维普中文期刊产品整合服务
22篇 您的检索式:作者名="Kitchener B A"
    题名 作者 年代 出处 被引量
1Proteolysis in milk: the significance of proteinases originating from milk leucocytes and a comparison of the action nf leucocute,bacterial and natural milk proteinases on casein显示文摘Grieve P A Kitchen B J 1985Journal of Dariy Research1985,52,:1
2Effects of mastiffs on milk yield, milk composition, processing properties and yield and quality of milk products Aust 显示文摘MUNRO E L GRIEVE P A KITCHEN B J 1984Dairy Technol1984,39,:1
3Fluorescent tren-based 4-amino-1,8-naphthalimide sensor for Cu (Ⅱ)based on the use of the (fluorophore-spacer-receptor)photoinduced electron transfer (PET) principle显示文摘Veale E B Kitchen J A Gunnlaugsson T 0,,2:1
4Acutemonoblastic leukemia of infancy in Klinefelter^ syn-drome显示文摘FOOT A B’OAKHILL A KITCHEN C 1992Cancer Genetic Cytogenet1992,61,:1
5Streptomycin and neo- mycin in veterinary medicine显示文摘Kitchen H B Waksman S A 1955American Veterina- ry Medical Association1955,127,942:1
6人乳头瘤病毒16/18型AS04佐剂疫苗预防肿瘤基因型HPV引起的宫颈感染和癌前病变的效应(PATRICIA):一项在年轻女性中进行的双盲、随机研究的最终分析显示文摘背景在年轻成人中进行的Ⅲ期随机、双盲对照PATRICIA试验(PApilloma TRial)的事件驱动期中分析显示,人乳头瘤病毒(HPV)16/18AS04佐剂疫苗具有免疫原性,且总体耐受性良好,对HPV16或HPV18感染及相关的癌前病变具有预防效应。本文作者旨在评估最终事件驱动分析中的疫苗效应。方法将在基线、1个月和6个月接种疫苗的15~25岁女性分类为符合方案的效应队列(ATP-E队列;疫苗组8093例,对照组8069例)、总接种队列(TVC;包括至少接种1剂疫苗的所有女性,而不考虑其基线HPV状态;代表普遍的年轻女性人群,包括性活跃者;疫苗组9319例,对照组9325例)和TVC-naive(无证据表明基线时存在肿瘤基因型HPV感染;代表无性行为女性;疫苗组5822例,对照组5819例)。主要终点是。在基线时血清和DNA均为阴性且在6个月时为相应类型(ATP-E队列)的女性中,评估疫苗对HPV16或HPV18相关性宫颈上皮内瘤变≥2级(CIN2+)的预防效应。该试验在ClinicalTrial.gov上的注册编码为NCT00122681.结果第3剂疫苗接种后平均随访34.9个月(s=6.4)。在主要分析中疫苗对HPV16/18相关性CIN2+的预防效应为92.9%(96.1%CI79.9%~98.3%),在对可能因多种肿瘤基因型HPV引起的病变(ATP-E队列)的分析中,其预防效应为98.1%(96.1%CI88.4%~100%)。不考虑病变HPVDNA时,疫苗对CIN2+的预防效应在TVC中为30.4%(96.1%CI16.4%~42.1%),在TVC-naive中为70.2%(96.1%CI54.7%~80.9%);而对CIN3+的相应效应在TVC中为33.4%(96.1%CI9.1%~51.5%).在TVC-naive中为87.0%(96.1%CI54.9%~97.7%).在预防12种非疫苗肿瘤基因型HPv相关性CIN2+的效应为54.0%(96.1%CI34.0%~68.4%:ATP-E队列)。在TVC中可见对HPV31、33和45相关性CIN2+的个体交叉保护效应。结论HPV16/18 AS04佐剂疫苗表现出对HPV16/18和非疫苗肿瘤基因型HPV相关性CIN2+较强的预防效应,而要获得整体预防效应就需要在更广泛的人群中进行大面积强化免疫计划。基金 葛兰素史克。J Paavonen P Naud J Salmeron C M Wheeler S-N Chow D Apter H Kitchener X Castellsague J C Teixeira S R Skinner J Hedrick U Jaisamrarn G Limson S Garland A Szarewski B Romanowski F Y Aoki T F Schwarz W A J Poppe F X Bosch D Jenkins K Hardt T Zahaf D Descamps F Struyf M Lehtinen G Dubin 周彩虹(译) 2009世界临床医学2009,,12:1
7Soybean root distribution related to claypan soil properties and apparent soil electrical conductiv- ity显示文摘Myers D B Kitchen N R Sudduth K A 2007Crop Science2007,47,4:1
8Peak functions for modeling high resolution soil profile data显示文摘Myers D B Kitchen N R Snddnth K A 2011C eoderma2011,16,1:1
9En-docytosis and interaction of poly(amidoamine) dendrimers withCaco-2 cells显示文摘KITCHENS K M FORAKER A B KOLHATKAR R B et at 2007Pharm Res2007,24,11:1
10Effects of mastitis on milk yield,milk composition,processing properties and yield and quality of milk products显示文摘Munro G L Grieve P A Kitchen B J 1984Aust J Dairy Technol1984,39,:1
11CD2 engagement induces dendritic cell activation: implications for immune surveillance and T cell activation 显示文摘Crawford K Stark A Kitchens B 2003Blood2003,102,17:1
12The Immune responseand fertility of koalas ( Phascolarctos cinereus) immunized withporcine zonae pellucidae or recombinant brushtail possum ZP3 protein显示文摘Kitchener A L Kay D J Walters B 2009J Reprod Immunol2009,82,1:1
13CD2 engagement induces dendritic cell activation:implications for immune surveillance and T-cell activation显示文摘CRAWFORD K STARK A KITCHENS B 2003Blood2003,102,5:1
14Effects of mastitis on milk yield,milk composition,processing properties and yield and quality of milk products显示文摘Munro G L Grieve P A Kitchen B J 1984Aust J Dairy Technol1984,39,:1
15Microscopic colitis: the tip of the iceberg?显示文摘Paul A Kitchen A Jonathen Levi Paula Domizio Ian C Talbot Alastair Forbes Ashley B Price 2002European Journal of Gastroenterology & Hepatology2002,,11:1
16Reviews of the progress of dairy science: the bovine milk fat globule membrane-its formation, composition, structure and behavior in milk and dairy products显示文摘MCPHERSON A V KITCHEN B J 1983J Dairy Res1983,50,:1
17E- valuation of pollutant build-up and wash-off from selected land uses at the Port of Brisbane,Australia显示文摘GOONETILLEKE A EGODAWATTA P KITCHEN B 2009Marine Pollution Bulletin2009,58,2:1
18CD2 engagement induces dendritic cell activation:implications for immune surveillance and T-cell activation显示文摘Crawford K Stark A Kitchens B 2003{H}Blood2003,,05:1
19Effects of mastitis on milk yield, milk composition, processing propertiesand yield and quality of milk products 显示文摘Munro G L Grieve P A Kitchen B J 1984Aust J Dairy Technol1984,39,:1
20Development of mental health first aid guidelines for panic attacks: A Delphi study显示文摘Kelly C M Jorm A F Kitchener B A 2009BMC Psychiatry2009,,9:1
返回顶部 每页显示:
共2页 首页 上一页 第1页 下一页 末页 /2 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费