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| 1 | 骨折相关性感染定义的共识显示文摘骨折相关性感染(fracture related infection,FRI)是创伤骨科一种常见的严重并发症.迄今为止,尚无明确定义,因此很难对该并发症带来的影响进行准确评估和对现有的研究展开比较.为解决这一难题,在AO基金会的支持下,我们成立了一个由科学家和医学专家组成的专家组,旨在对FRI定义达成的共识. | Metsemakers WJ Morgenstern M McNally MA Moriarty TF McFadyen I Scarborough M Athanasou NA Ochsner PE Kuehl R Raschke M Borens O 谢肇 Velkes S Hungerer S Kates SL Zalavras C Giannoudis PV Richard RG Verhofstad MH 喻胜鹏 孙东 汪小华 | 2018 | 中华骨科杂志2018，38，9： | 8 |
| 2 | Metabolic syndrome:A review of the role of vitamin D in mediating susceptibility and outcome显示文摘Despite the well-recognised role of vitamin D in a wide range of physiological processes,hypovitaminosis is common worldwide(prevalence 30%-50%) presumably arising from inadequate exposure to ultraviolet radiation and insufficient consumption.While generally not at the very low levels associated with rickets,hypovitaminosis D has been implicated in various very different,pathophysiological processes.These include putative effects on the pathogenesis of neoplastic change,inflammatory and demyelinating conditions,cardiovascular disease(CVD) and diabetes.This review focuses on the association between hypovitaminosis D and the metabolic syndrome as well as its component characteristics which are central obesity,glucose homeostasis,insulin resistance,hypertension and atherogenic dyslipidaemia.We also consider the effects of hypovitaminosis D on outcomes associated with the metabolic syndrome such as CVD,diabetes and non-alcoholic fatty liver disease.We structure this review into 3 distinct sections; the metabolic syndrome,vitamin D biochemistry and the putative association between hypovitaminosis D,the metabolic syndrome and cardiovascular risk. | Richard C Strange Kate E Shipman Sudarshan Ramachandran | 2015 | World Journal of Diabetes2015，6，7： | 5 |
| 3 | Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis显示文摘Importin 蛋白质原来通过原子毛孔在蛋白质运输为他们的中央角色被描绘,唯一的细胞内部的入口到原子核。这个重要函数必须紧被调整由抄写因素和另外的原子蛋白质控制存取到 genomic DNA,到完成细胞的行为影响的适当调整房间命运。调停 Importin 的 nucleocytoplasmic 运输依靠他们货物的特定的识别,与到不同、重叠的蛋白质子集的每 importin 绑定。importin 功能的知识关于三个关键发展系统实质地膨胀了:胚胎的干细胞,肌肉房间和细菌排队。自从为调整 nucleocytoplasmic 运输的潜力被建议贡献精子发生,在十年,我们和其它证明了进原子核的渡船抄写因素执行的 importins 另外的角色,它控制房间命运。这评论从哺乳动物的精子发生的研究介绍关键调查结果揭示男富饶和不孕由产生的潜在的新小径。germline 开始的这些研究照亮 importin 蛋白质在管理细胞的区别的新方法,经由指导到不同细胞内部的分隔空间并且由决定细胞的压力回答的蛋白质包括。 | Kate L Loveland Andrew T Major Romaly Butler Julia C Young David A Jan Yoichi Miyamoto | 2015 | Asian Journal of Andrology2015，17，4： | 3 |
| 4 | Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals显示文摘发炎是对试图消除侮辱的微生物引起的感染或无菌的损害的主人反应,修理织物并且恢复动态平衡。巨噬细胞和 NLRP3 inflammasome 是为侮辱的两种类型的关键哨兵。尽管 NLRP3 inflammasome 被在无菌的损害期间释放的微生物引起的产品和分子激活,这很好被建立,信号的这些不同类型得到的回答是否是不同的,是不清楚的。在这研究,我们把 lipopolysaccharide 和肿瘤坏死因素用作原型的微生物引起、无菌的信号 1 刺激,分别地告知 NLRP3 inflammasome。我们然后使用了细菌的毒素 nigericin 和免除坏死的房间的一个普通产品, ATP 原型的微生物引起、无菌的信号 2 刺激,分别地在鼠标和人的巨噬细胞触发 NLRP3 inflammasome 建筑群的汇编。当信号 1 和信号 2 是无菌的时,我们发现 NLRP3 inflammasome 回答最弱,但是当二个信号中的至少一个是微生物引起的时,回答更快、更强壮。最终,最快速并且当两个信号是微生物引起的时,有势力回答被得到。一起,这些数据建议微生物引起对无菌的信号是不同的,运动地并且在大小,处于他们产生 inflammasome 依赖的回答的能力。对无菌对微生物引起的刺激的 NLRP3 回答的这个层次多半反映迫切需要让免疫系统对感染的存在很快作出回应停止病原体传播。 | Jelena S Bezbradica Rebecca C Coll Kate Schroder | 2017 | Cellular & Molecular Immunology2017，14，1： | 3 |
| 5 | Environment and Development: Sustainability Science 显示文摘 | Kates R W Clark W C Corell R | 2001 | Science2001，，292： | 1 |
| 6 | Metadata for digital collections: A how-to-do-it manual显示文摘 | Kate C | 2011 | Records Management Journal2011，30，2： | 1 |
| 7 | Environment and Development: Sustainability Science显示文摘 | Kates R W Clark W C Corell R | 2001 | Science2001，292，： | 1 |
| 8 | Environ- ment and Development: Sustainability Science 显示文摘 | Kates R W Clark W C Corell R | 2001 | Science2001，292，5517： | 1 |
| 9 | ICARFAD:a novel framework for improved network security situation awareness 显示文摘 | Sharma C Kate V | 2014 | International Journal of Computer Applications2014，87，19： | 1 |
| 10 | Environment anddevelopment:sustainability science显示文摘 | Kates R W Clark W C Corell R | 2001 | Science2001，292，： | 1 |
| 11 | Venous thromboembolic pro- phylaxis for hip fractures显示文摘 | Marsland D Mears S C Kates S L | 2010 | Osteoporosis International2010，21，4： | 1 |
| 12 | Sleep and sleep disorders in older adults 显示文摘 | Kate C | 2011 | Neuropsychology review2011，21，： | 1 |
| 13 | Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial显示文摘 | Dileep N Lobo Kate A Bostock Keith R Neal Alan C Perkins Brain J Rowlands Simon P Allison | 2002 | The Lancet . 2002 (9320)2002，，9320： | 1 |
| 14 | ICARFAD: A novel frame- work for improved network security situation aware- ness显示文摘 | SHARMA C KATE V | 2014 | International Journal of Computer Applica- tions2014，87，19： | 1 |
| 15 | Linkage and mutational analysis of CLCN2 in childhood absence epilepsy 显示文摘 | Kate E Barry C Jean A | 2007 | Epilepsy Research2007，75，23： | 1 |
| 16 | Maize HapMap2 identifies extant variation from a genome in flux 显示文摘 | Jer-Ming Chia Chi Song Peter J Bradbury Denise Cos- tich Natalia de Leon John Doebley Robert J Elshire Brandon Gaut Laura Geller Jeffrey C Glaubitz Michael Gore Kate E Guill Jim Holland Matthew B Hufford Jinsheng Lai Meng Li Xin Liu Yanli Lu Richard Mc- Combie Rebecca Nelson Jesse Poland Boddupalli M Prasanna Tanja Pyhajarvi Tingzhao Rong Rajandeep S Sekhon Qi Sun Maud I Tenaillon Feng Tian Jun Wang Xun Xu Zhiwu Zhang Shawn M Kaeppler Jef- frey Ross-lbarra Michael D McMullen Edward S Buck- ler Gengyun Zhang Yunbi Xu Doreen Ware | 2012 | Nat Genet2012，，44： | 1 |
| 17 | Evaluation of transient elastography for fibrosis assessment compared with large biopsies in chronic hepatitis B and C 显示文摘 | VERVEER C ZONDERVAN P E TEN KATE F J W | 2012 | Liver Int2012，32，4： | 1 |
| 18 | Environment and development:Sustainability science显示文摘 | KATES R W CLARK W C CORELL R | 2001 | Science2001，292，5517： | 1 |
| 19 | Brand morphing-implications for advertising theory and practice显示文摘 | Kates S M Goh C | 2003 | Joumal of Advertising2003，32，1： | 1 |
| 20 | Environment and development:sustainability science显示文摘 | Kates R W Clark W C Corell R | 2001 | Science2001，292，： | 1 |
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