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| 1 | Regulation and tissue distribution of the human sodium iodide symporter gene 显示文摘 | Ajjan RA Kamaruddin NA Crispt M | 1998 | Clin Endrocrinol1998，49，： | 1 |
| 2 | Insulin resistance using HOMA model in obstructive sleep apnea:a cross sectional study 显示文摘 | Azman M Sani A Kamaruddin NA | 2014 | Ann Saudi Med2014，34，47： | 1 |
| 3 | Regulation and tissue distribution of the human sodium iodide symporter gene 显示文摘 | Ajjan RA Kamaruddin NA Crisp M | 1998 | Clin Endocrinol Oxf1998，49，： | 1 |
| 4 | A low-GI diet isassociated with ashort term improvement of glycaemic controlin Asian patients with type 2 diabetes显示文摘 | Yusof BN Talib RA Kamaruddin NA | 2009 | Diabetes ObesMetab2009，11，： | 1 |
| 5 | Regulation and tissue distribution of the human sodium iodide symporter gene显示文摘 | Ajjan RA Kamaruddin NA Crisp M | 1998 | Clin Endocrinol Oxf1998，49，： | 1 |
| 6 | Regulation and tissue distribution of the human sodium iodide symporter gene 显示文摘 | Ajjan RA Kamaruddin NA Crisp M | 1998 | Cline endorine Oxf1998，49，4： | 1 |
| 7 | Regulation and tissue distribution of the human sodium iodide symporter gene显示文摘 | Ajjan RA Kamaruddin NA Crisp M | 1998 | Clin Endocrinol1998，49，4： | 1 |
| 8 | A low-GI diet is associated with a short-term improvement of glycaemic control in Asian patients with type 2 diabetes 显示文摘 | Yusof BN Talib RA Kamaruddin NA | 2009 | Diabetes Obes Metab2009，11，38： | 1 |
| 9 | Regulation and tissue distribution of the human sodium/iodide symporter gene显示文摘 | Ajjan RA Kamaruddin NA Cirsp M | 1998 | Clin Endocrino1998，49，： | 1 |
| 10 | A low-GI diet isassociated with a short-tern improvement of glycaemic control in Asian patients with type 2 diabetes显示文摘 | Yusof BN Talib RA Kamaruddin NA | 2009 | Diabetes Obes Metab2009，11，： | 1 |
| 11 | A low GI diet is associated with a short term improvement of glycaemic control in Asian patients with type 2 diabetes 显示文摘 | Yusof BN Talib RA Kamaruddin NA | 2009 | Diabetes Obes Metab2009，11，2： | 1 |
| 12 | Comparison of Cox proportional hazards model,Cox proportional hazards with time-varying coefficients model,and lognormal accelerated failure time model:Application in time to event analysis of melioidosis patients显示文摘Objective:To compare the prognostic factors of mortality among melioidosis patients between lognormal accelerated failure time(AFT),Cox proportional hazards(PH),and Cox PH with time-varying coefficient(TVC)models.Methods:A retrospective study was conducted from 2014 to 2019 among 453 patients who were admitted to Hospital Sultanah Bahiyah,Kedah and Hospital Tuanku Fauziah,Perlis in Northern Malaysia due to confirmed-cultured melioidosis.The prognostic factors of mortality from melioidosis were obtained from AFT survival analysis,and Cox’s models and the findings were compared by using the goodness of fit methods.The analyses were done by using Stata SE version 14.0.Results:A total of 242 patients(53.4%)survived.In this study,the median survival time of melioidosis patients was 30.0 days(95%CI 0.0-60.9).Six significant prognostic factors were identified in the Cox PH model and Cox PH-TVC model.In AFT survival analysis,a total of seven significant prognostic factors were identified.The results were found to be only a slight difference between the identified prognostic factors among the models.AFT survival showed better results compared to Cox's models,with the lowest Akaike information criteria and best fitted Cox-snell residuals.Conclusions:AFT survival analysis provides more reliable results and can be used as an alternative statistical analysis for determining the prognostic factors of mortality in melioidosis patients in certain situations. | Kamaruddin Mardhiah Nadiah Wan-Arfah Nyi Nyi Naing Muhammad Radzi Abu Hassan Huan-Keat Chan | 2022 | Asian Pacific Journal of Tropical Medicine2022，15，3： | 0 |
| 13 | Reversal of multidrug resistance and antitumor promoting activity of 3-oxo-6β-hydroxy-β-amyrin isolated from Pistacia integerrima显示文摘The bioactive triterpenoid 3-oxo-6-β-hydroxy-β-amyrin(1)has been isolated from multiple plant sources.In this study,chloroform fraction of Pistacia integerrima extract was processed for the isolation of the compound.The compound identity was confirmed by advanced spectroscopy technique.X-ray crystallography was applied for molecular structure confirmation.In addition,compound 1 was screen for its activity on reversal of MDR(multidrug resistance)mediated by P-gp(P-glycoprotein).This was accomplished by using rhodamine123 exclusion on multidrug-resistant human ABCB1 gene transfected mouse T-lymphoma cell line.Outcomes revealed that MDR reversing effect was comparable to verapamil as positive control in vitro.Treatment of TPA-induced tumor promotion with 3-oxo-6β-hydroxy-β-amyrin led to reduction in the applied anti-tumor promotion experiment.The chemo-preventive effect of 3-oxo-6β-hydroxy-β-amyrin was comparable to curcumin as positive control based on the reduction of immediate early tumor antigen expression.Molecular docking by applying Autodock Vina 1 and i-GEMDOCK v 2.1 tools indicated that compound 1 gives good docking results,as determined by their fitness score and specificity.Moreover,results showed that compound 1 isolated from Pistacia integerrima precisely attached to a region where co-crystallized ligand for receptor previously existed.Our findings may explain the use of Pistacia integerrima plant extracts as an anticancer agent in folk medicine. | ABDUR RAUF SAUD BAWAZEER MUSLIM RAZA EMAN EL-SHARKAWY MD.HABIBUR RAHMAN MOHAMED A.EL-ESAWI GHIAS UDDIN BINA SSIDDIQUI ANEES AHMED KHALIL JOSEPH MOLNAR AKOS CSONKA DIÁNA SZABÓ HAROON KHAN MOHAMMAD SMUBARAK TAIBI BEN HADDA MUDYAWATI KAMARUDDIN SEEMA PATEL | 2021 | BIOCELL2021，45，1： | 0 |
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