|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Neurological complications of hematopoietic cell transplantation in children and adults显示文摘Hematopoietic cell transplantation(HCT) is widely performed for neoplastic and non-neoplastic diseases. HCT involves intravenous infusion of hematopoietic progenitor cells from human leukocyte antigen(HLA)-matched donor(allogeneic) or from the patient(autologous). Before HCT, the patient is prepared with high dose chemotherapy and/or radiotherapy to destroy residual malignant cells and to reduce immunologic resistance. After HCT, chemotherapy is used to prevent graft rejection and graft versus host disease(Gv HD). Neurological complications are related to the type of HCT, underlying disease, toxicity of the conditioning regimens, immunosuppression caused by conditioning regimens, vascular complications generated by thrombocytopenia and/or coagulopathy, Gv HD and inappropriate immune response. In this review, neurological complications are presented according to time of onset after HCT:(1) early complications(in the first month)-related to harvesting of stem cells, during conditioning(drug toxicity, posterior reversible encephalopathy syndrome), related to pancytopenia,(2) intermediate phase complications(second to sixth month)-central nervous system infections caused by prolonged neutropenia and progressive multifocal leukoencephalopathy due to JC virus,(3) late phase complications(after sixth month)-neurological complications of Gv HD, second neoplasms and relapses of the original disease. | Adriana Octaviana Dulamea Ioana Gabriela Lupescu | 2018 | Neural Regeneration Research2018，13，6： | 3 |
| 2 | Hepatic Perfusion Disorders:Computer-tomograpghic and Magnetic Resonance Imaging显示文摘 | Lupescu IG Grasu M Capsa R | 2006 | J Gastrointestin Liver Dis2006，15，3： | 1 |
| 3 | Spiral Computed Tomography and Magnetic Resonance Angiography Evaluation in Budd-Chiari Syndrome显示文摘 | Lupescu IG Dobromir C Popa GA | 2008 | J Gastrointestin Liver Dis2008，17，2： | 1 |
| 4 | The Todani classification for bile duct cysts : an overview 显示文摘 | Dumitrascu T Lupescu I Ionescu M | 2012 | Acta Chir Belg2012，112，5： | 1 |
| 5 | Hepatic Perfusion Disorders : Computer- tomograpghie and Magnetic Resonance Imaging显示文摘 | Lupescu IG Grasu M Capsa R | 2006 | J Gastrointestin Liver Dis2006，15，3： | 1 |
| 6 | Autologous mesenchymal stem cells applied on the pressure ulcers had produced a surprising outcome in a severe case of neuromyelitis optica显示文摘Recent studies provided evidence that mesenchymal stem cells(MSCs) have regenerative potential in cutaneous repair and profound immunomodulatory properties making them a candidate for therapy of neuroimmunologic diseases. Neuromyelitis optica(NMO) is an autoimmune, demyelinating central nervous system disorder characterized by a longitudinally extensive spinal cord lesion. A 46-year-old male diagnosed with NMO had relapses with paraplegia despite treatment and developed two stage IV pressure ulcers(PUs) on his legs. The patient consented for local application of autologous MSCs on PUs. MSCs isolated from the patient's bone marrow aspirate were multiplied in vitro during three passages and embedded in a tridimensional collagen-rich matrix which was applied on the PUs. Eight days after MSCs application the patient showed a progressive healing of PUs and improvement of disability. Two months later the patient was able to walk 20 m with bilateral assistance and one year later he started to walk without assistance. For 76 months the patient had no relapse and no adverse event was reported. The original method of local application of autologous BM-MSCs contributed to healing of PUs. For 6 years the patient was free of relapses and showed an improvement of disability. The association of cutaneous repair, sustained remission of NMO and improvement of disability might be explained by a promotion/optimization of recovery mechanisms in the central nervous system even if alternative hypothesis should be considered. Further studies are needed to assess the safety and efficacy of mesenchymal stem cells in NMO treatment. | Adriana Octaviana Dulamea Mirela-Patricia Sirbu-Boeti Coralia Bleotu Denisa Dragu Lucia Moldovan Ioana Lupescu Giancarlo Comi | 2015 | Neural Regeneration Research2015，10，11： | 1 |
| 7 | Spiral Computed Tomography and Magnetic Resonance Angiography Evaluation in Budd Chiari Syndrome显示文摘 | Lupescu IG Dobromir C Popa GA | 2008 | J Gastrointestin Liver Dis2008，17，2： | 1 |
| 8 | CT and MRI of acquired portal venous system anomalies 显示文摘 | Lupescu I Masala N Capsa R | 2006 | J Gastrointestin Liver Dis2006，15，4： | 1 |
| 9 | Continuous lumbar plexus block: Use of radiography to determine catheter tip location显示文摘 | DE BIASI P LUPESCU R BURGUN G | 2003 | Reg Anesth Pain Med2003，28，2： | 1 |
| 10 | Giant left atrium with calcified walls and thrombus in a patient with an old, normally func- tioning ball-in-cage mitral valve prosthesis 显示文摘 | Popescu BA Lupescu I Georgescu SA | 2010 | Circulation2010，122，： | 1 |
| 11 | Helical CT and diagnostic evaluation of cranio-facial fibrous dysplasia显示文摘 | Lupescu I Hermier M Georgescu SA | 2001 | J Radiol2001，82，1： | 1 |
| 12 | Computer tomographic evaluation of digestive tract non-hodgkin lymphomas显示文摘 | Lupescu IG Grasu M Goldis G | 2007 | J Gastrointestin Liver Dis2007，16，： | 1 |
| 13 | Phospholipase A2 activity?dependent stimulation of Ca2+ entry by human parvovirus B 19 capsid protein VPI显示文摘 | Lupescu A Bock CT Lang PA | 2006 | Virol2006，80，11： | 1 |
| 14 | Inhibition ofNa+/H+ exchanger activity by parvovirus BI9 protein NSI显示文摘 | Lupescu A Geiger C Zahir N | 2009 | Cell Physiol Biochem2009，23，13： | 1 |
| 15 | Hepatic Perfusion Disorders: Computer-tomograpghic and Magnetic Resonance Imaging显示文摘 | Lupescu IG Grasu M Capsa R | 2006 | Gastrointestin Liver Dis2006，15，3： | 1 |
| 16 | Hepatic perfusion disorders:computer-tomographic and magnetic resonance imaging显示文摘 | Lupescu IG Grasu M Capsa R | 2006 | J Gastrointestin Liver Dis2006，15，3： | 1 |
| 17 | Computer tomographic evaluation of digestive tract non - Hodgkin lymphomas 显示文摘 | Lupescu IG Grasu M Goldis G | 2007 | J Gastrointestin Liver Dis2007，16，3： | 1 |
| 18 | Electron Spectros- copy Studies of the Steel/Enamel Interface显示文摘 | Lupescu M B Maria Zaharescu Andrei A | | Materials Sci- ence and Engineering0，1997，232： | 1 |
| 19 | Induction of apoptotic ery- throcyte death by rotenone 显示文摘 | Lupescu A Jilani K Zbidah M | 2012 | Toxicology2012，300，3： | 1 |
| 20 | Spiral Computed tomography and magnetic resonance angiography evaluation Budd Chiari syndrome显示文摘 | Lupescu IG Dobromie C Popa GA | | 0，，02： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员