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169篇 您的检索式:作者名="Koen S"
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1FDG-PET/CT response evaluation during EGFR-TKI treatment in patients with NSCLC显示文摘Over recent years,[18F]-fluorodeoxyglucose positron emission tomography acquired together with low dose computed tomography(FDG-PET/CT)has proven its role as a staging modality in patients with non-small cell lung cancer(NSCLC).The purpose of this review was to present the evidence to use FDG-PET/CT for response evaluation in patients with NSCLC,treated with epidermal growth factor receptor(EGFR)-tyrosine kinase inhibitors(TKI).All published articles from 1November 2003 to 1 November 2013 reporting on 18FFDG-PET response evaluation during EGFR-TKI treatment in patients with NSCLC were collected.In total 7studies,including data of 210 patients were eligible for analyses.Our report shows that FDG-PET/CT responseduring EGFR-TKI therapy has potential in targeted treatment for NSCLC.FDG-PET/CT response is associated with clinical and radiologic response and with survival.Furthermore FDG-PET/CT response monitoring can be performed as early as 1-2 wk after initiation of EGFR-TKI treatment.Patients with substantial decrease of metabolic activity during EGFR-TKI treatment will probably benefit from continued treatment.If metabolic response does not occur within the first weeks of EGFR-TKI treatment,patients may be spared(further)unnecessary toxicity of ineffective treatment.Refining FDG-PET response criteria may help the clinician to decide on continuation or discontinuation of targeted treatment.Matthijs H van Gool Tjeerd S Aukema Koen J Hartemink Renato A Valdés Olmos Houke M Klomp Harm van Tinteren 2014World Journal of Radiology2014,6,7:8
2Development of polymer–fullerene solar cells显示文摘Global efforts and synergetic interdisciplinary collaborations on solution-processed bulk-heterojunction polymer solar cells(PSCs or OPVs) made power conversion efficiencies over 10%possible.The rapid progress of the field is credited to the synthesis of a large number of novel polymers with specially tunable optoelectronic properties,a better control over the nano-morphology of photoactive blend layers,the introduction of various effective interfacial layers,new device architectures and a deeper understanding of device physics.We will review the pioneering materials for polymer-fullerene solar cells and trace the progress of concepts driving their development.We discuss the evolution of morphology control,interfacial layers and device structures fully exploring the potential of photoactive materials.In order to guide a further increase in power conversion efficiency of OPV,the current understanding of the process of free charge carrier generation and the origin of the photovoltage is summarized followed by a perspective on how to overcome the limitations for industrializing PSCs.Fengling Zhang Olle Ingans Yinhua Zhou Koen Vandewal 2016National Science Review2016,3,2:4
3The state principle-some general aspects of the relationship among the properties of systems 显示文摘Kline S J Koening F O 1957Journal of Applied mechanics1957,24,1:2
4Neonatal organ system injury in acute birth asphyxia sufficient to result in neonatal encephalopathy 显示文摘Hankins GD Koen S Gei AF 2003Obstetrics Gynecology2003,101,:1
5Chemistry of dissolved in organic carbon in estuarine and coastal brackish waters显示文摘Mook W G Koene B K S 1975Estuarine Coastal Marine Science1975,3,:1
6Estimates of disease effects on yields in the United States 2003 to 2005 显示文摘Wrather J A Koening S R 2006Journal of Nenmtology2006,38,:1
7Estimates of disease effects on soy- bean yields in the United States 2003 to 2005 显示文摘Wrather J A Koenning S R 2006Journal ofNematology2006,38,2:1
8A shapley decomposition of carbon emissionswithout residuals 显示文摘Johan A Delphine F Koen S 2002Energy Policy2002,30,:1
9Density-dependent yield of Heterodera glycinesre-sistant and susceptible ctfltivars显示文摘Koenning S R 2000Supplement to the Journal of Nematology2000,3,4:1
10Estimates of disease effects on soybean yields in the United States 2003 to 2005 显示文摘Wrather J A Koenning S R 2006Journal of Nematology2006,38,2:1
11A PCR-based method for identification of bifidobacteria from the human alimentary tract at the species level 显示文摘KOEN V ANNET J MAATHUI S 2003Fems Microbiology Letters2003,224,:1
12Neonatal organ system injury in acute birth asphyxia suffcient to result in neonatal encephalopathy显示文摘Hankins GD Koen S Gei AF 2002Obstet Gynecol2002,99,51:1
13Fast replanning for navigation in unknown terrain显示文摘Koening S Likhachev M 2005IEEE Transactions on Robotics2005,21,3:1
14A Shapley Decomposi- tion of Carbon Emissions Without Residuals显示文摘Johan A Delphine F Koen S 2002En- ergy Policy2002,30,:1
15A Dyadic Approach to the Impact of Differences in Organizational Culture on Relationship Performance 显示文摘Beugelsdijk S Koen C Noorderhaven N 2009Industrial Marketing Management2009,38,3:1
16Colloidal metal deposition onto functionalized polystyrene microspheres显示文摘Dokoutchaev A James J T Koene S C 1999Chem Mater1999,11,9:1
17Soybean dis-ease loss estimates for the United States from 1996 to1998显示文摘Wrather J A Stienstra W C Koenning S R 2001Can J Plant Pathol2001,23,2:1
18Anther developmental defects in Arabidopsis thaliana male - sterile mutants显示文摘Paul M S Anhthu Q B Koen W 1999Sex Plant Reprod1999,11,:1
19Dynamics of cryptogamic soil crusts in a derived grassland in southeastern Australia显示文摘Eldridge D J Semple W S Koen T B 2000Austral Ecology2000,25,3:1
20Soybean disease loss estimates for the United States from 1996 to 1998 显示文摘Wrather J A Stienstra W C Koenning S R 2001Canadian Journal of Plant Pathology2001,3,:1
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