|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | Numerical simulations of smoke movement from a pool fire in a ventilated tunnel显示文摘 | Flecher D F Kent J H Apte V B | 1994 | Fire SafJ1994，23，3： | 3 |
| 4 | Biomechanical Analysis of Distal Femur Fracture Fixation: Fixed-Angle Screw-Plate Construct Versus Condylar Blade Plate显示文摘 | Thomas F Higgins Gavin Pittman Jerod Hines Kent N Bachus | 2007 | Journal of Orthopaedic Trauma2007，，1： | 2 |
| 5 | Full-scale experimental investigation of repair of reinforced concrete interstate bridge using CFRP materials 显示文摘 | Aidoo John Harries Kent A Petrou Michael F | 2006 | Journal of Bridge Engineering2006，11，3： | 1 |
| 6 | Image analysis and fractal geometry to characterize soil desiccation cracks 显示文摘 | Baer J U Kent T F Anderson S H | 2009 | Geoderma2009，154，1： | 1 |
| 7 | Reexamining syphilis: an update on epidemiology, clinical manifestations, and management 显示文摘 | Kent ME Romanelli F | 2008 | Ann Pharmacother2008，42，2： | 1 |
| 8 | Metabolism of efavirenz and 8-hydroxyefavirenz by P450 2B6 leads to inactivation by two distinct mechanisms 显示文摘 | Bumpus N N Kent U M Hollenberg P F | 2006 | J Pharmacol Exp Ther2006，318，1： | 1 |
| 9 | An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD 显示文摘 | Syed Z Dudbridge F Kent L | 2007 | Am J Med Genet B Neuropsyehiatr Genet2007，144，3： | 1 |
| 10 | Effect of temperature on expression of genes encoding en- zymes for starch biosynthesis in developing wheat endosperm 显示文摘 | William J Hurkman Kent F McCue Susan B Ahenbach | 2003 | Plant Science2003，164，： | 1 |
| 11 | Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer:2010 update by the infectious diseases society of america显示文摘 | Alison G F Eric J B Kent A S | | 0，，04： | 1 |
| 12 | Anti - receptor for ad- vanced glycation end products therapies as novel treatment for abdomi- nal aortic aneurysm 显示文摘 | Zhang F Kent KC Yamanouchi D | 2009 | Ann Surg2009，250，3： | 1 |
| 13 | Image analysis and fractal geometry to characterize soil desiccation cracks显示文摘 | BAER J U KENT T F ANDERSON S H | 2009 | Geoderma2009，154，1： | 1 |
| 14 | STEP(satellite test of the equivalence principle)显示文摘 | Sumner T J Anderson J Blaser J P Cruise A M Damour T Dittus D Everitt C W F Fou-lon B Jafry Y Kent B J Lockerbie N Loeffler F Mann G Mester J Pegrum C ReinhardtR Sandford M Scheicher A Speake C C Torii R Theil S Touboul P Vitale S Vodel W Worden P W | 2007 | Advance in Space Re-search2007，39，2： | 1 |
| 15 | Induction of Shikimie Acid Pathway Enzymes by Light in Suspension Cultured Cells of Parsley ( Petroselinum erispum)显示文摘 | Kent F Meeue and Eric E Conn | 1990 | Plant Physiol1990，94，： | 1 |
| 16 | Reexamining syphilis : an update on epidemiology, clinical manifestations, and management 显示文摘 | Kent ME Romanelli F | 2008 | Ann Pharmacother2008，42，2： | 1 |
| 17 | Geochemical and isotopic constraints on the petrogenesis of the Noril' sk Talnakh ore-forming system 显示文摘 | Czamanske G K Wooden J L Zientek M L Fedorenko V A Zen' ko T E Kent J King B-S W Knight R J Siems D F | 1994 | Proceedings of the Sudbury Noril'' sk Symposium Ontario Geological Surrey Special Publication1994，5，： | 1 |
| 18 | Polarization dependence of response functions in 3 × 3 sagnac optical fiber currentsensors显示文摘 | Kent B R Gordon W D Peter R F | 1994 | Journal of Lightwarve Technology1994，12，8： | 1 |
| 19 | Increased incidengce ofdifferentiated thyroid carcinoma and detection of subclinical disease显示文摘 | Kent W D Hall S F Isotalo P A | 2007 | CMAJ2007，177，11： | 1 |
| 20 | BioMagResBank显示文摘 | Ulrich E L Akutsu H Doreleijers J F Harano Y Ioannidis Y E Lin J Livny M Mading S Maziuk D Miller Z Nakatani E Schulte C F Tolmie D E Kent Wenger R Yao H Markley J L | | 0，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员