|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Biliary complications following liver transplantation: Singlecenter experience over three decades and recent risk factors显示文摘AIM To identify independent risk factors for biliary complications in a center with three decades of experience in liver transplantation.METHODS A total of 1607 consecutive liver transplantations were analyzed in a retrospective study. Detailed subset analysis was performed in 417 patients, which have been transplanted since the introduction of Model of End-Stage Liver Disease(MELD)-based liver allocation. Risk factors for the onset of anastomotic biliary complications were identified with multivariable binary logisticregression analyses. The identified risk factors in regression analyses were compiled into a prognostic model. The applicability was evaluated with receiver operating characteristic curve analyses. Furthermore, Kaplan-Meier analyses with the log rank test were applied where appropriate. RESULTS Biliary complications were observed in 227 cases(14.1%). Four hundred and seventeen(26%) transplantations were performed after the introduction of MELD-based donor organ allocation. Since then, 21%(n = 89) of the patients suffered from biliary complications, which are further categorized into anastomotic bile leaks [46%(n = 41)], anastomotic strictures [25%(n = 22)], cholangitis [8%(n = 7)] and non-anastomotic strictures [3%(n = 3)]. The remaining 18%(n = 16) were not further classified. After adjustment for all univariably significant variables, the recipient MELD-score at transplantation(P = 0.006; OR = 1.035; 95%CI: 1.010-1.060), the development of hepatic artery thrombosis post-operatively(P = 0.019; OR = 3.543; 95%CI: 1.233-10.178), as well as the donor creatinine prior to explantation(P = 0.010; OR = 1.003; 95%CI: 1.001-1.006) were revealed as independent risk factors for biliary complications. The compilation of these identified risk factors into a prognostic model was shown to have good prognostic abilities in the investigated cohort with an area under the receiver operating curve of 0.702.CONCLUSION The parallel occurrence of high recipient MELD and impaired donor kidney function should be avoided. Risk is especially increased when post-transplant hepatic artery thrombosis occurs. | Alexander Kaltenborn André Gutcke Jill Gwiasda Jürgen Klempnauer Harald Schrem | 2017 | World Journal of Hepatology2017，9，3： | 6 |
| 2 | Decision modelling for economic evaluation of liver transplantation显示文摘As the gap between a shortage of organs and the immense demand for liver grafts persists, every available donor liver needs to be optimized for utility, urgency and equity. To overcome this challenge, decision modelling might allow us to gather evidence from previous studies as well as compare the costs and consequences of alternative options. For public health policy and clinical intervention assessment, it is a potentially powerful tool. The most commonly used types of decision analytical models include decision trees, the Markov model, microsimulation, discrete event simulation and the system dynamic model. Analytic models could support decision makers in the field of liver transplantation when facing specific problems by synthesizing evidence, comprising all relevant options, generalizing results to other contexts, extending the time horizon and exploring the uncertainty. For modeling studies of economic evaluation for transplantation, understanding the current nature of the disease is crucial, as well as the selection of appropriate modelling techniques. The quality and availability of data is another key element for the selection and development of decision analytical models. In addition, good practice guidelines should be complied, which is important for standardization and comparability between economic outputs. | Zhi Qu Christian Krauth Volker Eric Amelung Alexander Kaltenborn Jill Gwiasda Lena Harries Jan Beneke Harald Schrem Sebastian Liersch | 2018 | World Journal of Hepatology2018，10，11： | 6 |
| 3 | Flexible Intermediate Bulk Container (FIBC) under Dynamic Load显示文摘 | LANGEFELD O KALTENBORN S | 2006 | Powder Handling and Processing2006，18，： | 1 |
| 4 | Expiratory computed tomography for assessment of suspected pulmonary emphysema 显示文摘 | Knudson RJ Standen JR Kaltenborn WT | 1991 | Chest1991，99，： | 1 |
| 5 | The meaning of place: attachments to Femundsmarka National Park, Norway, among tourists and locals显示文摘 | Bj?rn P. Kaltenborn Daniel R. Williams | 2002 | Norsk Geografisk Tidsskrift - Norwegian Journal of Geography2002，，3： | 1 |
| 6 | Setting preferences of Arctic tourists: a study of some assumptions in the recreation opportunity spectrum framework from the Svalbard Archipelago显示文摘 | B. P. Kaltenborn | 1999 | Norsk Geografisk Tidsskrift - Norwegian Journal of Geography1999，，1： | 1 |
| 7 | Expiratory computed tomography for assessment of suspected pulmonary emphysema显示文摘 | Knudson RJ Standen JR Kaltenborn WT | 1991 | Chest1991，99，6： | 1 |
| 8 | Consumptive orientation of anglers in Engerdal,Norway显示文摘 | KALTENBORN B P | 1995 | Environmental Management1995，19，5： | 1 |
| 9 | The meaning of place:attachments to Femundsmarka National Park,Norway,among tourists and locals显示文摘 | Kaltenborn B P Williams D R | | 0，，03： | 1 |
| 10 | The meaning of place: Attaehment to Femundsmarka National Park, Norway, a- mong tourists and locals显示文摘 | Kaltenborn B P Williams D R | 2002 | Norwegian Journal of Geog- raphy2002，56，3： | 1 |
| 11 | Flexible Intermediate Bulk Container(FIBC)Under Dynamic Load显示文摘 | Langefeld O Kaltenborn S | 2006 | Powder Handling and Processing2006，18，： | 1 |
| 12 | Respiratory syncytial virus potentiates ABCA3 mutation-induced loss of lung epithelial cell differentiation 显示文摘 | Kaltenborn E Kern S Frixel S | 2012 | Hum Mol Gente2012，21，12： | 1 |
| 13 | Associations between environmental value orientations and landscape preferences显示文摘 | Kaltenborn B P Bjerke T(2002a) | 2002 | Landscape and Urban Planning2002，111，： | 1 |
| 14 | Virtual reality in medicine 显示文摘 | Kaltenborn KF Rienhoff O | 1993 | Methods Inf Med1993，32，5： | 1 |
| 15 | Respiratory syncytial virus potentiates ABCA3 mutation-induced loss of lung epithelial cell differentiation 显示文摘 | Kaltenborn E Kern S Frixel S | 2012 | Hum Mol Genet2012，21，12： | 1 |
| 16 | Associations between environmental value orientations and landscape preferences显示文摘 | Kaltenborn B P Bjerke T | 2002 | Landscape and Urban Planning2002，59，： | 1 |
| 17 | Bioactivation of inert alumina ceramics by hydroxylation 显示文摘 | Fischer H Niedhartb C Kaltenborn N | 2005 | Biomaterials2005，26，： | 1 |
| 18 | Factors influencing conservation attitudes of local people in Western Serengeti, Tanzania 显示文摘 | Kideghesho J R R skaft E Kaltenborn B P K | 2007 | Biodivers Conserv2007，16，： | 1 |
| 19 | Local governance of national parks:The perception of tourism operators in Dovre-Sunndalsfjella National Park,Norway显示文摘 | Kaltenborn B P Qvenild M Nellemann C | | 0，，65： | 1 |
| 20 | Nature of Place Attachment: A Study Among Recreation Homeowners in Southern Norway显示文摘 | B P Kaltenborn | 1997 | Leisure Sciences1997，19，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员