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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | The vegetation and climate change during Neocene and Early Quaternary in Jiuxi Basin, China显示文摘Sporopollen record in the Laojunmiao Section at Yumen in the Hexi Corridor foreland depression at the northern margin of the Tibetan Plateau revealed that during the period of 13.0―11.15 Ma the ecological environment of the Jiuxi Basin is characterized by steppe vegetation and a semi-moist climate. During 11.16―8.60 Ma prevailed forests of cypress and a still warmer, moister climate; steppe vegetation and dry climate began probably at about 8.6 Ma. Although aridification had been relaxed time and again during 8.40―6.93 Ma (forest-steppe, warm-semi-moist), 6.64―5.67 Ma (open-forest and steppe, warmer-semi-moist) and 5.42―4.96 Ma (steppe, semi-arid), the climate in the region became drier and drier in response to the fre- quent occurrence of aridity during 6.93―6.64 Ma (steppe, semi-arid), 5.67―5.42 Ma (de- sert-steppe, arid), 3.66―3.30 Ma (desert-steppe, arid) and 2.56―2.21 Ma (desert, arid). Perhaps the important findings of our study are the notable expansion of drought-enduring plants during 3.66―3.30 Ma and about 2.56 Ma and the replacement of vegetation by vast arid desert. | MA Yuzhen 1 , FANG Xiaomin 1,2 , LI Jijun 1 , WU Fuli 1 & ZHANG Jun 1 1. Key Laboratory of Western China’s Environmental Systems and College of Resources and Environment, Lanzhou University, Lanzhou 730000, China 2. State Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710075, China | 2005 | Science China Earth Sciences2005，48，5： | 31 |
| 3 | Asynchronous Brain-Computer Interface Shared Control of Robotic Grasping显示文摘The control of a high Degree of Freedom(DoF) robot to grasp a target in three-dimensional space using Brain-Computer Interface(BCI) remains a very difficult problem to solve. Design of synchronous BCI requires the user perform the brain activity task all the time according to the predefined paradigm; such a process is boring and fatiguing. Furthermore, the strategy of switching between robotic auto-control and BCI control is not very reliable because the accuracy of Motor Imagery(MI) pattern recognition rarely reaches 100%. In this paper, an asynchronous BCI shared control method is proposed for the high DoF robotic grasping task. The proposed method combines BCI control and automatic robotic control to simultaneously consider the robotic vision feedback and revise the unreasonable control commands. The user can easily mentally control the system and is only required to intervene and send brain commands to the automatic control system at the appropriate time according to the experience of the user. Two experiments are designed to validate our method: one aims to illustrate the accuracy of MI pattern recognition of our asynchronous BCI system; the other is the online practical experiment that controls the robot to grasp a target while avoiding an obstacle using the asynchronous BCI shared control method that can improve the safety and robustness of our system. | Wenchang Zhang Fuchun Sun Hang Wu Chuanqi Tan Yuzhen Ma | 2019 | Tsinghua Science and Technology2019，24，3： | 8 |
| 4 | Pollen record from red clay sequence in the central Loess Plateau between 8.10 and 2.60Ma显示文摘The Late Miocene and Pliocene are the key periods for understanding the origin and development of the present Asian monsoon circulations and ecologic environ-ments. Here we present a pollen record from Chaona Red Clay section located in the central Loess Plateau in attempt to establish the histories of vegetation and associated climate changes between 8.10 and 2.60 Ma. Our results show that Gramineae-dominated woodland-grasslands developed in this region with Cedrus- and Pinus-characterized montane coniferous forests distributing in higher elevations from 8.10 to 6.73 Ma, probably suggesting a semi-humid climate in a warm-temperate zone. A subsequent expansion of Ulmus- dominated deciduous forests and a synchronous increase of Gramineae-dominated grassland reflect a warmer and more humid climate between 6.73 and 5.67 Ma. The vegetation changed to an Artemisia- and Gramineae-characterized steppe in lower elevations and to a coniferous forest in higher elevations from 5.67 to 3.71 Ma, implying probably a warm and semiarid climate in lowland and hill, and a colder and moister climate in mountain. During this period, a consider-able warmer and more humid climate occurred between 4.61 and 4.07 Ma as indicated by pollen assemblages. The period between 3.71 and 2.58 Ma was characterized by the disap-pearance of Cedrus and Tsuga and also by an abrupt expan-sion of Cupressaceae, reflecting a drastic enhancement of monsoon-related climatic seasonality. | MA Yuzhen WU Fuli FANG Xiaomin LI Jijun AN Zhisheng WANG Wei | 2005 | Chinese Science Bulletin2005，50，19： | 7 |
| 5 | Nanoparticles carrying neurotrophin-3-modified Schwann cells promote repair of sciatic nerve defects显示文摘Schwann cells and neurotrophin-3 play an important role in neural regeneration,but the secretion of neurotrophin-3 from Schwann cells is limited,and exogenous neurotrophin-3 is inactived easily in vivo.In this study,we have transfected neurotrophin-3 into Schwann cells cultured in vitro using nanoparticle liposomes.Results showed that neurotrophin-3 was successfully transfected into Schwann cells,where it was expressed effectively and steadily.A composite of Schwann cells transfected with neurotrophin-3 and poly(lactic-co-glycolic acid) biodegradable conduits was transplanted into rats to repair 10-mm sciatic nerve defects.Transplantation of the composite scaffold could restore the myoelectricity and wave amplitude of the sciatic nerve by electrophysiological examination,promote nerve axonal and myelin regeneration,and delay apoptosis of spinal motor neurons.Experimental findings indicate that neurotrophin-3 transfected Schwann cells combined with bridge grafting can promote neural regeneration and functional recovery after nerve injury. | Haibin Zong Hongxing Zhao Yilei Zhao Jingling Jia Libin Yang Chao Ma Yang Zhang Yuzhen Dong | 2013 | Neural Regeneration Research2013，8，14： | 7 |
| 6 | Response to climate change of different tree species and NDVI variation since 1923 in the middle arid region of Ningxia,China显示文摘The normalized difference vegetation index(NDVI)is used extensively to describe vegetation cover and ecological environment change.The purpose of this study was to contrast the response of different tree species growing in the same habitat to climate change and retrieve past NDVI using tree-ring width data from tree cores collected from the transitional zone of Pinus tabulaeformis and Picea crassifolia in the Luoshan Mountains in the middle arid region of Ningxia.Correlation analysis indicated that radial growth of P.tabulaeformis is more sensitive to precipitation and temperature change than that of P.crassifolia.Natural factors such as water availability and heat at this elevation are more suited to the growth of P.crassifolia,and are more advantageous to its renewal and succession.P.crassifolia is probably the better of the two species for protecting the forest ecosystem and conserving water in the Luoshan desertification area.Ring width of P.crassifolia correlates significantly with average NDVI for April–May(r=0.641,p<0.01),and both of them are influenced positively by precipitation in April–May.The reconstructed NDVI for 1923–2007 shows the relatively low vegetation cover occurred in the 1920s–1930s,the1960s–1970s,and the early 21st century.The reconstructed NDVI better reflected the drought climate in the study area. | YaJun Wang RuiJie Lu YuZhen Ma HongWei Meng ShangYu Gao | 2014 | Research in Cold and Arid Regions2014，6，1： | 6 |
| 7 | Preface显示文摘信号处理的所有光的实现由于这条途径的唯一的潜力吸引了很多注意克服带宽和电子设备的速度瓶颈。许多所有光的信号处理技术,出现处理带宽直到几 THz,在大量区域被建议了并且成功地采用了例如 ultrafast 电信,光计算,微波 photonics,和 bio-photonics [17 ] 。 | Mingxin Tao Wanchun Wang Zhongping Li Yuzhen Ma Jing Li Xiaobin Li | 2014 | Chinese Science Bulletin2014，59，22： | 5 |
| 8 | Vegetation and climate changes during the last 8660 cal.a BP in central Mongolia,based on a high-resolution pollen record from Lake Ugii Nuur显示文摘Based on modern pollen studies and reliable chronology of nine AMS 14C dates, a detailed history of vegetation and climate changes during the past 8660 cal. a BP was reconstructed by a high-resolution pollen record from Ugii Nuur in central Mongolia. Poaceae-steppe dominated the study area and the climate was mild and semi-humid before 7800 cal. a BP with a noticeable cool and humid interval at 8350―8250 cal. a BP. Xerophytic plant increased and the climate became warm and dry gradually since 7800 cal. a BP. From 6860 to 3170 cal. a BP, semi-desert steppe expanded, suggesting a prolonged warm and dry climate. Between 3170 and 2340 cal. a BP, regional forest steppe expanded whereas semi-desert steppe retreated, indicating the climate became cool and wet gradually and the humidity reached the maximum at the end of this stage. From 2340 to 1600 cal. a BP, a general cool and wet climate prevailed. And the climatic instability increased after 1600 cal. a BP. Review of regional pub-lished palaeoclimatic records implies that the mid-Holocene dry climate might have prevailed in vast areas from central Mongolia to arid areas of northwest China. Pollen-based climate reconstruction for UG04 core was well correlated with the result of climate model on Central Asia by Bush. In addition, several abrupt climatic events (cool and wet) were found and some could be broadly compared with the cool events in Atlantic. | WANG Wei MA YuZhen FENG ZhaoDong MENG HongWei SANG YanLi ZHAI XinWei | 2009 | Chinese Science Bulletin2009，54，9： | 5 |
| 9 | New Approaches and Markers for Identifying Secondary Biogenic Coalbed Gas显示文摘According to the adsorption-desorption characteristics of coalbed gas and analysis of various experimental data,this paper proposes that the generation of secondary biogenic gas(SBG) and its mixing of with the residual thermogenic gas at an early stage inevitably lead to secondary changes of the thermogenic gas and various geochemical additive effects.Experimental results also show that the fractionation of the carbon isotope of methane of coal core desorption gas changes very little;the δ13C1 value of the mixed gas of biogenic and thermogenic gases is between the δ13C1 values of the two 'original' gases,and the value is determined by the carbon isotopic compositions and mixing proportions of the two 'original' methanes.Therefore this paper proposes that the study on the secondary changes of the thermogenic gas and various additive effects is a new effective way to study and identify SBG.Herein,a systematic example of research on the coalbed gas(Huainan coalbed gas) is further conducted,revealing a series of secondary changes and additive effects,the main characteristics and markers of which are:(1) the contents of CO2 and heavy-hydrocarbons decrease significantly;(2) the content of CH4 increases and the gas becomes drier;(3) the δ13C and δD values of methane decrease significantly and tend to have biogenetic characteristics;and(4) the values of δ13C2 and δ13CCO2 grow higher.These isotopic values also change with the degradation degrees by microbes and mixing proportions of the two kinds of gases in different locations.There exists a negative correlation between the δ13C1 vs δ13CCO2 values.The △δ13CC2-C1 values obviously become higher.The distributions of the △δ13CCO2-C1 values are within certain limits and show regularity.There exist a positive correlation between the N2 versus Ar contents,and a negative correlation between the N2 versus CH4 contents,indicating the down forward infiltration of the surface water containing air.These are important markers of the generation and existence of SBG. | TAO Mingxin LI Jing LI Xiaobin MA Yuzhen LI Zhongping WANG Zuodong GAO Zhongliang ZHANG Xiaojun WANG Yanlong | 2012 | Acta Geologica Sinica(English Edition)2012，86，1： | 4 |
| 10 | Vegetation and environmental changes in western Chinese Loess Plateau since 13.0 ka BP显示文摘从中国黄土高原的花粉记录表明植被变化和联系气候的详细历史在最后 13.0 ka BP 期间变化。在 12.1 ka BP,大草原或荒芜大草原的植被前,统治风景然后在通常湿的气候(12.111.0 ka BP ) 下面由一个具球果的森林被代替。植被被败坏进大草原风景并且进一步进在 11.0 和 9.8 ka BP 之间的一处荒芜大草原的风景。在凉爽、湿的气候(9.89.6 ka BP ) 的一个简短事件以后,一个相对温和、干燥的条件在早 Holocene (9.67.6 ka BP ) 期间占优势。温暖、潮湿的时期的最赞成的气候在或者在大草原之间改变的森林大草原风景和植被标记的 mid-Holocene (7.6-4.0 ka BP ) 期间发生了并且从 4.0 ~ 1.0 ka BP 荒芜大草原。 | SUN Aizhi FENG Zhaodong MA Yuzhen | 2010 | Journal of Geographical Sciences2010，20，2： | 4 |
| 11 | Reconstructing the annual precipitation variation since 1899 based on tree-ring width in the western Hedong sandy land of Ningxia显示文摘Based on the analysis of the correlation between the tree-ring width of Pinus tabulaeformis and the climate factors in the western Hedong sandy land of Ningxia, a conversion equation between the annual precipitation and the tree-ring width since 1899 was reconstructed. The results of cross verification indicated that the conversion equation is stable and the reconstructed results are reliable. The result of reconstructed annual precipitation showed the remarkable fluctuation of precipitation and dry-to-wet variation before the 1940s. The smaller fluctuation and high frequent changes of precipitation occurred during the period of 1940s-1980s and after the 1980s the change trend of the precipitation became high periodic extent and low frequent. The study found that there were some coincidences with the climate change in Changling Mountains, Helan Mountains and the east of Qilian Mountains. The relatively dry periods in the beginning of 20th century, 1920s to 1930s, the end of the 20th century and 2004 to 2006 in the western Hedong sandy land of Ningxia accelerated the desertification, while the relatively humid period during the periods of the 1910s-1920s, 1930s-1940s and 1990s is favorable to prevent and control the desertification, and to weaken the climate warming and drying. The periods of annual precipitation variation in the western Hedong sandy land of Ningxia since 1899 are approximately 2-4 years, 5-7 years and 10 years. | Wang, YaJun Gao, ShangYu Ma, YuZhen Lu, RuiJie Sang, YanLi Meng, HongWei | 2010 | Journal of Arid Land2010，2，4： | 3 |
| 12 | Comprehensive study on genetic pathways and parent materials of secondary biogenic gas in coalbeds显示文摘The types of substances in coal rock used by microbes,the specific ways in which microbes produce secondary biogenic gas(SBG)and whether substances exist in the coal seam for the formation of a large amount of SBG are important basic scientific issues.This paper conducts a systematic and comprehensive research study on the above issues using methods such as the isotopic tracing of gas,the analysis of coal organic geochemistry,and gas-producing simulation experiments of coal.Results show that the formation of SBG is by the microbial reduction of CO2and the SBG-producing coal seam undergoes microbial degradation.The thermogenic heavy gaseous hydrocarbons have also been degraded by microorganisms and possibly transformed into microbialoriginated CO2.A large amount of CO2,a relatively large amount of H2and a certain amount of heavy gaseous hydrocarbons may form in the thermal evolution of coal.These substances and the microbial-originated CO2and coal seam water can finally become parent materials of SBG.These components are rich in coal seams of medium–low thermal evolution,which should be the main coal seams for SBG formation and exploration. | Mingxin Tao Wanchun Wang Zhongping Li Yuzhen Ma Jing Li Xiaobin Li | 2014 | Chinese Science Bulletin2014，59，10： | 2 |
| 13 | Target suppression of connexin43 in ovine reimplantation embryos by RNA interference using double - stranded RNA显示文摘 | Yan Zhan Ma Yuzhen | 2010 | Asian - australasian journal of animal sciences2010，23，4： | 1 |
| 14 | Assay of fish freshness using trimethylamine vapor probe based on a sensitive membrane on piezoelectric quartz crystal显示文摘 | Zhao Changzhi Pan Yuzhen Ma Lingzhi | 2002 | Sensors and Actuators B2002，81，： | 1 |
| 15 | Assay of fish freshness using trimethylamine vapor probe based on a sensitive membrane on piezoelectric quartz crystal 显示文摘 | Zhao Changzhi Pan Yuzhen Ma Lingzhi | 2002 | Sensors and Actuators B2002，81，： | 1 |
| 16 | Extracellular-superoxide dismutase DNA methylation promotes oxidative stress in homocysteine-induced atherosclerosis显示文摘In the present study,we investigate the effect of homocysteine(Hcy)on extracellular-superoxide dismutase(ECSOD)DNA methylation in the aorta of mice,and explore the underlying mechanism in macrophages,trying to identify the key targets of Hcy-induced EC-SOD methylation changes.ApoE--mice are fed different diets for 15 weeks,EC-SODand DNAmethyltransferase1(DNMT1)expression levels aredetected byRT-PCRandwestern blot analysis.EC-SOD methylation levels are assessed by ntMS-PCR.After EC-SOD overexpression or knockdown in macrophages,following the transfection of macrophages with pEGFP-N1-DNMT1,the methylation levels of ECSOD are detected.Our data show that the concentrations of Hcy and the area of atherogenic lesions are significantly increased in ApoE--mice fed with a high-methionine diet,and have a positive correlation with the levels of superoxide anions,which indicates that Hcy-activated superoxide anions enhance the development of atherogenic lesions.EC-SOD expression is suppressed by Hcy,and the content of superoxide anion is increased when EC-SOD is silenced by RNAi in macrophages,suggesting that EC-SOD plays a major part in oxidative stress induced by Hcy.Furthermore,the promoter activity of EC-SOD is increased following transfection with the-1/-110o fragment,and EC-SOD methylation level is significantly suppressed by Hcy,and more significantly decreased upon DNMT1 overexpression.In conclusion,Hcy may alter the DNA methylation status and DNMT1 acts as the essential enzyme in the methyl transfer process to disturb the status of EC-SOD DNA methylation,leading to decreased expression of Ec-sODandincreasedoxidativestressandatherosclerosis. | Shengchao Ma Guanjun Lu Qing Zhang Ning Ding Yuzhen Jie Hui Zhang Lingbo Xu Lin Xie Xiaoling Yang Huiping Zhang Yideng Jiang | 2022 | Acta Biochimica et Biophysica Sinica2022，54，9： | 1 |
| 17 | Target suppression of connexin43 in ovinereimplantation embryos by RNA interference using double-strandedRNA显示文摘 | Yan Zhen Ma Yuzhen | 2010 | Asian-australasian journal of animal sciences2010，23，4： | 1 |
| 18 | A prolonged dry mid- Holocene climate revealed by pollen and diatom re- cords from Lake Ugii Nuur in central Mongolia 显示文摘 | Wang Wei Ma Yuzhen Feng Zhaodong | 2011 | Quater- nary International2011，229，： | 1 |
| 19 | Immunoglobulin and complement complexein blood following infection with human immunodeficiency virus typel 显示文摘 | PengXX Wainberg MA Tao Yuzhen | 1996 | Clin Diagn Lab Immunol1996，3，： | 1 |
| 20 | Palaeolake and palaeoenvironment between 42 and 18 ka BP in Tengger Desert, NW China 显示文摘 | ZHANG Hucai MA Yuzhen PENG Jinlan | 2002 | Chinese Science Bulletin2002，47，24： | 1 |
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