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| 1 | Liver hemangioma and vascular liver diseases in patients with systemic lupus erythematosus显示文摘AIM:To investigate whether systemic lupus erythematosus (SLE) is associated with benign focal liver lesions and vascular liver diseases, since these have been occasionally reported in SLE patients. METHODS:Thirty-five consecutive adult patients with SLE and 35 age-and sex-matched healthy controls were evaluated. Hepatic and portal vein patency and presence of focal liver lesions were studied by colour-Doppler ultrasound, computerized tomography and magnetic resonance were used to refine the diagnosis, clinical data of SLE patients were reviewed. RESULTS:Benign hepatic lesions were common in SLE patients (54% vs 14% controls, P < 0.0001), withhemangioma being the most commonly observed lesion in the two groups. SLE was associated with the presence of single hemangioma [odds ratios (OR) 5.05; 95% confidence interval (CI) 1.91-13.38] and multiple hemangiomas (OR 4.13; 95% CI 1.03-16.55). Multiple hemangiomas were associated with a longer duration of SLE (9.9 ± 6.5 vs 5.5 ± 6.4 years; P = 0.04). Imaging prior to SLE onset was available in 9 patients with SLE and hemangioma, showing absence of lesions in 7/9. The clinical data of our patients suggest that SLE pos- sibly plays a role in the development of hemangioma. In addition, a Budd-Chiari syndrome associated with nodular regenerative hyperplasia (NRH), and a NRH associated with hepatic hemangioma were observed, both in patients hospitalized for abdominal symptoms, suggesting that vascular liver diseases should be specifically investigated in this population. CONCLUSION:SLE is associated with 5-fold increased odds of liver hemangiomas, suggesting that these might be considered among the hepatic manifestations of SLE. | Annalisa Berzigotti Marilena Frigato Elena Manfredini Lucia Pierpaoli Rita Mulè Carolina Tiani Paola Zappoli Donatella Magalotti Nazzarena Malavolta Marco Zoli | 2011 | World Journal of Gastroenterology2011，17，40： | 5 |
| 2 | Survival study of metallo- thionein-1 transgenic mice and respective controls(C57BL/6J) :in- fluence of a zinc - enriched environment 显示文摘 | Malavolta M Basso A Piaeenza F | 2012 | Rejuvenation Re- search2012，15，2： | 1 |
| 3 | Zinc metallothioneins and longevity: interrelationships with niacin and selenium 显示文摘 | MOCCHEGIANI E MALAVOLTA M MUTI E | 2008 | Curr Phannac Design2008，14，26： | 1 |
| 4 | Differences in prox- imal femur geometry distinguish vertebral from femoral neck fractures in osteoporotic women 显示文摘 | Gnudi S Malavolta N Testi D | 2004 | Br J Radiol2004，77，： | 1 |
| 5 | Contemporary use of Ni and Bi in hot-dip galvanizing 显示文摘 | FRATESI R RUFFINI N MALAVOLTA M BELLEZZE T | 2002 | Surf Coat Technol2002，1571，： | 1 |
| 6 | Zinc dyshomeostasis,ageing and neurodegeneration:implications of A2M and inflammatory gene polymorphisms显示文摘 | Mocchegiani E Malavolta M | 2007 | J Alzheimers Dis2007，12，1： | 1 |
| 7 | The +838 C/G MT2A polymorphism,metals,and the inflammatory/immune response in carotid artery stenosis in elderly people显示文摘 | Giacconi R Muti E Malavolta M | | 0，，7： | 1 |
| 8 | Contemporary use of Ni and Bi in hot-dip galvanizing显示文摘 | Fratesi R Ruffini N Malavolta M | 2002 | Surface & Coatings Technology2002，15，7： | 1 |
| 9 | In vivo effect of alpha - bisabolol, a nontoxic sesquiterpene alcohol, on the induction of spon- taneous mammary tumors in HER- 2/neu transgenic mice显示文摘 | Costarelli L Malavolta M Giacconi R | 2010 | Oncol Res2010，18，9： | 1 |
| 10 | Contemporary use of Ni and Bi in hot-dip galvanizing显示文摘 | Fratesi R Ruffini N Malavolta M | 2002 | Surface & Coatings Technology2002，157，1： | 1 |
| 11 | Quantitative ultrasound assessment of bone显示文摘 | Malavolta N Mule R Frigato M | 2004 | Aging Clin Exp Res2004，16，3： | 1 |
| 12 | Effectiveness of teriparatide treatment on back pain-related functional limitations in individuals affected by severe osteoporosis: a prospective pilot study 显示文摘 | Iolascon G Gimigliano F Malavolta N | 2012 | Clin Cases Miner Bone Metab2012，9，3： | 1 |
| 13 | Peptide dissociation in solution or bound to a polymer: comparative solvent effect显示文摘 | Luciana Malavolta Clovis R Nakaie | 2004 | Tetrahedron2004，60，42： | 1 |
| 14 | Contemporary use of Ni and Bi in hot dip galvanizing 显示文摘 | Fratesi R Ruffini N Malavolta M | 2002 | Surface and Coatings Technology2002，157，3： | 1 |
| 15 | Contemporary use of Ni and Bi in hot-dip galvanizing显示文摘 | FRATESI R RUFFINI N MALAVOLTA M BELLEZZE T | 2002 | Surface and Coatings Technology2002，157，1： | 1 |
| 16 | A case of lung myelolipomatosis in a patient with bronchial carcinoid显示文摘 | Zunarelli E Criscuolo M Malavolta L | | 0，，： | 1 |
| 17 | Zinc, metaUothioneins and longevity : interrelationships with niacin and sele- nium显示文摘 | MOCCHEGIANI E MALAVOLTA M COSTARELLI L | 2008 | Curt Pharm Design2008，14，26： | 1 |
| 18 | Contemporary Use of Ni and Bi in Hot-Dip Galvanizing 显示文摘 | Fratesi R Ruffini N Malavolta M | 2002 | Surface and Coatings Technology2002，157，1： | 1 |
| 19 | Contemporary use of Ni and Bi in hot dip galvanizing显示文摘 | FRATESI P RUFFINI N MALAVOLTA M | 2002 | Surface & Coatings Technology2002，157，3： | 1 |
| 20 | Zinc dyshomeostasis:a key modulator of neuronal injury显示文摘 | Capasso M Jeng JM Malavolta M | | 0，，02： | 1 |
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