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| 1 | Waist Circumference Reference Values for Screening Cardiovascular Risk Factors in Chinese Children and Adolescents显示文摘Objectives To explore the optimal threshold values of waist circumference(WC)for detecting cardiovascular(CV)risk factors among Chinese children and adolescents.Methods Association of WC with CV risk factors was studied among 65 898 children aged 7-18 years whose data were pooled from nine previous studies in China.CV risk factors in this study included hypertension(blood pressure above 95 percentile levels),dyslipidemia(with one or more of the following three indexes:TG≥1.7 mmol/L,TC≥5.18 mmol/L,and HDL-C≤1.04 mmol/L)and elevated glucose level(fasting plasma glucose ≥5.6 mmol/L).Receive-operating characteristic analysis(ROC)and logistic regression were employed to derive optimal age-and sex-specific waist circumference references for predicting CV risk factors.Results A slight increasing trend of CV risk factors was observed starting from the 75th percentile of waist circumference in the study population,while a remarkable increasing trend occurred from the 90th percentile.The optimal waist circumference thresholds for predicting high blood pressures were at the 75th percentile for both boys and girls,which was at the 90th percentiles for detecting at least two of the above three CV risk factors.In comparison with children with waist circumference below the 75th percentile,the odds ratio of two CV risk factors doubled among children with waist circumference between the 75th and the 90th percentile,and increased by 6 times among children with waist circumference above the 90th percentile.The trend of high blood pressure increasing with waist circumference remained significant after having been stratified by BMI category.Conclusion The 75th and the 90th percentiles of WC are the optimal cut-off points for predicting an increased and a substantially increased risk of CV factors in Chinese children and adolescents,respectively. | GUAN-SHENG MA CHENG-YE JI JUN MA JIE MI R1TA YT SLING FENG XIONG WEI-LI YAN XIAO-QI HU YAN-PING LI SONG-M1NG DU HONG-YUN FANG AND J1NG-XIONG JIANG | 2010 | Biomedical and Environmental Sciences2010，23，1： | 25 |
| 2 | Waist Circumference Distribution of Chinese School-age Children and Adolescents显示文摘Background Waist circumference(WC),a proxy measure of central body fat,is a better predictor than overall body fat for cardiovascular risk factors in both adults and children.WC cutoffs have been established in many countries,but the national WC reference has not been developed in China.Objective To study the distribution of WC in a representative group of Chinese children for establishing Chinese WC cutoff points.Methods Cross-sectional data obtained from 15 mainland provinces and Hong Kong were collected.There were 160 225 children and adolescents aged 7-18 years old in total.The subjects were divided into five regional groups namely costal city,other city,north rural,south rural,and Hong Kong,for analyzing the distribution of WC.Results A large variation in WC distribution was found among the five groups for both sexes.Coastal city group had the highest P85 WC values consistently from the early school ages to 18-year-old compared with other groups.In contrast,south rural group had P85 values consistently lagged behind not only the city groups but also the north rural group.Hong Kong group had a high P85 WC at early ages,but because of the smaller increments of WC during adolescence,the P85 curve was gradually exceeded by the north rural groups.Catch-up trend was found in the two rural groups since the peak of puberty.These disparities were caused by not only socioeconomic and urban-rural factors but also north-south differences.Because of the regional variation of WC,a 'gradient' prevalence of central obesity was prospected among these groups.Comparisons of WC distributions between the Chinese and the U.S.A or Netherlands demonstrated the necessary of setting up China's own WC cutoffs.Sex and age-specific percentiles were obtained and smoothed by using LMS method.Conclusion The data obtained from this study could be used to develop national WC cutoff points for Chinese children and adolescents. | CHENG-YE JI RITA YT SUNG GUAN-SHENG MA JUN MA ZHONG-HU HE TIAN-JIAO CHEN | 2010 | Biomedical and Environmental Sciences2010，23，1： | 22 |
| 3 | Barrier properties of TiN/TiSi2 bilayers formed by two-step rapid thermal conversion process for Cu diffusion barrier显示文摘 | Kim YT Jun CH Kim DY | 1999 | Thin Solid Films1999，347，2： | 1 |
| 4 | In vitro effects of ciprofloxacin and roxithromycin on apoptosis of jurkat T lymphocytes 显示文摘 | Jun YT Kim HJ Song MJ | 2003 | Antimicrob Agents Chemother2003，47，3： | 1 |
| 5 | In vitro effects of ciprofloxacin androxithromycin on apoptosis of jurkat T lymphocytes显示文摘 | Jun YT Kim HJ Song MJ | 2003 | AntimicrobAgents Chemother2003，47，： | 1 |
| 6 | In vitro effects of ciprofloxacin and roxithromycin on apoptosis of jurkat T lymphocytes显示文摘 | Kim HJ Song MJ | 2003 | Antimicrob Agents Chemother2003，47，： | 1 |
| 7 | Role of the human and murine cyclin T proteins in regulating HIV-1 tat-activation显示文摘 | Kwak YT Ivanov D Guo Jun | 1999 | J Mol Biol1999，288，1： | 1 |
| 8 | In vitro effects of ciprofloxacin and roxithromycin on apoptosis ofjurkat T lymphocytes显示文摘 | Jun YT Kim HJ Song MJ | 2003 | Antimicrob Agents Chemother2003，47，3： | 1 |
| 9 | The green tea polyphenol (-) -epigallocatechin gallate attemuates β-amyloid-induced neurotoxicity in cultured hippocampa neurons显示文摘 | Choi YT Jun CH Lee SR | 2001 | Life Sci2001，70，5： | 1 |
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