| 1 | Multiscale mechanobiology modeling for surgery assessment显示文摘This paper discusses some of the concept of mod-eling surgery outcome. It is also an attempt to offer a roadmap for progress. This paper may serve as a common groundof discussion for both communities i.e surgeons and com-putational scientist in its broadest sense. Predicting surgeryoutcome is a very difficult task. All patients are different,and multiple factors such as genetic, or environment con-ditions plays a role. The difficulty is to construct modelsthat are complex enough to address some of these significantmultiscale elements and simple enough to be used in clini-cal conditions and calibrated on patient data. We will pro-vide a multilevel progressive approach inspired by two ap-plications in surgery that we have been working on. One isabout vein graft adaptation after a transplantation, the otheris the recovery of cosmesis outcome after a breast lumpec-tomy. This work, that is still very much in progress, mayteach us some lessons. We are convinced that the digital rev-olution that is transforming the working environment of thesurgeon makes closer collaboration between surgeons andcomputational scientist unavoidable. We believe that 'com-putational surgery' will allow the community to develop pre-dictive model of the surgery outcome and greatprogresses insurgery procedures that goes far beyond the operating roomprocedural aspect. | M. Garbey B. L. Bass S. Berceli | 2012 | Acta Mechanica Sinica2012，28，4： | 0 |
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