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| 1 | Response of runoff in the headwater region of the Yellow River to climate change and its sensitivity analysis显示文摘在到气候变化和它的敏感的黄河的 headwater 区域的流量的反应在时期期间在四个水文学车站和十个气象站基于测量数据被分析 19592008。结果显示在这个区域的温度的那个变化与全球温暖和在在这个区域的每个分区的温度一直在介绍的年度一般水准的变化有一种明显的相应关系过去的 50 年里的一个变动、升起的状态。因为不同地理位置和环境的影响,然而,降水的变化在总体上生产流量的区域一直在介绍的年度降水的各种各样的区域,和变化是比在这个区域的温度的变化更复杂的过去的 50 年里的一个变动、减少的状态。并且在这个区域在流量和降水和温度之间有一种显著非线性的相互关系。因为,自从 1990,在这个区域的流量连续地一直在减少降水总体上生产流量的区域显然减少,年度平均温度连续地升起。总体上,当在在 Jimai 上面的分区的流量相应地在在这个区域的其它比那对温度变化更敏感时,在黄河的 headwater 区域的每个分区的流量对降水变化相当敏感。 | LAN Yongchao ZHAO Guohui ZHANG Yaonan WEN Jun HU Xinglin LIU Jinqi GU Minglin CHANG Junjie MA Jianhua | 2010 | Journal of Geographical Sciences2010，20，6： | 20 |
| 2 | InvesInvestigation of the Effects of Airfoil-probes on the Aerodynamic Performance of an Axial Compressor显示文摘In order to investigate the effects of the airfoil-probes on the aerodynamic performance of an axial compressor,a numerical simulation of 3D flow field is performed in a 1.5-stage axial compressor with airfoil-probes installed at the stator leading-edge(LE).The airfoil-probes have a negative influence on the compressor aerodynamic performance at all operating points.A streamwise vortex is induced by the airfoil-probe along both sides of the blade.At the mid-operating point,the vortex is notable along the pressure side and is relatively small along the suction side(SS).At the near-stall point,the vortex is slightly suppressed in the pressure surface(PS),but becomes remarkable in the suction side.A small local-separation is induced by the interactions between the vortex and the end-wall boundary layer in the corner region near the hub.That the positive pitch angle of the airfoil-probe at 6.5% span is about 15° plays an important role in the vortex evolution near the hub,which causes the fact that the airfoil-probe near the hub has the largest effects among the four airfoil-probes.In order to get a further understanding of the vortex evolution in the stator in the numerical simulation,a flow visualization experiment in a water tunnel is performed.The flow visualization results give a deep insight into the evolution of the vortex induced by the airfoil-probe. | HE Xiang MA Hongwei REN Minglin XIANG Honghui | 2012 | Chinese Journal of Aeronautics2012，25，4： | 8 |
| 3 | Highly reactive multilayer-assembled TiO2 coating on electrospun polymer nanofibers显示文摘 | Jung Ah Lee Kevin C Krogman Ma Minglin | 2009 | Adv Mater2009，21，12： | 1 |
| 4 | Superhydrophobic surfaces显示文摘 | MA Minglin RANDAL M Hill | 2006 | Current Opinion in Colloid & Interface Science2006，11，： | 1 |
| 5 | Designing superoleophobie surfaces 显示文摘 | Tuteja Anish Choi Wonjae Ma Minglin | 2007 | Science2007，318，： | 1 |
| 6 | Designing superoleophobic surfaces显示文摘 | Tuteja Anish Choi Wonjae Ma Minglin | | 0，，： | 1 |
| 7 | Superhydrophobic surfaces显示文摘 | Minglin Ma Randal M. Hill | 2006 | Current Opinion in Colloid & Interface Science2006，，4： | 1 |
| 8 | Superhydrophobic surfaces 显示文摘 | Ma Minglin Hill Randal M | 2006 | Current Opinion in Colloid & Interface Science2006，11，4： | 1 |
| 9 | Superhydrophobic surfaces显示文摘 | MA MINGLIN HILL R M | 2006 | Current Opinion in Colloid & Interface Science2006，11，4： | 1 |
| 10 | Superhydrophobic surfaces 显示文摘 | Minglin Ma Hill R M | 2006 | Current Opinion in Colloid & Interface Science2006，，11： | 1 |
| 11 | Designing superoleophobic surfaces显示文摘 | Tuteja Anish Choi Wonjae Ma Minglin | 2007 | Science2007，318，： | 1 |
| 12 | 显示文摘 | Ma Minglin Mao Yu Gupta Malancha | 2005 | Macromolecules2005，38，： | 1 |
| 13 | Electrospun poly(styrene-block-dimethylsiloxane) block eopoly- mer fibers exhibiting superhydrophobicity 显示文摘 | MA Minglin HILL R M LOWERY l L | 2005 | Langmuir2005，21，12： | 1 |
| 14 | Superhydrophobic fabrics produced by electrospinning and chemical wapor deposition显示文摘 | Ma Minglin Mao Yu Cupta Malancha | | 0，，23： | 1 |
| 15 | 显示文摘 | Minglin Ma Randal M Hill | 2006 | Current Opinion inColloidInterface Science2006，11，4： | 1 |
| 16 | Nanoparticle enhanced combination therapy for stem-like progenitors defined by single-cell transcriptomics in chemotherapy-resistant osteosarcoma显示文摘The adaptation of osteosarcoma cells to therapeutic pressure impedes the efficacy of chemotherapy for osteosarcoma.However,the characteristics and cellular organization of therapy-resistant cells in osteosarcoma tumors remain elusive.Here,we utilized single-cell transcriptomics to systematically map the cell-type-specific gene expression in a chemotherapy-resistant osteosarcoma tumor.Our data demonstrated the VEGFR2-JMJD3-abundant subsets as quiescent stem-like cells,thereby establishing the hierarchy of therapy-resistant actively cycling progenitor pools(JMJD3-abundant)in osteosarcoma.VEGFR2 inhibitor and JMJD3 inhibitor synergistically impeded osteosarcoma cell propagation and tumor growth.Although osteosarcoma cells are predisposed to apoptosis induced by the synergistic therapy through activation of the CHOP pro-apoptotic factor via the endoplasmic reticulum(ER)stress,the stem-like/progenitor cells exhibit an adaptive response,leading to their survival.Reduction in cellular glutathione levels in stem-like/progenitor cells caused by the treatment with a glutathione synthesis inhibitor increases ER stress-induced apoptosis.Importantly,the marked therapeutic improvement of synergistic therapy against stem-like/progenitor cells was achieved by using glutathione-scavenging nanoparticles,which can load and release the drug pair effectively.Overall,our study provides a framework for understanding glutathione signaling as one of the therapeutic vulnerabilities of stem-like/progenitor cells.Broadly,these findings revealed a promising arsenal by encapsulating glutathione-scavenging nanoparticles with co-targeting VEGFR2 and JMJD3 to eradicate chemotherapy-resistant osteosarcoma. | Li Wang Xiaojia Huang Xinru You Tianqi Yi Bing Lu Jiali Liu Guohao Lu Minglin Ma Changye Zou Jun Wu Wei Zhao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 1 |
| 17 | An adhesive and resilient hydrogel for the sealing and treatment of gastric perforation显示文摘Adhesive hydrogels have been recently proposed as a potential option to seal and treat gastric perforation(GP)which causes high mortality despite advancements in surgical treatments.However,to be effective,the hydrogels must have sufficient tissue adhesiveness,tough mechanical property,tunable biodegradability and ideally are easy to apply and form.Herein,we report an adhesive and resilient hydrogel for the sealing and treatment of gastric perforation.The hydrogel consists of a bioactive,transglutaminase(TG)-crosslinked gelatin network and a dynamic,borate-crosslinked poly-N-[Tris(hydroxymethyl)methyl]acrylamide(PTH)network.The hydrogel can be formed in situ,facilitating easy delivery to the GP and allowing for precise sealing of the defects.In vivo experiments,using a perforated stomach mouse model,shows that the adhesive hydrogel plug effectively seals GP defects and promotes gastric mucosa regeneration.Overall,this hydrogel represents a promising biomaterial for GP treatment. | Jing Chen Julia S.Caserto Ida Ang Kaavian Shariati James Webb Bo Wang Xi Wang Nikolaos Bouklas Minglin Ma | 2022 | Bioactive Materials2022，7，8： | 0 |
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