertiary care center including 45 patients with BE who was treatment-na?ve or who had persistent intestinal metaplasia(IM),dysplasia,or IMC despite prior therapy.Barrett's mucosa was resected via EMR when clinically appropriate,then patients underwent cryotherapy until eradication or until deemed to have failed treatment.Surveillance biopsies were taken at standard intervals.RESULTS From 2010 through 2014,33 patients were studied regarding the efficacy of cryotherapy.Overall,29 patients (88%) responded to cryotherapy,with 84% having complete regression of all dysplasia and cancer.Complete eradication of cancer and dysplasia was seen in 75% of subjects with IMC; the remaining two subjects did not respond to cryotherapy.Following cryotherapy,15 patients with high-grade dysplasia (HGD) had 30% complete regression,50% IM,and 7% low-grade dysplasia (LGD); one subject had persistent HGD.Complete eradication of dysplasia occurred in all 5 patients with LGD.In 5 patients with IM,complete regression occurred in 4,and IM persisted in one.In 136 cryotherapy sessions amongst 45 patients,adverse events included chest pain (1%),stricture (4%),and one gastrointestinal bleed in a patient on dual antiplatelet therapy who had previously undergone EMR.CONCLUSION Cryotherapy is an efficacious and safe treatment modality for Barrett's esophagus with and without dysplasia or intramucosal adenocarcinoma. | Kristen Suchniak-Mussari Charles E Dye Matthew T Moyer Abraham Mathew Thomas J McGarrity Eileen M Gagliardi Jennifer L Maranki John M Levenick | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 4 |
| 2 | Thermomechanical and morphological characteristics of cross-linked GAP and GAP-HTPB networks with different diisocyanates显示文摘 | Suresh Mathew S K Manu T L Varghese | 2008 | Propellants Explosives Pyrotechnics2008，33，2： | 1 |
| 3 | The role of peritoneal immunity and the tumour bearing state on the development of wound and peritoneal metastases after laparoscopy显示文摘 | Mathew G Watson D L Ellis T S | 1999 | Aust N Z J Surg1999，69，1： | 1 |
| 4 | Thermomechanical and morphological characteristics of cross-linked GAP and GAP - HTPB networks with different diisocyanates 显示文摘 | Mathew S Manu S K Varghese T L | 2008 | Propellants Explosives Pyrotechnics2008，33，2： | 1 |
| 5 | Allowing for nose radius effects in predicting the chip flow direction and cutting forces in bar turning 显示文摘 | YOUNG H T MATHEW P OXLEY P L B | 1987 | Journal of Mechanical Engineers Science1987，201，3： | 1 |
| 6 | Aldosterone promotes proximal tubular cell apoptosis:role of oxidative stress显示文摘 | Patni H Mathew J T Luan L | 2007 | Am J Physiol Renal Physiol2007，293，4： | 1 |
| 7 | Biotechnology in Defense 显示文摘 | Mathew T L | 2001 | Defense Science Journal2001，51，4： | 1 |
| 8 | Tribological proper- ties of the directionally oriented warp knit GFRP composites 显示文摘 | Mathew M T Padaki N V Rha L A | 2007 | Wear2007，263，7： | 1 |
| 9 | Thermome-chanical and morphological characteristics of crosslinked GAP and GAP-HTPB networks with different diisocyanates显示文摘 | Mathew S Manu S K Varghese T L | 2008 | Propellants Explosives Pyrotechnics2008，33，2： | 1 |
| 10 | Mycophenolate mofetil in renal allograft recipients: a pooled efficacy analysis of three randomized, double-blind, clinical studies in prevention of rejection显示文摘 | Halloran P Mathew T Tomlanovich S Groth C Hooftman L Barker C | 1997 | Transplantation1997，63，1： | 1 |
| 11 | An Empirical Test of the Fishbein Behavioral Intention Model显示文摘 | Wilson D T Mathews H L Harvey J W | 1975 | Journal of Consumer Research1975，，1： | 1 |
| 12 | Age- dependent moter deficit and dopaminergic dysfunction in DJ - 1 null mice 显示文摘 | Chen L Cagniard B Mathews T | 2005 | J Biol Chem2005，280，21： | 1 |
| 13 | Expansion of anti-mesothelin specific CD4+ and CDS+ T cell responses in patients with pancreatic carcinoma显示文摘 | Chen Y Ayaru L Mathew S ~t al | 2014 | PLoS One2014，9，88： | 1 |
| 14 | Some tests for variance components using generalized p-values显示文摘 | Mathew T | 1994 | Technometrics1994，36，： | 1 |
| 15 | Longitudinal trajectory of bacterial vaginosis during pregnancy显示文摘 | WATERS T P DENNEY J M MATHEW L | 2008 | Am J Obstet Gynecol2008，199，4： | 1 |
| 16 | A New RTD-FET Logic Family显示文摘 | Mathews R H Sage J P Gerhard Sollner T C L | 1999 | Proceeding of the IEEE1999，87，4： | 1 |
| 17 | Thermomechanical and morphological characteristics of crosslinked GAP and GAP-HTPB networks with different diisocyanates显示文摘 | Mathew S Manu S K Varghese T L | 2008 | Propellants Explosives Pyrotechnics2008，33，2： | 1 |
| 18 | Mycophenolate mofetil in renal allograft recipients: a pooled efficacy analysis of three randomized,double-blind, clinical studies in prevention of rejection 显示文摘 | Halloran P Mathew T Tomlanovich S Groth C Hooftman L Barker C | 1997 | Transplantion1997，63，： | 1 |
| 19 | A doubly asymptotic nonreflecting boundary for ground-shock analysis 显示文摘 | MATHEWS L C GEERS T L | 1987 | J Appl Mech ASCE1987，54，： | 1 |
| 20 | Some tests for variance components using generalized p-values显示文摘 | Zhou L Mathew T | 1994 | Technometrics1994，36，： | 1 |
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