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| 1 | Absence seizures aggravated by valproie acid 显示文摘 | Lerman Sagie T Watemberg N Kramer U Shahar E Mermen P | 2001 | Epilepsia2001，42，7： | 1 |
| 2 | 早期将抗生素由静脉转为口服治疗严重社区获得性肺炎:多中心随机试验显示文摘目的比较早期由静脉转换成口服抗生素与常规静脉使用7天抗生素治疗严重社区获得性肺炎(CAP)的疗效。设计多中心随机对照试验。地点荷兰5家教学医院和2所大学的医学中心。参加者非 ICU 住院的严重 CAP 患者302例,其中265例满足研究要求。干预静脉抗生素治疗3天,病情稳定后换成口服抗生素,或静脉使用抗生素治疗7天。主要评价结果临床治愈和住院天数。结果 302例患者被随机分组(平均年龄69.5岁,标准差14.0),肺炎严重度评分平均112.7(26.0)。37例患者因为提前3天退出而未纳入分析,对其余265例患者进行分析研究。第28天的死亡率在干预组是4%,对照组是6%(平均差2%,95%可信区间-3%~8%)。临床治愈率在干预组是83%,对照组是85%(2%;-7%~10%)。与对照组相比,干预组患者静脉治疗时间为3.4天[3.6(1.5)比7.0(2.0)天;2.8~3.9],患者住院天数减少1.9天[9.6(5.0)比11.5(4.9)天;0.6~3.2]。结论早期将抗生素由静脉应用转换成口服治疗严重 CAP 是安全的,并且可以减少住院时间2天。试验注册号临床试验 NCT00273676。 | Jan Jelrik Oosterheert Marc J M Bonten Margriet M E Schneider Erik Buskens Jan-Willem J Lammers Willem M N Hustinx Mark H H Kramer Jan M Prins Peter H Th J Slee Karin Kaasjager Andy I M Hoepelman 王伟巍(译) 童朝辉(校) | 2007 | 英国医学杂志中文版2007，10，2： | 1 |
| 3 | Biochemical effects on contaminant fate and transport 显示文摘 | Nyer E K Kramer V Valkenburg N | 1991 | Groundwater Monitoring & Remediation1991，11，2： | 1 |
| 4 | A novel role of the hedgehog pathway in lens regeneration显示文摘 | Tsonis P A Vergara M N Spence J R Madhavan M Kramer E L Call M K | 2004 | Dev Biol2004，267，： | 1 |
| 5 | Influence of task-irrelevant onset distractors on visual search显示文摘 | Cassavaugh N D Kramer A F Irwin D E | | 0，，10： | 1 |
| 6 | Chemical modifiers of cancer treatment显示文摘 | COLEMAN N BUMP E KRAMER R | | 0，，04： | 1 |
| 7 | Do preschools differ in promoting children's physical activity?An instrument for the assessment of preschool physical activity programmes显示文摘 | Sterdt E Pape N Kramer S Urban M Werning R Walter U | 2013 | BMC public health2013，13，： | 1 |
| 8 | The preparation, testing and certification of two freshwater sediment reference materials for polycyclic aromatic hydrocarbons and polychlorinated biphenyls: BCR CRM 535 and CRM 536 显示文摘 | Wegener J W M Cofino W P Maier E A Kramer G N | 1999 | Trends in Analytical Chemistry1999，18，1： | 1 |
| 9 | Salmonella enterica serovar Typhi possesses a unique repertoire of fimbrial gene sequences 显示文摘 | Townsend S M Kramer N E Edwards R | 2001 | Infect Immun2001，69，5： | 1 |
| 10 | Substrate effects on indentation plastic zone development in thin soft films 显示文摘 | Kramer D E Volinsky A A Moody N R Gerberich W G | 2001 | J Mater Res2001，16，11： | 1 |
| 11 | Feeding wheat dried dis tillers grains with solubles improves beef trans and conjugated lin oleicacidprofiles显示文摘 | Dugan M E Aldai N Kramer J K | 2010 | JournalAnimSci2010，88，5： | 1 |
| 12 | Assessment of recent process analytical technology (PAT) trends: a multiauthor review显示文摘 | Simon L L Pataki H Marosi G Meemken F Hungerbiihler K Baiker A Tummala S Glennon B Kuentz M Steele G Kramer H J M Rydzak J W Chen Z Morris J Kjell F Singh R Gani R Gernaey K V Louhi-Kultanen M O'Reilly J Sandler N Antikainen 0 Yliruusi J Frohberg P Ulrich J Braatz R D Leyssens T von Stosch M Oliveira R Tan R B H Wu H Khan M O'Grady D Pandey A Westra R Delle-Case E Pape D Angelosante D Maret Y Steiger 0 Lenner M Abbou-Oucherif'K Nagy Z K Litster J D Kamaraju V K Chiu M-S | 2015 | Organic Process Research & Development2015，19，1： | 1 |
| 13 | Forward Recoil Spectrometry Study of the Diffusion of PMDA/ODA-based Poly( amic ethyl esters) 显示文摘 | Stoffel N C Chandra S Kramer E J | 1997 | Polymer1997，38，20： | 1 |
| 14 | 查看详情显示文摘 | Dils B De Maziere M Muller J F Blumenstock T Buchwitz M de Beek R Demoulin P Duchatelet P Fast H Frankenberg C Gloude- mans A Griffith D Jones N Kerzenmacher T Kramer I Mahieu E Mellqvist J Mittermeier R L Notholt J Rinsland C P Schrijver | | 0，，： | 1 |
| 15 | Mechanism of electrochromism in WO3 显示文摘 | Hersh H N Kramer W E McGee J H | 1975 | Applied Physics Letters1975，27，12： | 1 |
| 16 | Nanoindentation-induced defect-interface interactions: Phenomena, methods and limitations 显示文摘 | GERBERICH W W KRAMER D E TYMIAK N I | 1999 | Acta Materialia1999，47，15： | 1 |
| 17 | In-creased D-alanylation of lipoteichoic acid and a thickened septum aremain determinants in the Nisin resistance mechanism of Lactococcus lac-tis显示文摘 | KRAMER N E HASPER H E VAN DEN BOGAARD P T C | 2008 | Microbiol2008，154，6： | 1 |
| 18 | Dimensionality and directionality effects in Newmark Sliding Block Analyses显示文摘 | Kramer S E Lindwall N W | 2004 | Journal of Geotechnical and Geoenvir onmental Engineering2004，130，3： | 1 |
| 19 | Transcriptome analysis reveals mechanisms by which Lactococcus lactis acquires nisin resistance显示文摘 | Kramer N E Van Hijum S A Knol J | 2006 | Antimicrob Agents Chemother2006，50，5： | 1 |
| 20 | Gemcitabine and cisplatin as induction regimen for patients with biopsy proven stage IIIA N2 non small cell lung cancer:a phase Ⅱ study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group(EORTC 08955)显示文摘 | VAN ZANDWIJK N SMIT E F KRAMER G W | 2000 | J Clin Oncol2000，18，14： | 1 |
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