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4篇 您的检索式:作者名="K.Kulkarni"
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1腋窝淋巴结疑为乳腺癌转移:超声引导下14G芯针穿刺活检采样100例的临床经验显示文摘目的 研究超声引导下腋窝淋巴结芯针活检的临床应用,以及可预测淋巴结转移的异常超声征象。方法 该回顾性研究符合HIPAA法案,获审查委员会批准,无需病人知情同意。144例经过腋窝淋巴结超声评估的原发性乳腺癌病人中的100例接受了超声引导下腋窝淋巴结的14G芯针活组织检查。活检针是可控的,而不是传统使用的投掷型(throw-type)针。H.Abe R.A.Schmidt K.Kulkarni C.A.Sennett J.S.Mueller G.M.Newstead 朱玉兆 2009国际医学放射学杂志2009,32,2:23
2Microsponge based drug delivery system for augmented gastroparesis therapy:Formulation development and evaluation显示文摘The intention behind the present work was to develop a microsponge based novel dosage form for sustained delivery of domperidone.Quasi-emulsion solvent diffusion method was employed using Eudragit RS-100 with various drug-polymer ratios for the preparation of microsponges.For optimization purposes,several factors which affect microparticles’physical properties were investigated.Characterization techniques followed for the formed microsponges were DSC,FTIR,SEM,XRD and particle size analysis,along with morphology,drug loading and in vitro drug release.It was found that there were no chemical interactions between drugs and polymers used as per DSC and FTIR results.The drug-polymer ratio showed remarkable impact on drug content,encapsulation efficiency and particle size.SEM micrographs revealed that microsponges were spherical in shape with porous surface,and had 104±0.22μm mean particle size.The microsponges were then loaded in capsules followed by in vitro drug release study;which depicted that microsponges with drug-polymer ratio of 1:2 were more proficient to give extended drug release of 76.38%at the end of 8 h,superior in contrast to conventional marketed formulation Domstal®,which got exhausted incredibly earlier by releasing 82.57%drug at the end of 1⁄2 h only.Hence,the developed microsponge based formulation of domperidone would be an expectant,promising substitute to conventional therapy of gastroparesis,emesis and alike gastric ailments.Riyaz Ali M.Osmani Nagesh H.Aloorkar Bharati U.Thaware Parthasarathi K.Kulkarni Afrasim Moin Umme Hani Atul Srivastava Rohit R.Bhosale 2015Asian Journal of Pharmaceutical Sciences2015,10,5:1
3Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders显示文摘S. K.Kulkarni AshishDhir 2010Phytother. Res2010,,3:1
4Mesoporous cadmium bismuth niobate(CdBi2Nb2O9)nanospheres for hydrogen generation under visible light显示文摘Herein, we report visible light active mesoporous cadmium bismuth niobate(CBN) nanospheres as a photocatalyst for hydrogen(H_2) generation from copious hydrogen sulfide(H_2S). CBN has been synthesized by solid state reaction(SSR) and also using combustion method(CM) at relatively lower temperatures.The as-synthesized materials were characterized using different techniques. X-ray diffraction analysis shows the formation of single phase orthorhombic CBN. Field emission scanning electron microscopy and high resolution-transmission electron microscopy showed the particle size in the range of ~0.5–1 μm for CBN obtained by SSR and 50–70 nm size nanospheres using CM, respectively. Interestingly, nanospheres of size 50–70 nm self assembled with 5–7 nm nanoparticles were observed in case of CBN prepared by CM.The optical properties were studied using UV–visible diffuse reflectance spectroscopy and showed band gap around ~3.0 eV for SSR and 3.1 eV for CM. The slight shift in band gap of CM is due to nanocrystalline nature of material. Considering the band gap in visible region, the photocatalytic activity of CBN for hydrogen production from H_2S has been performed under visible light. CBN prepared by CM has shown utmost hydrogen evolution i.e. 6912 μmol/h/0.5 g which is much higher than CBN prepared using SSR.The enhanced photocatalytic property can be attributed to the smaller particle size, crystalline nature,high surface area and mesoporous structure of CBN prepared by combustion method. The catalyst was found to be stable, active and can be utilized for water splitting.Aniruddha K.Kulkarni Yogesh A.Sethi Rajendra P.Panmand Latesh K.Nikam Jin-Ook Baeg N.R.Munirathnam Anil V.Ghule Bharat B.Kale 2017Journal of Energy Chemistry2017,26,3:1
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