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| 1 | A subunit vaccine based on rH-NS induces protection against Mycobacterium tuberculosis infection by inducing the Thl immune response and activating macrophaqes显示文摘 | Yuan Liu Suting Chen Bowen Pan Zhu Guan Zhenjun Yang Linfei Duan Hong Cai | 2016 | Acta Biochimica et Biophysica Sinica2016，48，10： | 2 |
| 2 | Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Monlb显示文摘 | Ximing Shao Yi Liu Qian Yu Zhihao Ding Wenyu Qian Lei Zhang Jianchao Zhang Nan Jiang Linfei Gui Zhiheng Xu Yang Hong Yifan Ma Yanjie Wei Xiaoqing Liu Changan Jiang Minyan Zhu Hongchang Li Huashun Li | 2016 | Cell Research2016，26，5： | 1 |
| 3 | pH-dependent deg- radation of acid orange Ⅱ by zero-valent iron in presence of oxygen 显示文摘 | He Chun Yang Jiannan Zhu Linfei | 2013 | Separation and Purification Technology2013，117，： | 1 |
| 4 | Liquid chromatography–tandem mass spectrometry for the determination of chrysoidine in yellow-fin tuna显示文摘 | Wenjun Gui Yong Xu Linfei Shou Guonian Zhu Yiping Ren | 2010 | Food Chemistry2010，，4： | 1 |
| 5 | coli 8099 using Ag/BiOI composite undervisible light irradia- tion显示文摘 | Zhu Linfei et aL Enhanced photocatalytic disinfection of E | 2012 | Appl Catal B: Environ2012，9159，： | 1 |
| 6 | Comprehensive safety evaluation method of surrounding rock during underground cavern construction显示文摘The deformation instability of surrounding rock and the collapse of rock blocks are two common failure modes observed during the construction of underground caverns.Therefore,a comprehensive safety evaluation method(CSEM)of surrounding rock for application during underground cavern construction is presented in this paper.The method can be used to evaluate the deformation stability of surrounding rock and predict the collapse of rock blocks,rapidly.First,a deformation stability prediction and evaluation method(DSPEM)for rock mass is established.It combines the safety evaluation method based on a deformation statistical analysis and an inverse deformation prediction method using measured deformation data of surrounding rock.This approach possesses the unique characteristics of complementary and mutual verification.In addition,a comprehensive early-warning index system(CWIS)for assessing the deformation stability of surrounding rock is presented.It consists of three types of warning indicators and three levels of warning values.The earlywarning values can be adjusted reasonably by the prediction correction method according to the measured displacements.For the collapse of rock blocks controlled by structural surfaces,a rapid prediction method of rock block collapse(RPMBC)based on the block theory is then presented.Finally,combining the DSPEM,RPMBC,and CWIS,the CSEM of surrounding rock for assessing the safety of cavern construction is established.It can provide technical support for decision making on the safety of surrounding rock during the construction of underground caverns. | Qingwen Ren Lei Xu Aixi Zhu Mingzhang Shan Linfei Zhang Jiafeng Gu Lei Shen | 2021 | Underground Space2021，6，1： | 0 |
| 7 | Effects of childhood trauma on aggressive behaviors andhippocampal function:the modulation of COMT haplotypes显示文摘Background:Aggression is a commonly hostile behavior linked to the hippocampal activity.Childhood trauma(CT)exposure has been associated with altered sensitization of the hypothalamic-pituitary-adrenal(HPA)axis and hippocampal volumewhich could increase violent aggressive behaviors.Additionally,Catechol-O-methyltransferase(COMT),the major dopamine metabolism enzyme,is impli-cated in stress responsivity,including aggression.Hence,CT exposure may affect aggression through the effect on the hippocampal function,which might also be modulated by the COMT variations.Objectives:This study examined whether both CT and haplotypes of COMT moderate hippocampal function and thus affect human aggressive behavior.Methods:We obtained bilateral hippocampal functional connectivity maps using resting state functional magnetic resonance imag-ing(MRI)data.COMT haplotype estimation was performed using Haploview 4.2 and PHASE 2.1.Then we constructed a moderated mediation model to study the effect of the CTQ×COMT on aggressive behavior.Results:Three major haplotypes were generated from thirteen single nucleotide polymorphisms(SNPs)within the COMT gene and formed three haplotypes corresponding to high,medium,and low enzymatic activity of COMT.The results showed interactive re-lationships between the Childhood Trauma Questionnaire(CTQ)and COMT with respect to the functional connectivity(FC)of the bilateral hippocampus(HIP)-orbital frontal cortex(OFC).Specifically,CT experience predicted lower negative HIP-OFC coupling in the APS and HPS haplotypes corresponding to the medium and high enzymatic activity of COMT,but greater FC in the LPS haplotypes corresponding to the low enzymatic activity.We also observed a conditional mediation effect of the right HIP-OFC coupling in the link between COMT and aggressive behavior that was moderated by CT experience.Conclusions:These results suggest that CT and COMT have a combined effect on aggressive behavior through hippocampal function.This mediation analysis sheds light on the influence of childhood experience on aggressive behavior in different genetic backgrounds. | Chao Wang Linfei Zhu Wenyu Zheng Hanyuzhu Peng Jiaojian Wang Yue Cui Bing Liu Tianzi Jiang | 2023 | Psychoradiology2023，3，1： | 0 |
| 8 | Shallowing interfacial carrier trap in transition metal dichalcogenide heterostructures with interlayer hybridization显示文摘With the unique properties,layered transition metal dichalcogenide(TMD)and its heterostructures exhibit great potential for applications in electronics.The electrical performance,e.g.,contact barrier and resistance to electrodes,of TMD heterostructure devices can be significantly tailored by employing the functional layers,called interlayer engineering.At the interface between different TMD layers,the dangling-bond states normally exist and act as traps against charge carrier flow.In this study,we propose a technique to suppress such carrier trap that uses enhanced interlayer hybridization to saturate dangling-bond states,as demonstrated in a strongly interlayer-coupled monolayer-bilayer PtSe2 heterostructure.The hybridization between the unsaturated states and the interlayer electronic states of PtSe2 significantly reduces the depth of carrier traps at the interface,as corroborated by our scanning tunnelling spectroscopic measurements and density functional theory calculations.The suppressed interfacial trap demonstrates that interlayer saturation may offer an efficient way to relay the charge flow at the interface of TMD heterostructures.Thus,this technique provides an effective way for optimizing the interface contact,the crucial issue exists in two-dimensional electronic community. | Xu Wu Jingsi Qiao Liwei Liu Yan Shao Zhongliu Liu Linfei Li Zhili Zhu Cong Wang Zhixin Hu Wei Ji Yeliang Wang Hongjun Gao | 2021 | Nano Research2021，14，5： | 0 |
| 9 | Knockdown of Nav1_5 inhibits cell proliferation,migration and invasion via Wnt/β-catenin signaling pathway in oral squamous cell carcinoma显示文摘Oral squamous cell carcinoma(OSCC)is a common type of malignant oral cancer that has a high recurrence rate.Voltage-gated sodium channel Nav1.5 was reported to be highly up-regulated in various types of cancers.However,the regulatory mechanism of Nav1.5 in cancers including OSCC still remains elusive.In this study,Nav1.5 was found to be highly expressed in OSCC tissues and cells.Through the analysis of clinical characteristics of patients,we found that the expression level of Nav1.5 was closely related to neutrophil-to-lymphocyte ratio,platelet-to-lymphocyte ratio,tumor-node-metastasis stage,and lymph node metastasis.Moreover,we found that Nav1.5 mainly located on the cell membrane as well as cytoplasm and knockdown of Nav1.5 promoted cell apoptosis and decreased proliferation in OSCC.Transwell assay results showed that knockdown of Nav1.5 effectively suppressed the migration and invasion in OSCC.In addition,knockdown of Nav1.5 was found to inhibit the protein and mRNA expression levels ofβ-catenin,cyclin D1,and C-Myc in the Wnt/βcatenin signaling pathway.In summary,these results indicated that Nav1.5 may be involved in the progression of OSCC through the Wnt/βcatenin signaling pathway. | Xiaoli Xu Yongzheng Dai Linfei Feng Hongli Zhang Yukun Hu Le Xu Xinwei Zhu Yong Jiang | 2020 | Acta Biochimica et Biophysica Sinica2020，52，5： | 0 |
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