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8篇 您的检索式:作者名="Maideen"
    题名 作者 年代 出处 被引量
1Entrepreneurship in the tourism industry: Issues in developing countries 显示文摘Jaafar M Abdul-Aziz A R Maideen S A 2011International Journal of Hospitality Management2011,30,4:1
2Entrepreneurship in the tourism industry: Issues in developing countries显示文摘Mastura Jaafar Abdul Rashid Abdul-Aziz Siti Aishah Maideen Siti Zaleha Mohd 2011International Journal of Hospitality Management2011,,4:1
3Ecotourism-related products and activities,and the economic sustainability of small and medium island chalets显示文摘JAAFAR M MAIDEEN S A 2012Tourism Management2012,33,3:1
4Ecotourism-related products and activities,and the economic sustainability of small and medium island chalets显示文摘Mastura Jaafar Siti Aishah Maideen 0,,:1
5A review of inherent beneficial effects of black seeds(Nigella sativa)in Marburg virus disease management显示文摘Background:In the management of patients with MARV infection,this review article focuses on the potential protective effects of black seeds(Nigella sativa).Methods:To find studies that evaluated various effects of black seeds(N.sativa)related to signs and symptoms of MARV infection,reference lists and databases such as Medline/Pubmed/PMC,Google Scholar,Science Direct,Ebsco,Scopus,Web of Science,and Embase were searched.Results:In numerous clinical,animal,in-vitro,in-vivo,and in-ovo studies,black seeds(N.sativa)have demonstrated potential antiviral,anti-inflammatory,antioxidant,immunomodulatory,and hepatoprotective properties that may aid in the treatment of MARV-infected patients.Conclusion:In the initial generalization phase of MARV infection,patients may use black seeds(N.sativa)as an adjunctive therapy in addition to symptomatic treatment and supportive care.Future randomized controlled clinical trials would confirm N.sativa’s efficacy and safety in MARV-infected patients.Pakkir Maideen 2023Food and Health2023,5,2:0
6Drug interactions of dipeptidyl peptidase 4 inhibitors involving CYP enzymes and P-gp efflux pump显示文摘Dipeptidyl peptidase 4(DPP4) inhibitors are oral antidiabetic drugs approved to manage type 2 diabetes mellitus. Saxagliptin is a substrate of CYP3A4/5 enzymes while other DPP4 inhibitors such as sitagliptin, linagliptin, gemigliptin and teneligliptin are weak substrates of CYP3A4. DPP4 inhibitors have also been identified as substrates of P-gp. Hence, the drugs inhibiting or inducing CYP3A4/5 enzymes and/or P-gp can alter the pharmacokinetics of DPP4 inhibitors. This review is aimed to identify the drugs interacting with DPP4 inhibitors. The plasma concentrations of saxagliptin have been reported to be increased significantly by the concomitant administration of ketoconazole or diltiazem while no significant interactions between various DPP4 inhibitors and drugs like warfarin, digoxin or cyclosporine have been identified.Naina Mohamed Pakkir Maideen 2019World Journal of Meta-Analysis2019,7,4:0
7Probable beneficial effects of black seeds (Nigella sativa) in the management of langya henipavirus infection显示文摘Background:The patients with Langya henipavirus(LayV)infection are managed mainly with symptomatic treatment and supportive care.Objective:This review article focuses on the beneficial effects of black seeds(Nigella sativa)in the management of Langya henipavirus(LayV)infection.Methods:The literature was searched in online databases,including Medline/Pubmed/PMC,Google Scholar,Science Direct,Ebsco,Scopus,Web of Science,Embase,and reference lists,to identify published studies,which established beneficial effects of black seeds(N.sativa)related to signs and symptoms of LayV infection.Results:Black seeds(N.sativa)have shown potential antiviral,bronchodilatory,antihistaminic,antitussive,hepatoprotective,renoprotective,anti-inflammatory,antioxidant,and immunomodulatory properties in various clinical,animal,in-vitro,in-vivo,and in-silico studies,which would help the patients with LayV infection.Conclusion:N.sativa would be a potential herbal candidate in the management of LayV infection along with symptomatic treatment and supportive care,to prevent further deterioration,and hospitalization.The safety and efficacy of N.sativa in patients with LayV infection would further be established by future randomized controlled clinical trials.Naina Mohamed Pakkir Maideen 2022Food and Health2022,4,4:0
8Tobacco smoking and its drug interactions with comedications involving CYP and UGT enzymes and nicotine显示文摘Tobacco smoking is a global public health threat causing several illnesses including cardiovascular disease(Myocardial infarction), cerebrovascular disease(Stroke), peripheral vascular disease(Claudication), chronic obstructive pulmonary disease, asthma, reduced female infertility, sexual dysfunction in men, different types of cancer and many other diseases. It has been estimated in 2015 that approximately 1.3 billion people smoke, around the globe. Use of medications among smokers is more common, nowadays. This review is aimed to identify the medications affected by smoking, involving Cytochrome P450(CYP)and uridine diphosphate-glucuronosyltransferases(UGTs) enzymes and Nicotine. Polycyclic aromatic hydrocarbons(PAHs) of tobacco smoke have been associated with the induction of CYP enzymes such as CYP1A1, CYP1A2 and possibly CYP2E1 and UGT enzymes. The drugs metabolized by CYP1A1,CYP1A2, CYP2E1 and UGT enzymes might be affected by tobacco smoking and the smokers taking medications metabolized by those enzymes, may need higher doses due to decreased plasma concentrations through enhanced induction by PAHs of tobacco smoke. The prescribers and the pharmacists are required to be aware of medications affected by tobacco smoking to prevent the toxicityassociated complications during smoking cessation.Naina Mohamed Pakkir Maideen 2019World Journal of Pharmacology2019,8,2:0
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