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| 1 | Staging accuracy of esophageal cancer by endoscopic ultrasound:A meta-analysis and systematic review显示文摘AIM: To evaluate the accuracy of endoscopic ultrasound (EUS) in the staging of esophageal cancer. METHODS: Only EUS studies confirmed by surgery were selected. Articles were searched in Medline and Pubmed. Two reviewers independently searched and extracted data. Meta-analysis of the accuracy of EUS was analyzed by calculating pooled estimates of sensitivity, specificity, likelihood ratios, and diagnostic odds ratio. Pooling was conducted by both the Mantel-Haenszel method (fixed effects model) and DerSimonian Laird method (random effects model). The heterogeneity of studies was tested using Cochran’s Q test based upon inverse variance weights. RESULTS: Forty-nine studies (n = 2558) which met the inclusion criteria were included in this analysis. Pooled sensitivity and specificity of EUS to diagnose T1 was 81.6% (95% CI: 77.8-84.9) and 99.4% (95% CI: 99.0-99.7), respectively. To diagnose T4, EUS had a pooled sensitivity of 92.4% (95% CI: 89.2-95.0) and specificity of 97.4% (95% CI: 96.6-98.0). With Fine Needle Aspiration (FNA), sensitivity of EUS to diagnose N stage improved from 84.7% (95% CI: 82.9-86.4) to 96.7% (95% CI: 92.4-98.9). The P value for the χ2 test of heterogeneity for all pooled estimates was > 0.10. CONCLUSION: EUS has excellent sensitivity and specificity in accurately diagnosing the TN stage of esophageal cancer. EUS performs better with advanced (T4) than early (T1) disease. FNA substantially improves the sensitivity and specificity of EUS in evaluating N stage disease. EUS should be strongly considered for staging esophageal cancer. | Srinivas R Puli Jyotsna BK Reddy Matthew L Bechtold Daphne Antillon Jamal A Ibdah Mainor R Antillon | 2008 | World Journal of Gastroenterology2008，14，10： | 55 |
| 2 | How good is endoscopic ultrasound for TNM staging of gastric cancers? A meta-analysis and systematic review显示文摘AIM: To evaluate the accuracy of endoscopic ultrasound (EUS) for staging of gastric cancers. METHODS: Only EUS studies confirmed by surgery were selected. Only studies from which a 2 × 2 table could be constructed for true positive, false negative, false positive and true negative values were included. Articles were searched in Medline, Pubmed, Ovid journals, Cumulative index for nursing & allied health literature, International pharmaceutical abstracts, old Medline, Medline nonindexed citations, and Cochrane control trial registry. Two reviewers independently searched and extracted data. The differences were resolved by mutual agreement. 2 × 2 tables were constructed with the data extracted from each study. Meta-analysis for the accuracy of EUS was analyzed by calculating pooled estimates of sensitivity, specifi city, likelihood ratios, and diagnostic odds ratio. Pooling was conducted by both the Mantel-Haenszel method (fi xed effects model) and DerSimonian Laird method (random effects model). The heterogeneity of studies was tested using Cochran's Q test based upon inverse variance weights. RESULTS: Initial search identified 1620 reference articles and of these, 376 relevant articles were selected and reviewed. Twenty-two studies (n = 1896) which met the inclusion criteria were included in this analysis. Pooled sensitivity of T1 was 88.1% (95% CI: 84.5-91.1) and T2 was 82.3% (95% CI: 78.2-86.0). For T3, pooled sensitivity was 89.7% (95% CI: 87.1-92.0). T4 hada pooled sensitivity of 99.2% (95% CI: 97.1-99.9). For nodal staging, the pooled sensitivity for N1 was 58.2% (95% CI: 53.5-62.8) and N2 was 64.9% (95% CI: 60.8-68.8). Pooled sensitivity to diagnose distant metastasis was 73.2% (95% CI: 63.2-81.7). The P for chi-squared heterogeneity for all the pooled accuracy estimates was > 0.10. CONCLUSION: EUS results are more accurate with advanced disease than early disease. If EUS diagnoses advanced disease, such as T4 disease, the patient is 500 times more likely to have true anatomic stage of T4 disease. | Srinivas Reddy Puli Jyotsna Batapati Krishna Reddy Matthew L Bechtold Mainor R Antillon Jamal A Ibdah | 2008 | World Journal of Gastroenterology2008，14，25： | 33 |
| 3 | Endoscopic ultrasound:It’s accuracy in evaluating mediastinal lymphadenopathy? A meta-analysis and systematic review显示文摘AIM:To evaluate the accuracy of endoscopic ultrasound (EUS), EUS-fine needle aspiration (FNA) in evaluating mediastinal lymphadenopathy. METHODS:Only EUS and EUS-FNA studies confirmed by surgery or with appropriate follow-up were selected. Articles were searched in Medline, Pubmed, and Cochrane control trial registry. Only studies from which a 2 × 2 table could be constructed for true positive, false negative, false positive and true negative values were included. Two reviewers independently searched and extracted data. The differences were resolved by mutual agreement. Meta-analysis for the accuracy of EUS was analyzed by calculating pooled estimates of sensitivity, specificity, likelihood ratios, and diagnostic odds ratios. Pooling was conducted by both Mantel-Haenszel method (fixed effects model) and DerSimonian Laird method (random effects model). The heterogeneity of studies was tested using Cochran’s Q test based upon inverse variance weights. RESULTS:Data was extracted from 76 studies (n = 9310) which met the inclusion criteria. Of these, 44 studies used EUS alone and 32 studies used EUS-FNA. FNA improved the sensitivity of EUS from 84.7% (95% CI:82.9-86.4) to 88.0% (95% CI:85.8-90.0). With FNA, the specificity of EUS improved from 84.6% (95% CI:83.2-85.9) to 96.4% (95% CI:95.3-97.4). The P forchi-squared heterogeneity for all the pooled accuracy estimates was > 0.10. CONCLUSION:EUS is highly sensitive and specific for the evaluation of mediastinal lymphadenopathy and FNA substantially improves this. EUS with FNA should be the diagnostic test of choice for evaluating mediastinal lymphadenopathy. | Srinivas R Puli Jyotsna Batapati Krishna Reddy Matthew L Bechtold Jamal A Ibdah Daphne Antillon Shailender Singh Mojtaba Olyaee Mainor R Antillon | 2008 | World Journal of Gastroenterology2008，14，19： | 10 |
| 4 | Complications in Acute Stroke in India(CASTI-I):a multicenter study显示文摘 | Pandian J D Kaur A Jyotsna R | 2011 | J Stroke Cerebrovasc Dis2011，25，5： | 1 |
| 5 | An Unusual Case of Large Posterior Fossa Neurenteric Cyst Involving Bilateral Cerebellopontine Angle Cisterns:Report of a Rare Case and Review of Literature 显示文摘 | Arora R Jyotsna Rani Y Uppin MS | 2014 | Pol J Radiology2014，79，： | 1 |
| 6 | Effect of physical and chemical reatments on domancy breaking germination and vigour of certain medicinal显示文摘 | Mohank K Reddya R Sharma S Jyotsna B | 2012 | Journal of Pharmacognosy2012，3，2： | 1 |
| 7 | Premorbid nutrition and short term outcome of stroke:a multicentre study from India显示文摘 | Pandian JD Jyotsna R Singh R | | 0，，： | 1 |
| 8 | Alveograph as a tool to assess the quality characteristics of wheat flour for parotta mak- ing显示文摘 | Indrani D Sai Manohar R Jyotsna Rajiv G | 1989 | Cereal Chem1989，66，： | 1 |
| 9 | Effect of whey protein concentrate on the rheological and baking properties of eggless cake显示文摘 | JYOTSNA R SAI MANOHAR R 1NDRANI D | 2007 | International Journal Properties2007，，1： | 1 |
| 10 | Effect of hydrocolloids and emulsifiers on the rheological,microstruetural and quality characteristics of eggless cake显示文摘 | ASHWINI A JYOTSNA R INDRANI D | 2009 | Food Hydrocolloids2009，23，： | 1 |
| 11 | Effect of hydrocolloids and emulsifiers on the rheological, microstructural and quality characteristics of eggless cake显示文摘 | ASHWINI A JYOTSNA R INDRANI D | 2009 | Food Hydrocolloids2009，23，： | 1 |
| 12 | Effect of hydrocolloids and emulsifiers on the theological, microstructural and quality characteristics of eggless cake 显示文摘 | Ashwini A Jyotsna R Indrani D | 2009 | Food Hydrocolloids2009，23，3： | 1 |
| 13 | Improvement of rheological and baking properties of cake batters with emulsifier gels显示文摘 | Jyotsna R Prabhasankar P Indrani D | 2004 | Journal of Food Science2004，69，1： | 1 |
| 14 | Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation 显示文摘 | Manesh R Kenneth W Jyotsna Garg | 2011 | N Engl J Med2011，365，10： | 1 |
| 15 | Alveograph as a tool to assess the quality characteristics of wheat flour for parotta making 显示文摘 | INDRANI D SAI MANOHAR R JYOTSNA RAJIV G | 2007 | Journal of Food Engineering2007，78，4： | 1 |
| 16 | Occupational exposure to sharp instrument injuries among dental, medical and nursing students in mahatma gandhi mission's campus, navi mumbai, india显示文摘 | JUVERIA H SABITA R JYOTSNA G | 2012 | Journal of Contemporary Dentistry2012，2，2： | 1 |
| 17 | Effect of replacement of fat with sesame oil and additives on rheological,microstructural,quality characteristics and fatty acid profile of cakes显示文摘 | Sowmya M Jeyarani T Jyotsna R | 2009 | Food Hydrocolloids2009，23，7： | 1 |
| 18 | Premorbid nutrition and short term outcome of stroke: a multicentre study from India显示文摘 | Pandian JD Jyotsna R Singh R | 2011 | J Neurol Neurosurg Psychiat2011，82，： | 1 |
| 19 | Effect of hydrocolloids and emulsifiers on the rheological,microstructural and quality characteristics of eggless cake显示文摘 | Ashwini A Jyotsna R Indrani D | 2009 | Food Hydrocolloids2009，23，3： | 1 |
| 20 | Effect of replacement of fat with sesame oil and additives on rheological,microstructure,quality characteristics and fatty acid profile of cakes显示文摘 | SOWMYA M JEYARANI T JYOTSNA R | | 0，，： | 1 |
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