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| 1 | 氟西汀促进卒中后神经功能康复机制的研究进展显示文摘氟西汀(Fluoxetine)是一种高特异性,高选择性的5-羟色胺(5-HT)再摄取抑制剂(Selective reuptake inhibitors,SS-RIs),临床上主要用于治疗抑郁性精神障碍。传统抑郁症的"单胺学说"认为,抑郁的发生主要与单胺类神经递质如5-HT及去甲肾上腺素(NE)水平低下有关。 | 刘霞 Djung Lilya Wati 李雷雷 房亮 牟君 谢鹏 | 2010 | 医学教育探索2010,9,11: | 4 |
| 2 | Facial morphology and oc- clusion at the stage of early mixed dentition in cleft and lip and palate patients treated with delayed closure of the hardpalate显示文摘 | Friede H Moiler M Lilya J | 1987 | Suana Plast Reconstr Surg Hang Surg1987,21,: | 1 |
| 3 | Surface properties evolution of attapulgite by IGC analysis as a function of thermal treatment显示文摘 | Lilya Boudriche Rachel Calvet Boualem Hamdi Henri Balard | 2012 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2012,,: | 1 |
| 4 | 博尔纳病病毒与细胞内信号转导通路显示文摘博尔纳病病毒(Borna disease virus,BDV)是一种嗜神经性RNA病毒,可以在温血动物神经系统内形成非细胞溶解性持续感染。根据宿主种类及感染途径不同, | 刘霞 Djung Lilya Wati 谢鹏 | 2011 | 重庆医科大学学报2011,36,7: | 1 |
| 5 | 体外培养神经干细胞球的离散:一种安全有效的方法显示文摘目的:探讨一种安全有效地对体外培养神经干细胞球进行离散的方法。方法:采用常规胰蛋白酶消化、单纯巴斯德吸管吹打、滤网研磨、控制神经球体积的胰酶短时消化4种方法,比较其各自的离散效果和离散后细胞存活情况。结果:胰酶消化较长时间虽然可以得到单细胞但是细胞难以存活,单纯巴斯德吸管吹打不能完全离散神经球,不锈钢滤网研磨细胞损伤大,存活率低下,而采用控制神经球体积结合胰蛋白酶短时消化可以轻易获得单细胞并且细胞存活率明显高于其他方法(93.2%,P<0.05)。结论:控制神经球体积的胰酶短时消化法是离散神经干细胞球的一种安全有效的方法。 | 刘霞 Djung Lilya Wati 齐志国 李雷雷 房亮 谢鹏 | 2010 | 重庆医科大学学报2010,35,9: | 1 |
| 6 | Evidence that p53-mediated cell-cycle-arrest inhihits chemotherapeutic treatment of ovarian carcinomas显示文摘 | CARLOS S M LILYA M ERIN B D | 2007 | PLoS ONE2007,2,5: | 1 |
| 7 | Overexpression of miR-429 induces mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cells显示文摘 | Jing Chen Lijuan Wang Lilya V. Matyunina Christopher G. Hill John F. McDonald | 2010 | Gynecologic Oncology2010,,1: | 1 |
| 8 | 被裁后显示文摘2007年,在一家德国公司工作了两年之后,我跳槽进入了一家众人羡慕的企业——加拿大北方电信(以下简称北电)。 | Lilya | 2012 | 大学生2012,,20: | 0 |
| 9 | The carrot monoterpene synthase gene cluster on chromosome 4 harbours genes encoding flavour-associated sabinene synthases显示文摘In plants,low molecular weight terpenes produced by terpene synthases(TPS)contribute to multiple ecologically and economically important traits.The present study investigates a carrot terpene synthase gene cluster on chromosome 4 associated with volatile monoterpene production.Two carrot mutants,yellow and cola,which are contrasting in the content of low molecular weight terpenes,were crossed to develop an F2 mapping population.The mapping analysis revealed overlapping QTLs on chromosome 4 for sabinene,α-thujene,α-terpinene,γ-terpinene,terpinen-4-ol and 4-carene.The genomic region of this locus includes a cluster of five terpene synthase genes(DcTPS04,DcTPS26,DcTPS27,DcTPS54 and DcTPS55).DcTPS04 and DcTPS54 displayed genotype-and tissue-specific variation in gene expression.Based on the QTL mapping results and the gene expression patterns,DcTPS04 and DcTPS54 were selected for functional characterization.In vitro enzyme assays showed that DcTPS54 is a single-product enzyme catalysing the formation of sabinene,whereas DcTPS04 is a multiple-product terpene synthase producingα-terpineol as a major product and four additional products including sabinene,β-limonene,β-pinene and myrcene.Furthermore,we developed a functional molecular marker that could discriminate carrot genotypes with different sabinene content in a set of 85 accessions. | Sven Reichardt Holger Budahn Dominic Lamprecht David Riewe Detlef Ulrich Frank Dunemann Lilya Kopertekh | 2020 | Horticulture Research2020,7,1: | 0 |
| 10 | 博尔纳病病毒核蛋白调控神经干细胞存活增殖及ERK1/2信号通路的实验研究显示文摘目的观察博尔纳病病毒核蛋白(Borna disease virus p40,BDV p40)对大鼠海马源性神经干细胞(Neu-ral stem cells,NSCs)增殖、存活、分化及ERK1/2信号通路的影响,揭示BDV引起神经精神疾病的部分发病机制。方法(1)分别用pEGFP-N1-p40及pEGFP-N1质粒转染NSCs,观察转染效率并鉴定BDV p40在NSCs中的表达。(2)实验设置3组:未转染组、pEGFP-N1空转对照组及pEGFP-N1-p40转染组,用CCK-8试剂盒、BrdU摄入实验及免疫组化分别检测细胞存活、增殖及分化为神经元、星型胶质细胞、少突胶质细胞的比例的变化,并经Western Blot检测ERK1/2磷酸化的改变。结果 (1)成功建立表达BDV p40的NSCs模型;PCR结果显示只有pEGFP-N1-p40转染组细胞有BDV p40基因表达。(2)BDV p40抑制NSCs的存活、增殖,但对于转染后贴壁分化14 d时3组细胞分化为神经元、星型胶质细胞、少突胶质细胞的比例未见显著差异。Western Blot结果显示BDV p40下调了磷酸化ERK1/2在蛋白水平的表达。结论 BDV p40抑制NSCs的存活、增殖,但是对NSCs的分化方向没有明显的影响。BDV p40有可能通过下调磷酸化ERK1/2活性对NSCs的存活、增殖起抑制作用。 | 刘霞 DJUNG Lilya Wati 黄荣忠 张亮 王啸 杨柳 王明菊 谢鹏 | 2012 | 中国微生态学杂志2012,24,3: | 0 |
| 11 | 什么是密码Boole函数?显示文摘作为纯数学和应用数学以及计算机科学中研究的最基本的对象之一,在基础数学和数理逻辑的背景下,大约150年前,由英国数学家George Boole(布尔,1815-1864)引入了Boole函数这个概念在Boole的《思想的法则(The lawsof thought)》[3]中,他处理了逻辑的代数学(现在以Boole代数知名),为现代数字计算机电路的设计奠定了基础。 | Lilya Budaghyan Pantelimon Stanica 张翰文(译) 赵振江(校) | 2023 | 数学译林2023,42,1: | 0 |