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| 1 | High-resolution geochemistry records of climate changes since late-glacial from Dajiuhu peat in Shennongjia Mountains,Central China显示文摘A peat core with depths of 297 cm was obtained from the Dajiuhu Basin(31°29′27″N,109°59′45″E,1760 m)in Hubei Province,Central China.10 AMS ages provide a time control and reveal that this core spans the past about 16.0 kaBP(calibrated age)(1 4C age:13.3 kaBP).Multi-proxy indexes analysis of geochemistry shows the following character of climate and environmental changes since about 16 kaBP:(1) The climate during the late-glacial period was cold and wet as a whole,but fluctuated continually.11.4- 12.6 cal.kaBP,12.6-15.2 cal.kaBP and 15.2-16 kaBP were corresponding respectively to the Younger Drays,Bφlling-Allerφd Warm Period and the Oldest Drays.(2)Inheriting the some climate characteristics of the late-glacial,the climate during the early-Holocene was wet and temperature increased gradually,during which an obvious dry event around 10.6 cal.kaB appeared.(3)The climate during the mid-Holocene was genarally warm and wet.During 9.2-7.5 kaBP,temperature increased gradually, precipitation was less comparatively and the 8.2 kaBP cold event which might be representative in the globe was reflected markedly.Then,multi-proxy records were relatively stable during 6.7-4.2 kaBP, which shows the best water and thermal condition in the Holocene Optimum.(4)Around 4.2 kaBP,the climate and environment transform from warm and wet to cool and dry,which may result in the collapse of the Neolithic Culture and midwifery the civilization of Xia Dynasty in this region.After 0.9 kaBP,the climate turned cool and wet.Climate and environmental changes archived in Dajiuhu peat respond to the global changes since the late-glacial period and can be contrasted to the changes recorded in other high-resolution archives from the East Asia Monsoon region,which take on the variety model that the monsoon strengthened abruptly after the late-glacial,was strong during the early Holocene,subse- quently declined and became weak after the middle Holocene with dry climate.According to our analysis,the driving mechanism should be the response of solar radiation changes in the East Asia Monsoon region at middle latitudes. | MA ChunMei ZHU Cheng ZHENG ChaoGui WU ChunLin GUAN Yong ZHAO ZhiPing HUANG LinYan HUANG Run | 2008 | Chinese Science Bulletin2008，53，S1： | 19 |
| 2 | Radiosensitization of human pancreatic cancer by piperlongumine analogues显示文摘Radiotherapy is commonly used to treat advanced pancreatic cancers and can improve survival by2 months in combination with gemcitabine.However,prognosis and survival improvement remain unsatisfactory,and effective therapies are urgently needed.Piperlongumine has been demonstrated to have therapeutic potentials against various cancers.In this study,we synthesized a series of piperlongumine derivatives and provided evidence that piperlongumine derivatives could be used as effective radiosensitizers in pancreatic cancer.Two compounds enhanced the radiosensitivity of Panc-1 and SW1990 cells.In a pancreatic bi-flank xenograft tumor model,they significantly inhibited tumor growth.Piperlongumine derivatives could induce reactive oxygen species(ROS)expression and regulate the Keapl-Nrf2 protective pathway with enhancement of radiation-induced DNA damage,G2/M-phase cell cycle arrest,and apoptosis.Collectively,our data offer a proof of concept for the use of piperlongumine derivatives as a novel class of radiosensitizers for the treatment of pancreatic cancer. | Hao Ma Yuelin Wu Wannian Zhang Huojun Zhang Zhenyuan Miao Chunlin Zhuang | 2021 | Chinese Chemical Letters2021，32，3： | 4 |
| 3 | Gut microbiota contributes to the development of endometrial glands in gilts during the ovary-dependent period显示文摘Background:The hyper-prolificacy Meishan gilts achieved a superior endometrial gland development(EGD)than white crossbred gilts during the ovary-independent period(before 60 d of age).Then,the EGD continues under the management of ovary-derived steroid hormones that regulated by gut microbiota(after 60 d of age).However,whether Meishan gilts’superiority in EGD lasting to the ovary-dependent period(after 60 d of age)and the role of gut microbiota in this period both remain unclear.Methods:Meishan gilts and Landrace x Yorkshire(LxY)gilts were raised under the same housing and feeding conditions until sexual maturity and then we compared their EGD and gut microbiota.Meanwhile,we transplanted fecal microbiota from Meishan gilts to L×Y gilts to explore the role of gut microbiota in EGD.We sampled plasma every 3 weeks and collected the uterus,ovary,liver,and rectal feces after the sacrifice.We then determined the hormone concentrations and expressions of the EGD-related genes.We also profiled the gut microbiota using 16S rDNA sequencing and metabolites of plasma and liver tissue using untargeted metabolomics.Finally,the correlation analysis and significant test was conducted between FMT-shifted gut microbes and EGD-related indices.Results:Meishan gilts have larger endometrial gland area(P<0.001),longer uterine horn length(P<0.01)but lighter uterine horn weight(P<0.05),a distinctive gut microbiota compared with L×Y gilts.Fecal microbiota transplantation(FMT)increased endometrial gland area(P<0.01).FMT markedly shifted the metabolite profiles of both liver and plasma,and these differential metabolites enriched in steroid hormone biosynthesis pathway.FMT increased estradiol and insulin-like growth factor 1 but decreased progesterone dynamically.FMT also increased the expression of the EGD-related genes estrogen receptor 1 gene,epithelial cadherin,and forkhead box protein A2.There is a significant correlation between FMT-shifted gut microbes and EGD-related indices.Conclusion:Sexually matured Meishan gilts achieved a superior EGD than LxY gilts.Meanwhile,gut microbiota contribute to the EGD potentially via regulating of steroid hormones during the ovary-dependent period. | Baoyang Xu Wenxia Qin Yiqin Yan Yimei Tang Shuyi Zhou Juncheng Huang Chunlin Xie Libao Ma Xianghua Yan | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 4 |
| 4 | Effects of magnesium on the performance of sows and their piglets显示文摘The objective of this study was to evaluate the effects of supplemental magnesium(Mg) on the performance of gilts and parity 3 sows and their piglets.Fifty-six gilts(Trial 1) and 56 sows(Trial 2) were assigned to one of 4treatments according to their mating weight,respectively.The treatments comprised corn-soybean meal based gestation and lactation diets(0.21%magnesium) supplemented with 0,0.015,0.03,or 0.045%Mg from mating until weaning.The results showed that magnesium supplementation significantly(P < 0.05) reduced the weaning to estrus interval in both gilts and sows.There were significant effects(P < 0.05) of supplemental magnesium on the total number of piglets born,born alive and weaned in sows.In late gestation and lactation,the digestibility of crude fiber(quadratic effects,P< 0.05),and crude protein(P< 0.05),were significantly influenced by magnesium in gilts and sows,respectively.There were differences among the 4 groups in terms of the apparent digestibility of dry matter and crude fiber in sows(P< 0.05) during both early and late gestation.The apparent digestibility of gross energy was increased for sows in late gestation(P< 0.05),and lactation(quadratic effects,P< 0.05).At farrowing and weaning,serum prolactin levels and alkaline phosphate activities linearly increased in sows as the Mg supplementation increased(P < 0.05).Serum Mg of sows at farrowing and serum urea nitrogen of sows at weaning was significantly influenced by Mg supplementation(P< 0.05).The Mg concentration in sow colostrum and the serum of their piglets were increased by supplemental magnesium(P < 0.05).In addition,growth hormone levels were linearly elevated(P< 0.05) in the serum of piglets suckling sows.Our data demonstrated that supplemental magnesium has the potential to improve the reproduction performance of sows,and the suitable supplemental dose ranged from 0.015%to 0.03%. | Jianjun Zang Jingshu Chen Ji Tian Aina Wang Hong Liu Shengdi Hu Xiangrong Che Yongxi Ma Junjun Wang Chunlin Wang Guanghua Du Xi Ma | 2015 | Journal of Animal Science and Biotechnology2015，6，1： | 3 |
| 5 | Texture Characteristics of Thin Grain Oriented Silicon Steel Sheet Produced by Cross Shear Rolling显示文摘Commercial grain oriented silicon steel was cold rolled to thickness from 0.06 to 0.10 mm by cross shear rolling, then annealed in vacuum or a hydrogen atmosphere furnace. Deformation textures of the sheets were researched by ODF method and reverse pole figure quantitative analyses. The results indicate that: in the condition of the cross shear rolling, the deformation texture of rolled sheet is generally similar to that of conventional rolled sheet, however, the texture distribution through the thickness is asymmetrical. With mismatch speed ratio increasing, the amount of Goss texture increases. With reduction ratio increasing, the intensity of γ-fiber becomes strong. | Xiuhua GAO, Kemin QI, Renlong LI, Chunlin QIU, Bo MA and Guangrun BAI (Department of Metal Forming, Northeastern University, Shenyang 110006, China) | 2000 | Journal of Materials Science & Technology2000，16，2： | 2 |
| 6 | Carboxyl groups trigger the activity of carbon nanotube catalysts for the oxygen reduction reaction and agar conversion显示文摘臭氧处理是到有象 carboxyl,酚和内酯一样的各种各样的氧功能的商业多围的碳 nanotubes (CNT ) 组织的 functionalize 的一条普通的路,以便提高他们的组织上性质和化学活动。以便详细说明每个功能的组的效果,我们相关有每个组的表面密度的活动,并且发现 carboxyl 组在二重要催化反应起一个枢轴的作用,也就是电气化学的氧减小反应( ORR )和到 5-hydroxymethylfurfural ( HMF )的琼脂变换。在这些过程期间,当改进的孔允许反应物和产品的有效散开时,吸水的表面为反应底层提供一种强壮的亲密关系。而且,为琼脂变换的 functionalized CNT 的活动在反应的九个周期期间仍然保持几乎未改变。这个工作为为电气化学的 ORR 和琼脂变换反应改进 CNT 的活动加亮策略,也是的 carboxyl 富有的 CNT 的有希望的应用生产高纯净的 HMFan 的稳固的酸催化剂重要化学中介。 | Yexin Zhang Chunlin Chen Lixia Peng Zhongsen Ma Yajie Zhang Hengheng Xia Aili Yang Lei Wang Dang Sheng Su Jian Zhang | 2015 | Nano Research2015，8，2： | 2 |
| 7 | Integrated analysis of multi-tissues lipidome and gut microbiome reveals microbiota-induced shifts on lipid metabolism in pigs显示文摘Lipid metabolism is very important for meat quality in pigs.Accumulating evidence shows that gut microbiota can contribute to this physiological process.However,the gut microbiota that function in lipid metabolism and adipogenesis remains unclear.Here,we compared the characteristics of fat deposition and gut microbial community between Laiwu pigs and Duroc(LandraceYorkshire)(DLY)pigs.Fecal microbiota transplantation(FMT)was performed to determine the possible impact of gut microbiota on lipid metabolism in pigs.An integrated analysis of the gut microbiome and lipidome of the small intestine,plasma,and liver was conducted to investigate the effects of FMT on host lipid metabolism.The comparative analysis of the gut microbiome showed higher abundance of Bacteroidetes(P=0.0018)while lower abundance of Firmicutes(P=0.012)in Laiwu pigs,and the microbial composition can be transferred from Laiwu pigs into DLY pigs.Transmission electron microscope and Oil red-O staining were performed to analyze the effects of FMT on lipid deposition in liver,the main target organ for lipid metabolism.The results showed that FMT significantly increased the number of lipid droplets(P=0.0035)and lipid accumulation(P=0.0026)in liver.Furthermore,integrated multi-tissues lipidome analysis demonstrated that the fatty acyls and glycerophospholipids were significantly increased(P<0.01)in intestine and liver,while glycerolipids and fatty acyls were reduced(P<0.01)in plasma.In the small intestine,FMT increased(P<0.01)the relative abundance of polyketides and prenol lipids but reduced(P<0.01)the saccharolipids.Correlation analysis revealed the potential interactions between microbiota and lipid metabolites.Together,our results indicated that the gut microbiota may regulate the lipid metabolism and enhance the accumulation of lipid droplets in the liver of pigs. | Chunlin Xie Xiaoyan Zhu Baoyang Xu Yaorong Niu Xuelei Zhang Libao Ma Xianghua Yan | 2022 | Animal Nutrition2022，，3： | 2 |
| 8 | Temperature rise and flow of Zr-based bulk metallic glasses under high shearing stress显示文摘Deformation of the bulk metallic glasses (BMGs) and the creation and propagation of the shear bands are closely interconnected.Shearing force was loaded on Zr 41.2 Ti 13.8 Cu 12.5 Ni 10.0 Be 22.5 (Vit.1) BMGs by cutting during the turning of the BMG rod.The temperature rise of alloy on the shear bands was calculated and the result showed that it could reach the temperature of the super-cooled liquid zone or exceed the melting point.The temperature rise caused viscous fluid flow and brought about the deformation of BMGs.This suggested that the deformation of BMGs was derived,at least to some extent,from the adiabatic shear temperature rise. | ZHANG WeiGuo MA MingZhen SONG AiJun LIANG ShunXing HAO QiuHong TAN ChunLin JING Qin LIU RiPing | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，11： | 2 |
| 9 | Multi-omics analysis reveals gut microbiota-induced intramuscular fatdeposition via regulating expression of lipogenesis-associated genes显示文摘The gut microbiome has great effects on the digestion, absorption, and metabolism of lipids. However,the microbiota composition that can alter the fat deposition and the meat quality of pigs remains unclear.Here, we used Laiwu (LW) pigs (a native Chinese breed with higher intramuscular fat) compared withcommercial crossbreed Duroc×(Landrace×Yorkshire) (DLY) pigs to investigate the effects of microbiotaon meat quality, especially in intramuscular fat content. A total of 32 DLY piglets were randomly allottedto 4 groups and transplanted with fecal microbiota from healthy LW pigs. The results indicated that thehigh dose of fecal microbiota transplantation (HFMT) selectively enhanced fat deposition in longissimusdorsi (P < 0.05) but decreased backfat thickness (P < 0.05) compared with control group. HFMT significantlyaltered meat color and increased feed conversation ratio (P < 0.05). Furthermore, the multi-omicsanalysis revealed that Bacteroides uniformis, Sphaerochaeta globosa, Hydrogenoanaerobacterium saccharovorans,and Pyramidobacter piscolens are the core species which can regulate lipid deposition. A total of140 male SPF C57BL/6j mice were randomly allotted into 7 groups and administrated with these 4 microbesalone or consortium to validate the relationships between microbiota and lipid deposition.Inoculating the bacterial consortium into mice increased intramuscular fat content (P < 0.05) comparedwith control mice. Increased expressions of lipogenesis-associated genes including cluster of differentiation36 (Cd36), diacylglycerol O-acyltransferase 2 (Dgat2), and fatty acid synthase (FASN) wereobserved in skeletal muscle in the mice with mixed bacteria compared with control mice. Together, ourresults suggest that the gut microbiota may play an important role in regulating the lipid deposition in the muscle of pigs and mice. | Chunlin Xie Junyong Teng Xinkai Wang Baoyang Xu Yaorong Niu Libao Ma Xianghua Yan | 2022 | Animal Nutrition2022，，2： | 2 |
| 10 | Structural diversity of di and triorganotin complexes with 4-sulfanylbenzoic acid:Supramolecular structures involving intermolecular Sn …O,O-H … O or C-H …X(X = O or S)interactions显示文摘 | MA CHUNLIN ZHANG QINGFU ZHANG RUFEN | 2005 | J Organomet Chem2005，690，： | 1 |
| 11 | Syntheses and crys- tal structures of di-and triorganotin derivatives with 2,5- dimercapto-1,3,4-thiodia zole 显示文摘 | Ma Chunlin Li Feng Jiang Qin | 2004 | Journal of Organome- tallic Chemistry2004，689，： | 1 |
| 12 | Fat deposition deficiency is critical for the high mortality of pre-weanling newborn piglets显示文摘Background: The high mortality of pre-weanling piglets is a dominant challenge which severely restricts the development of pig industry. A number of factors including nutrients imbalance and temperature variation during postnatal period of piglets have been reported to closely associated with the high mortality of postnatal piglets.This study aims to find out the relationship between fat deposition and survival of newborn piglets.Results: There were no differences in organ coefficient and bone density between the surviving and dead piglets(P > 0.05). The body weight and the fat deposition in the dead piglets were lower than the live individuals(P < 0.05).Consistently, the average sizes of white adipocytes in back and abdominal adipose tissues of dead piglets were smaller than the survivals(P < 0.05). The protein expression levels of adipocyte differentiation markers PPARγ and C/EBPα in the back and abdominal adipose tissues were lower in dead piglets compared to live piglets. The mRNA expressions of thermogenic markers PGC1α and PRDM16 in adipose tissues were decreased in the dead piglets(P < 0.05). The microarray of back fat samples from the surviving and dead piglets were conducted; two down-regulated genes namely AAMDC and CASTOR1 were identified from the dead piglets. According to quantitative real-time PCR(RT-PCR) analysis, the mRNA expression of AAMDC decreased, whereas CASTOR1 expression elevated in the dead piglets compared to the surviving piglets(P < 0.05).Conclusions: The fat deposition and adipocyte differentiation in the dead piglets are insufficient compared to the surviving piglets, which may attenuate the thermogenic ability of white adipose tissue(WAT). Our data indicate that fat deposition in newborn piglets is vital to their survival. | Ting He Long He Enen Gao Jinhua Hu Jianjun Zang Chunlin Wang Jinshan Zhao Xi Ma | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 1 |
| 13 | Competitive analysis of two special online device replacement problems显示文摘 | Xin Chunlin Ma Weimin Yang Lei | | 0，，2： | 1 |
| 14 | Proteomic analysis of the sea-island cotton roots infected by wilt pathogen Verticillium dahliae显示文摘 | Wang Fuxin Ma Yinping Yang Chunlin | 2011 | Proteomics2011，1，： | 1 |
| 15 | Comparison of BBFs Observed by Single and Multi Satellites显示文摘This paper,using the data of three Cluster satellites,compares the observations of Bursty Bulk Flow (BBF) by single satellite with those by multi satellites.The results indicate that there exists remarkable difference between observations of BBF by single satellite and multi satellites.The observations of BBF by a single satellite depend on its position relative to the flow channel.The difference is caused by the localization characteristics of fast flows in the plasma sheet,and can lead to diverging views about substorm and causal relations among substorm phenomena. | Cao Jinbin Cheng Chao Ma Yuduan Cai Chunlin | 2010 | 空间科学学报2010，30，4： | 1 |
| 16 | Self- assembly syntheses and crystal structures of triorganotin (IV) pyridinecarboxylate : 1 D poly- mers and a 42 - membered macrocycle 显示文摘 | Chunlin Ma Qianli Li Mengjie Guo | 2009 | Journal of Organometallic Chemistry2009，694，： | 1 |
| 17 | Upper Paleozoic total petroleum system and geological model of natural gas enrichment in Ordos Basin, NW China显示文摘Based on the analysis of Upper Paleozoic source rocks, source-reservoir-caprock assemblage, and gas accumulation characteristics in the Ordos Basin, the gas accumulation geological model of total petroleum system is determined. Then, taking the Carboniferous Benxi Formation and the Permian Taiyuan Formation and Shanxi Formation as examples, the main controlling factors of gas accumulation and enrichment are discussed, and the gas enrichment models of total petroleum system are established. The results show that the source rocks, faults and tight reservoirs and their mutual coupling relations control the distribution and enrichment of gas. Specifically, the distribution and hydrocarbon generation capacity of source rocks control the enrichment degree and distribution range of retained shale gas and tight gas in the source. The coupling between the hydrocarbon generation capacity of source rocks and the physical properties of tight reservoirs controls the distribution and sweet spot development of near-source tight gas in the basin center. The far-source tight gas in the basin margin is mainly controlled by the distribution of faults, and the distribution of inner-source, near-source and far-source gas is adjusted and reformed by faults. Generally, the Upper Paleozoic gas in the Ordos Basin is recognized in four enrichment models: inner-source coalbed gas and shale gas, inner-source tight sandstone gas, near-source tight gas, and far-source fault-transported gas. In the Ordos Basin, inner-source tight gas and near-source tight gas are the current focuses of exploration, and inner-source coalbed gas and shale gas and far-source gas will be important potential targets in the future. | JIANG Fujie JIA Chengzao PANG Xiongqi JIANG Lin ZHANG Chunlin MA Xingzhi QI Zhenguo CHEN Junqing PANG Hong HU Tao CHEN Dongxia | 2023 | Petroleum Exploration and Development2023，50，2： | 1 |
| 18 | Effect of aging on islet beta-cell function and its mechanisms in Wistar rats显示文摘 | Zhaoyan Gu Yingzhen Du Yu Liu Lichao Ma Lin Li Yanping Gong Hui Tian Chunlin Li | 2012 | AGE2012，，6： | 1 |
| 19 | Atomic origin of magnetic coupling of antiphase boundaries in magnetite thin films显示文摘Revealing the magnetic coupling nature of boundary defects is crucial for in-depth understanding of the behavior and properties of magnetic materials and devices.Here,magnetite(i.e.,Fe_(3)O_(4))thin films were grown epitaxially on(100)SrTiOsingle-crystal substrates by pulsed laser deposition.Atomic-scale scanning transmission electron microscopy characterizations reveal that three types of antiphase boundaries(APBs)are formed in the Fe_(3)O_(4)thin film.They are the(100)APB that is formed on the(100)plane with a crystal translation of(1/4)a[011^(-)],the typeⅠand typeⅡ(110)APBs that are both formed on the(110)plane with the same crystal translation of(1/4)a[101]but different terminated atomic planes.The typeⅠ(110)APB is terminated at the atomic plane with mixed tetrahedral-and octahedral-sites Fe atoms,the typeⅡ(110)APB is terminated at the octahedral-site Fe plane.First-principles calculations reveal that the(100)APB and the typeⅠ(110)APB tend to form the ferromagnetic coupling that will not decrease the spin polarization of Fe_(3)O_(4)films,while the typeⅡ(110)APB prefers to form the antiferromagnetic coupling that will degrade the magnetic properties.The magnetic coupling modes of the APBs are closely related to the Fe-O-Fe bond angles across the boundaries. | Chunyang Gao Yixiao Jiang Tingting Yao Ang Tao Xuexi Yan Xiang Li Chunlin Chen Xiu-Liang Ma Hengqiang Ye | 2022 | Journal of Materials Science & Technology2022，，12： | 1 |
| 20 | A study on particle filters for single-tone frequency tracking 显示文摘 | Ng W Ji Chunlin Ma W K ct al | 2009 | IEEE Transactions on Aero- space and Electronic Systems2009，45，5： | 1 |
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