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| 1 | Aminoglycoside-induced and non-syndromic hearing loss is associated with the G7444A mutation in the mitochondrial COI/tRNA (Ser(UCN)) genes in two Chinese families显示文摘 | Zhu Y Qian YP Tang XW Wang JD Yang L Liao ZS Li RH Ji JZ Li ZY Chen JF Choo DI Lu JX Guan MX | 2006 | 中国生物学文摘2006，20，4： | 16 |
| 2 | Portal vein embolization by fine needle ethanol injection :experimental and clinicalstudies显示文摘AIM To improve the technique of intraportal embolization (PVE) therapy, a new embolic method, was devised and the safety, effectiveness and feasibility were evaluated. METHODS PVE with intraportal ethanol injection via a fine needle was performed in 28 normal dogs, 22 SD rats, and 24 cirrhotic SD rats. After PVE, portography, histological and functional alteration of the liver were evaluated in dogs and rats, and the changes in portal hemodynamics as well as hepatic anatomy were observed in rats. In the clinical study, PVE by ethanol injection was performed in 61 patients with hepatocellular carcinoma under the guidance of portoechography with intraportal injection of CO 2. The effect of PVE was evaluated by ultrasonography and laparotomy. RESULTS The effectiveness and toxicity were dependent on the dose of ethanol. In the dogs, 0 25*!mg/*!kg of ethanol caused incomplete embolization with least liver damage, while 1 0*!mg/*!kg induced complete embolization with a high mortality of 57 1% (4/*!7) due to respiratory arrest. The dose of 0 5*!mg/*!kg resulted in complete embolization with slight toxicity to the liver. In the rats, the survival rate was 100% in normal group but 40 9% in cirrhotic models after ethanol injection by dose of 0 05*!mg/*!100*!g . PVE for cirrhotic rats with 0 03*!mg/*!100*!g of ethanol induced satisfactory embolization with significant hypertrophy in nonembolized lobes, and only slight damage to the hepatic parenchyma, and transient alteration in liver function, portal pressure and portal flow. In the clinical study, 12 cases with reverse portal flow were excluded judged by portoechography. Satisfactory embolization was gained in 90 2% (55/*!61) of the remaining patients determined by ultrasonography and surgery. All cases ran an uneventful postembolization course with no aberrant embolization. CONCLUSION PVE with intraportal ethanol injection of appropriate dosage via a fine needle is safe and effective and has several advantages comparing with transcatheter method. Portoechography is a mandatory approach for the prevention of aberrant embolization. | Lu MD Chen JW Xie XY Liang LJ Huang JF | 1999 | World Journal of Gastroenterology1999，5，6： | 15 |
| 3 | Orthotopic liver transplantation for fulminant hepatitis B显示文摘INTRODUCTION When fulminant hepatitis progress to deep encephalopathy,with stage Ⅲ or Ⅳ coma,it is commonly irreversible with a high mortality rate(80%-100%).Liver transplantation may be | He XS Huang JF Chen GH Fu Q Zhu XF Lu MQ Wang GD Guan XD | 2000 | World Journal of Gastroenterology2000，6，3： | 14 |
| 4 | Variation of summer monsoon intensity on the Loess Plateau of Central China during the last 130 000 a——Evidence from Rb and Sr distribution显示文摘THE loess-paleosol sequences from China potentially provide one of the best terrestrial records of past climates. Studies have shown that magnetic susceptibility in the sequences represents a proxy climate index closely related to changes of summer monsoon intensity. Some interpretative models have been advanced to account for these magnetic variations, although unanimity of opinion has not been reached. Recent geochemical studies of chemical | Chen, J Qiu, G Lu, HY Ji, JF | 1997 | Chinese Science Bulletin1997，42，6： | 4 |
| 5 | Rapamycin inhibits cell growth by induction of apoptosis on hepatocellular carcinoma cells in vitro显示文摘 | Zhang JF Liu JJ Lu MQ | 2007 | Transpl Immunol2007，17，3： | 1 |
| 6 | Function regions of the rat somatostatin gene显示文摘 | Lu M Miller C Habener JF | | 0，，： | 1 |
| 7 | Color Doppler velocity profile assessment of portal hemodynamics in cirrhotic patients with portal hypertension:correlation with esophageal variceal bleeding显示文摘 | Yin XY Lu MD Huang JF | | 0，，01： | 1 |
| 8 | Heart rate influence on incidence of cardiovascular disease among adults in China 显示文摘 | Mao Q Huang JF Lu X Chen J | 2010 | Int J Epidemiol2010，39，6： | 1 |
| 9 | Mutation spectrum of the CFTR gene in Taiwanese patients with congenital bilateral absence of the vas deferens显示文摘 | Wu CC Alper OM Lu JF | 2005 | Hum Reprod2005，20，9： | 1 |
| 10 | Antibody specific to thioredoxin re- ductase as a new biomarker for serodiagnosis of invasive aspergillosis in non-neutropenic patients 显示文摘 | Shi LN Li FQ Lu JF | 2012 | Clin Chimica Acta2012，413，910： | 1 |
| 11 | Color Doppler velocity pmfile assessment of portal hemodymamics in cirrhotic patients with portal hypertension : Correlation with esophageal variceal bleeding显示文摘 | Yin XY Lu MD Huang JF | 2001 | J Clin Ultrasound2001，29，1： | 1 |
| 12 | Midazolam phannacokineties and electroencephalographic changes in eisht Chinese men显示文摘 | Lu JF Wu MF Chen G | 1993 | Acta Pharmacologiea sinica1993，14，6： | 1 |
| 13 | The mechanism of kinetic ; inhibition of Cuinduced oxidation of low density lipoprotein by lanthanide ions 显示文摘 | Liu HM Cheng Y Lu JF | 2006 | Journal of Inorganic Biochemistry2006，100，7： | 1 |
| 14 | Role of ALDP (ABCD1) and mitochondria in X-linked adrenoleukodystrophy显示文摘 | McGuinness MC Lu JF Zhang HP | | 0，，02： | 1 |
| 15 | Heart rate influence on incidence of cardiovascular disease among adults in China显示文摘 | Mao Q Huang JF Lu X | 2010 | Int J EPid- emiology2010，39，6： | 1 |
| 16 | Current status of animal welfare and animal rights in China 显示文摘 | Lu JQ Bayne AK Wang JF | 2013 | Alternatives Lab Animals2013，41，： | 1 |
| 17 | New metric for object-oriented design显示文摘 | Chen JY Lu JF | 1993 | Information and Software Technology1993，35，4： | 1 |
| 18 | Culture Issues in using the SF-36 health survey in asia:results from taiwan显示文摘 | Tseng HM Lu JF Gandek B | 2003 | Health Qual Life Outcomes2003，261，1： | 1 |
| 19 | Purification,characterization and biological activity of an L-amino acid oxidase from Trimeresurus mucrosquamatus venom显示文摘 | Wei JF Wei Q Lu QM | 2003 | Shengwu Huaxue Yu Shengwu Wuli Xuebao2003，35，3： | 1 |
| 20 | Color Doppler velocity profile assessment of portal hemodynamics in cirrhotic patients with portal hypertension: correlation with esophageal variceal bleeding显示文摘 | Yin XY Lu ID Huang JF | 2001 | J Clin Ultrasound2001，29，1： | 1 |
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