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| 1 | Clinical analysis of intracranial germinoma's craniospinal irradiation using helical tomotherapy显示文摘Objective: To evaluate the short-term clinical outcomes of intracranial germinoma patients treated with craniospinal irradiation(CSI) using helical tomotherapy(HT) system in our center. Methods: Twenty-three patients who were treated with CSI in our center from January 2008 to July 2012 were collected, with an average age of 20. All of the patients' CSI used the HT system. The total doses were 27-36 Gy/15-20 F(1.5-2 Gy per fraction), and total local doses were 46-60 Gy/30-50 F(5 fractions per week). All female patients for CSI were treated with left-right parallel-opposed field irradiation to protect their ovarian functions. Median follow-up time was 30.9 months(range, 5-67 months). The SPSS19.0 software was used, and the overall survival(OS) was calculated using the Kaplan-Meier method.Results: Among 17 patients with assessable tumors, 9 cases(52.9%) were CR, 7 cases(41.2%) were PR, and 1 case(5.9%) was SD. Hematological toxicity was the severest side-effect occurred in the procedure of CSI. The level 1-4 acute leukopenia were 8.7%, 30.4%, 34.8% and 21.7% and the level 1-4 acute thrombopenia were 8.7%, 30.4%, 21.7% and 8.7%, respectively.Conclusions: For primary intracranial germinomas, HT can be used to implement CSI for simplifying radiotherapy procedures, improving radiotherapy accuracy, enhancing protection of peripheral organs at risk(ORA) and guaranteeing therapeutic effects. With the acceptable acute and long-term toxicity, CSI using HT in intracranial germinoma patients can be a safe and alternative mode. | Baolin Qu Lei Du Yurong Huang Wei Yu Boning Cai Shouping Xu Lin Ma | 2014 | Chinese Journal of Cancer Research2014，26，3： | 14 |
| 2 | Fast and compact dynamic data compression based on composite rigid body construction显示文摘3D dynamic datasets compression still poses two challenges. One is high time cost due to growing data and complex computation of compression algorithms. The other is low compression factor because of complex motions of dynamic scenes and unknown motion equations. In this paper, composite rigid body construction for fast and compact compression of 3D dynamic datasets is proposed to solve these two problems. It accelerates the compression with a fast rigid body decomposition based on disjoint union, and avoids serial searching, comparing and merging of the rigid body decomposition. To increase the compression factor,composite rigid body is introduced with consideration of motion consistency among rigid bodies at different time periods. The results of the experiments show that our algorithm compresses dynamic datasets quickly and achieves a high compression factor. | MA ZhiQiang WANG LiLi ZHANG BoNing KE Wei ZHAO QinPing | 2014 | Science China(Information Sciences)2014，57，11： | 2 |
| 3 | Effects of denosumab treatment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass显示文摘 | Bone HG Bolognese MA Yuen CK Kendler DL Miller PD Yang YC Grazette L San Martin J Gallagher JC | | 0，，： | 1 |
| 4 | Effects of denosumab treat- ment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass显示文摘 | Bone HG Bolognese MA Yuen CK | 2011 | The Jour- nal of Clinical Endocrinology & Metabolism2011，96，4： | 1 |
| 5 | Effects of denosumab on bone mineral density and bone turnover in postmenopausal women显示文摘 | BONE HG BOLOGNESE MA YUEN CK et ol | 2008 | J Clin Endocrinol Metab2008，93，6： | 1 |
| 6 | Effects of denosumab on bone mineral density and bone turnover in postmenopausal women 显示文摘 | Bone HG Bolognese MA Ynen CK | 2008 | J Clin Endocrinol Metab2008，93，6： | 1 |
| 7 | Model -based controller design for machine tool direct feed drives显示文摘 | Elfizy AT Bone GM Elbestawi MA | 2004 | International Journal of Machine Tools & Manufacture2004，44，： | 1 |
| 8 | Effects of deno- sumab on bone mineral density and bone turnover in postm-enopausal women 显示文摘 | Bone HG Bolognese MA Yuen CK | 2008 | J Clin Endocrinol Metab2008，93，： | 1 |
| 9 | Mechanisms ofquasi-preconsolidation stress development in clays: A rheologicalmodel显示文摘 | MA Boning Balasingam Muhunthan XIE Xinyu | 2014 | Soils and Foundations2014，54，3： | 1 |
| 10 | Occurrence of familial spastic paraplegia in only one of monozygous twins显示文摘 | Bone I Johnson RH Ferguson-Smith MA | 1976 | J Neurol Neurosurg Psychiatry1976，39，： | 1 |
| 11 | Effects of denosumab on bone mineral density and bone turnover in postmenopausal women显示文摘 | Bone HG Bolognese MA Yuen CK | 2008 | J Clin Endocrinol Metab2008，93，： | 1 |
| 12 | Effects of denosumab on bone mineral density and bone turnover in postmenopausal women 显示文摘 | Bone HG Bolognese MA Yuen CK | 2008 | J Clin Endocrinol Metab2008，93，： | 1 |
| 13 | Effects ofdenosumab on bone mineral density and hone turnover in postmenopausal women 显示文摘 | BONE HG BOLOGNESE MA YUEN CK | 2008 | J Clin Endocrinol Metab2008，93，6： | 1 |
| 14 | Effects of denosumab on bone mineral density and bone turnover in postmenopausal women显示文摘 | Bone HG Bolognese MA Yuen CK | 2008 | J Clin Endocrinol Metab2008，93，： | 1 |
| 15 | Effects of denosumab treatment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass显示文摘 | Bone HG Bolognese MA Yuen CK | 2011 | J Clin Endocrinol Metob2011，96，： | 1 |
| 16 | Single-cell transcriptomic analysis uncovers intratumoral heterogeneity and drug-tolerant persister in ALK-rearranged lung adenocarcinoma显示文摘Dear Editor,Non-small cell lung carcinoma(NSCLC)accounts for more than 85%of all lung cancers[1].Lung adenocarcinomas(ADCs)arising from never-smokers have been frequently found to be associated with oncogenic driver mutations,including anaplastic lymphoma kinase(ALK)rearrangement.Echinoderm microtubule-associated protein-like 4(EML4)is the most common fusion partner of the ALK gene[2].Tyrosine kinase inhibitors(TKIs)are currently the first-line treatment for advanced EML4-ALKrearranged lung ADC. | Hoi-Hin Kwok Huiyu Li Jiashuang Yang Junyang Deng Nerissa Chui-Mei Lee Timmy Wing-Kuk Au Alva Ko-Yung Sit Michael Kuan-Yew Hsin Stephanie Kwai-Yee Ma LydiaWai-Ting Cheung Luc Girard Junya Fujimoto Ignacio Ivan Wistuba Boning Gao John Dorrance Minna David Chi-Leung Lam | 2023 | Cancer Communications2023，43，8： | 0 |
| 17 | Clinical practice guidelines for full-cycle standardized management of bone health in breast cancer patients显示文摘Bone health management for breast cancer spans the entire cycle of patient care,including the prevention and treatment of bone loss caused by early breast cancer treatment,the adjuvant application of bone-modifying agents to improve prognosis,and the diagnosis and treatment of advanced bone metastases.Making good bone health management means formulating appropriate treatment strategies and dealing with adverse drug reactions,and will help to improve patients'quality of life and survival rates.The Breast Cancer Expert Committee of the National Cancer Center for Quality Control organized relevant experts to conduct an in-depth discussion on the full-cycle management of breast cancer bone health based on evidence-based medicine,and put forward reasonable suggestions to guide clinicians to better deal with health issues in bone health clinics. | Committee of Full-cycle Standardized Management of Bone Health in Breast Cancer Patients Fei Ma | 2024 | Cancer Innovation2024，3，1： | 0 |
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