|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Upper esophageal sphincter abnormalities are strongly predictive of treatment response in patients with achalasia显示文摘AIM: To investigate the relationship between upper esophageal sphincter abnormalities achalasia treatment METHODS: We performed a retrospective study of 41 consecutive patients referred for high resolution esophageal manometry with a final manometric diagnosis of achalasia. Patients were sub-divided by presence or absence of Upper esophageal sphincter(UES) abnormality, and clinical and manometric profiles were compared.Correlation between UES abnormality and sub-type(i.e.,hypertensive, hypotensive or impaired relaxation) and a number of variables, including qualitative treatment response, achalasia sub-type, co-morbid medical illness,psychiatric illness, surgical history, dominant presentingsymptom, treatment type, age and gender were also evaluated.RESULTS: Among all 41 patients, 24(58.54%) had a UES abnormality present. There were no significant differences between the groups in terms of age, gender or any other clinical or demographic profiles. Among those with UES abnormalities, the majority were either hypertensive(41.67%) or had impaired relaxation(37.5%) as compared to hypotensive(20.83%), although this did not reach statistical significance(P = 0.42). There was no specific association between treatment response and treatment type received; however, there was a significant association between UES abnormalities and treatment response. In patients with achalasia and concomitant UES abnormalities, 87.5% had poor treatment response, while only 12.5% had favorable response. In contrast, in patients with achalasia and no UES abnormalities, the majority(78.57%) had good treatment response, as compared to 21.43% with poor treatment response(P = 0.0001). After controlling for achalasia sub-type, those with UES abnormality had 26 times greater odds of poor treatment response than those with no UES abnormality(P = 0.009). Similarly, after controlling for treatment type, those with UES abnormality had 13.9 times greater odds of poor treatment response compared to those with no UES abnormality(P = 0.017).CONCLUSION: The presence of UES abnormalities in patients with achalasia significantly predicted poorer treatment response as compared to those with normal UES function. | Simon C Mathews Maria Ciarleglio Yamile Haito Chavez John O Clarke Ellen Stein Bani Chander Roland | 2014 | World Journal of Clinical Cases2014，2，9： | 5 |
| 2 | Establishing correlations of scalp field maps with other experimental variables using covariance analysis and resampling methods显示文摘 | Thomas Koenig Lester Melie-Garcia Maria Stein | 2008 | Clinical Neurophysiology2008，199，： | 1 |
| 3 | Apoptosis-associated antigens recognized by autoantibodies in patients with the autoimmune liver disease primary biliary cirrhosis显示文摘 | Christoph Peter Berg Gerburg Maria Stein Hildegard Keppeler Michael Gregor Sebastian Wesselborg Kirsten Lauber | 2008 | Apoptosis2008，，1： | 1 |
| 4 | From biomass to feedstock: one- step fractionation of lignocellulose components by the se- lective organic acid-catalyzed depolymerization of hemi- cellulose in a biphasic system 显示文摘 | T vom Stein P M Grande H Kayser F SibiUa W Leitner P Dor~nguez de Maria | 2011 | Green Chemistry2011，13，7： | 1 |
| 5 | Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC显示文摘 | Augusto Caraceni Geoffrey Hanks Stein Kaasa Michael I Ben- nett Cirmia Brunelli Nathan Chemy Ola Dale Franco De Conno Marie Fallon Magdi Hanna Dagny Faksvfig Haugen Gitte Juhl Samuel King PadKlepstad Eivor A Laugsand Marco Maltoni Se- bastiano Mercadante Maria Nabal Alessandra Pigni Lukas Rad- bmch Colette Reid Per Sjogren Patrick C Stone Davide Tassi- nail Giovambattista Zeppetella | 2012 | Lancet Oncol2012，13，2： | 1 |
| 6 | Tight glycemic control increases metabolic distress in traumatic brain injury: A randomized controlled within-subjects trial*显示文摘 | Paul Vespa David L. McArthur Nathan Stein Sung-Cheng Huang Weber Shao Maria Filippou Maria Etchepare Thomas Glenn David A. Hovda | 2012 | Critical Care Medicine2012，，6： | 1 |
| 7 | Metabolic syndrome and the role of dietary lifes- tyles in Alzheimer' s disease 显示文摘 | GIULIO MARIA PASINETYI JAEQUELINE A EBER- STEIN | 2008 | J Neurochem2008，106，4： | 1 |
| 8 | Isolation, Identification, Synthesis, and Field Evaluation of the Sex Pheromone of the Brazilian Population of Spodoptera frugiperda显示文摘 | Luciane G. Batista-Pereira Kathrin Stein André F. Paula Jardel A. Moreira Ivan Cruz Maria de Lourdes C. Figueiredo José Perri Arlene G. Corrêa | 2006 | Journal of Chemical Ecology2006，，5： | 1 |
| 9 | Mobilizing Crop Biodiversity显示文摘Over the past 70 years,the world has witnessed extraordinary growth in crop productivity,enabled by a suite of technological advances,including higher yielding crop varieties,improved farm management,synthetic agrochemicals,and agricultural mechanization.While this'Green Revolution'intensified crop production,and is credited with reducing famine and malnutrition,its benefits were accompanied by several undesirable collateral effects(Pingali,2012).These include a narrowing of agricultural biodiversity,stemming from increased monoculture and greater reliance on a smaller number of crops and crop varieties for the majority of our calories.This reduction in diversity has created vulnerabilities to pest and disease epidemics,climate variation,and ultimately to human health(Harlan,1972). | Susan McCouch Zahra Katy Navabi Michael Abberton Noelle L.Anglin Rosa Lia Barbieri Michael Baum Kirstin Bett Helen Booker Gerald L.Brown Glenn J.Bryan Luigi Cattivelli David Charest Kellye Eversole Marcelo Freitas Kioumars Ghamkhar Dario Grattipaglia Robert Henry Maria Cleria Valadares Inglis Tofazzal Islam Zakaria Kehel Paul J.Kersey Graham J.King Stephen Kresovich Emily Marden Sean Mayes Marie Noelle Ndjiondjiop Henry T.Nguyen Samuel Rezende Paiva Roberto Papa Peter W.B.Phillips Awais Rasheed Christopher Richards Mathieu Flouard Maria Jose Amstalden Sampaio Uwe Scholz Paul D.Shaw Brad Sherman S.Evan Staton Nils Stein Jan Svensson Mark Tester Jose Francisco Montenegro Valls Rajeev Varshney Stephen Visscher Eric von Wettberg Robbie Waugh Peter Wenzl Loren H.Rieseberg | 2020 | Molecular Plant2020，13，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员