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| 1 | Expression of inducible nitric oxide synthase and cyclooxygenase-2 in pancreatic adenocarcinoma:Correlation with microvessel density显示文摘AIM: Cydooxygenases (COX) are key enzymes for conversion of arachidonic acid to prostaglandins. Nitric oxide synthase (NOS) is the enzyme responsible for formation of nitric oxide.Both have constitutive and inducible isoforms. The inducible isoforms (iNOS and COX-2) are of great interest as regulators of tumor angiogenesis, tumorigenesis and inflammatory processes. This study was to clarify their role in pancreatic adenocarcinomas.METHODS: We investigated the immunohistochemical iNOS and COX-2 expression in 40 pancreatic ductal adenocarcinomas of different grade and stage. The results were compared with microvessel density and clinicopathological data.RESULTS: Twenty-one (52.5%) of the cases showed iNOS expression, 15 (37.5%) of the cases were positive for COX-2.The immunoreaction was heterogeneously distributed within the tumors. Staining intensity was different between the tumors. No correlation between iNOS and COX-2 expression was seen. There was no relationship with microvessel density.However, iNOS positive tumors developed more often distant metastases and the more malignant tumors showed a higher COX-2 expression. There was no correlation with other clinicopathological data.CONCLUSION: Approximately half of the cases expressed iNOS and COX-2. These two enzymes do not seem to be the key step in angiogenesis or carcinogenesis of pancreatic adenocarcinomas. Due to a low prevalence of COX-2 expression, chemoprevention of pancreatic carcinomas by COX-2 inhibitors can only achieve a limited success. | Hans U.Kasper Hella Wolf Uta Drebber Helmut K.Wolf Michael A.Kern | 2004 | World Journal of Gastroenterology2004，10，13： | 14 |
| 2 | 印刷工业的网络传播显示文摘通过PC机和数字式照相机使文字和图像数字化,就可通过数字数据线路传输文字、图像,井制作印版。用户、广告代理、印前制作中心和印刷厂都可通过ISDN网以数字式方式传送订单。从IMPRINTA97展览会及印刷与媒体讨论会,人们可以了解到这项技术是如何应用的。IMPRINTA97展示了各种软片及印版照排机用数字打样及数字印刷过程所用的远程数据传输系统,显然,通过联网通讯,在很大程度上改善了客户间的联系。 直到几年以前。 | Kurt K.Wolf 葛冰 | 1997 | 今日印刷1997，，5： | 0 |
| 3 | 从黑白数码印刷到彩色喷墨印刷显示文摘据《德国印刷者》资深的编辑Kurt K.Wolf近期在杂志上撰文报道,奥西(Oce)印刷系统公司推出用于直邮和交易印刷(Transactionsprint)的新产品。该公司以新型彩色喷墨印刷系统踏上了全彩色印刷的发展之路。 | Kurt K.Wolf 徐世垣 | 2009 | 数码印刷2009，，7： | 0 |
| 4 | 无低聚物问题的聚酯织物染色显示文摘聚酯织物的浅色和中色色调染色工艺中使用德国司马化学公司开发的新型低聚物分散剂Zetesan Ole,就完全没必要进行碱后处理工艺。如果实施了预试验,则Zetesan Ole和纱线润滑剂可用于一浴法染色工艺中。 | G.Gebhardt F.Richter A.Schnfeld K.Wolf 王文义 | 2010 | 国际纺织导报2010，，12： | 0 |
| 5 | 印刷业正在健康发展显示文摘印刷业从未像今天这样健康地发展,将于2004年5月6~19日在德国召开的Drupa 2004将是'彩色印刷的Drupa',是聚焦传统胶印、凹印和柔印工艺的彩色印刷和自动化发展的Drupa,是展示数码印刷中彩色激光和喷墨印刷技术以及各种各样印刷应用的Drupa。它将令每一位Drupa 04的参观者亲身体验各种印刷生产方法和创新产品带来的震撼。 | Kurt K.Wolf 陈虹(编译) | 2003 | 数码印刷2003，，10： | 0 |
| 6 | CTP对胶片和印版生产的冲击显示文摘无论是照排系统直接对胶片曝光,还是对印版直接曝光(计算机直接制版),对整张印版进行曝光已经成为印前技术的发展趋势.这个趋势对胶片或印版消费有哪些影响呢?针对这个问题,在距Ipex 2002开幕不到一年的关头,Kurt K. Wolf对胶片和印版生产商以及他们的产品进行了调查研究. | Kurt K.Wolf 初名梅 | 2001 | 印刷技术2001，，25： | 0 |
| 7 | Improved thromboresistance and analytical performance of intravascular amperometric glucose sensors using optimized nitric oxide release coatings显示文摘In this work,nitric oxide(NO) release coatings designed for intravenous amperometric glucose sensors are optimized through the use of a polylactic acid(PLA) layer doped with a lipophilic diazeniumdiolated species that releases NO through a proton-driven mechanism.An Elast-Eon E2 As polyurethane coating is used to both moderate NO release from the sensor surface and increase the sensor's linear detection range toward glucose.These sensors were evaluated for thromboresistance and in vivo glucose performance through implantation in rabbit veins.By maintaining NO flux on a similar scale to endogenous endothelial cells,implanted glucose sensors exhibited reduced surface clot formation which enables more accurate quantitative glucose measurements continuously.An in vivo time trace of implanted venous sensors demonstrated glucose values that correlated well with the discrete measurements of blood samples on a benchtop point-of-care sensor-based instrument.The raw measured currents from the implanted glucose sensors over 7 h time periods were converted to glucose concentration through use of both a one-point in vivo calibration and a calibration curve obtained in vitro within a bovine serum solution.Control sensors,assembled without NO release functionality,exhibit distinctive surface clotting over the 7 h in vivo implantation period. | Alexander K.Wolf Yu Qin Terry C.Major Mark E.Meyerhoff | 2015 | Chinese Chemical Letters2015，26，4： | 0 |
| 8 | 弹力织物经济和环境友好的整理新途径—Depicol RC 9显示文摘在对含弹性纤维的纺织品整理时 ,要特别重视对织物的前处理。主要是去除纤维纺丝油剂 ,尤其是弹性纤维表面的有机硅润滑剂。本文从经济和环保角度介绍了聚酰胺 | N.Wickert A.Schnfeld S.Mubius C.Schffler K.Wolf 吕晶 | 2002 | 国际纺织导报2002，30，4： | 0 |
| 9 | 白色及染色PA/EL织物后整理中的泛黄问题显示文摘描述了两种用于聚酰胺和聚酰胺/弹性纤维混纺织物的创新工艺——Econ-BrightLG和EconDyeLG,这两种新工艺提供了经济的及质量可靠的工艺控制。通过应用DepicolAY和DepicolLG泛黄问题可减小至最少限度。这两种纺织品助剂用于-浴洗涤/染色和后整理工艺中,是Zschimmer&Schwarz公司开发的。 | C.Hemeltjen A.Mehlhorn S.Mbius K.Wolf A.Schnfeld 吴芳群 | 2005 | 国际纺织导报2005，33，3： | 0 |
| 10 | 工艺流程管理——印前阶段的自动化显示文摘印前阶段的工序,从页面生成到印版,是由许多独立的工作阶段来组成的。由于有了数字化,现在通过计算机就可自动将各个工序排列起来,无需操作人员辅助。工艺流程管理成为印前公司自动化的最重要的部分。 | Kurt K.Wolf 高晶 | 1998 | 今日印刷1998，，5： | 0 |
| 11 | CTP使胶印更具吸引力显示文摘在drupa2008展览会上,数码印刷机像胶印机一样.受到参观者的高度重视。数码印刷机在短版印刷上将会比胶印更快.更具竞争力:胶印机则会幅面更大.更换活件更快.自动化程度更高。当数码印刷机在短版印刷中增长时.胶印则在各种规模的胶印厂的大批量生产的印刷市场中得到发展。 | Kurt K.Wolf | 2008 | 数码印刷2008，，6： | 0 |
| 12 | 氧化锆(Zirkonoxid)化学工业中一种制造泵的新材料显示文摘重要的计划和设计的实现往往需要解决不同的材料问题和一个或几个构件问题。本文谈及的现代化的陶瓷材料为设计人员实现他的理想提供了一条新的途径。现在如果没有陶瓷就不会有许多产品或者生产出的产品会有很高的修理率或需更换机器。陶瓷组件的应用正在稳固地增长,证实了陶瓷材料最突出的特性即显著提高了寿命,体现了最终产品的价值。本文叙述了锆(ZrO_2)材料在化学工业和在制造泵方面的展望。 | K.Wolf Th.Holzhueter 汪慧琴 | 1989 | 氮肥设计1989，，3： | 0 |
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