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您的检索式：作者名="Jumpei Ueda"
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| 1 | Ig SF11 regulates osteoclast differentiation through association with the scaffold protein PSD-95显示文摘Osteoclasts are multinucleated, giant cells derived from myeloid progenitors. While receptor activator of NF-κB ligand(RANKL)stimulation is the primary driver of osteoclast differentiation, additional signaling further contributes to osteoclast maturation.Here, we demonstrate that immunoglobulin superfamily member 11(Ig SF11), whose expression increases during osteoclast differentiation, regulates osteoclast differentiation through interaction with postsynaptic density protein 95(PSD-95), a scaffold protein with multiple protein interaction domains. Ig SF11 deficiency in vivo results in impaired osteoclast differentiation and bone resorption but no observed defect in bone formation. Consequently, Ig SF11-deficient mice exhibit increased bone mass.Using in vitro osteoclast culture systems, we show that Ig SF11 functions through homophilic interactions. Additionally, we demonstrate that impaired osteoclast differentiation in Ig SF11-deficient cells is rescued by full-length Ig SF11 and that the Ig SF11-PSD-95 interaction requires the 75 C-terminal amino acids of Ig SF11. Our findings reveal a critical role for Ig SF11 during osteoclast differentiation and suggest a role for Ig SF11 in a receptor-and signal transduction molecule-containing protein complex. | Hyunsoo Kim Noriko Takegahara Matthew CWalsh Sarah AMiddleton Jiyeon Yu Jumpei Shirakawa Jun Ueda Yoshitaka Fujihara Masahito Ikawa Masaru Ishii Junhyong Kim Yongwon Choi | 2020 | Bone Research2020，8，1： | 1 |
| 2 | Scintillation and optical properties of Ce-doped YAGG transparent ceramics显示文摘We investigated photoluminescence(PL) and scintillation properties of Ce^(3+)-doped Y_3Al_2Ga_3O_(12)(Ce:YAGG) transparent ceramics synthesized by vacuum sintering with different Ce^(3+) concentrations(mol.%) from 0.3% to 1%(0.3%Ce:YAGG, 0.5%Ce:YAGG, 0.8%Ce:YAGG and 1%Ce:YAGG). The samples were synthesized by the vacuum sintering technique. The obtained samples showed a very strong and broad PL emission by the 5d1-4f transition of Ce^(3+) in the wavelength range from 470 to 600 nm. The PL decay profiles were approximated by a single exponential decay function with the time constants of around 33–39 ns. Furthermore, the scintillation spectra induced by X-rays showed similar features with those observed in PL. The scintillation decay time profiles followed a second-order exponential decay function. The fast component group(ranged 35–42 ns) were dominantly contributed by the 5d_1-4f transition of Ce^(3+). The pulse height spectra utilizing the latter emissions showed a clear photoabsorption peak. Among those samples tested, 0.5%Ce:YAGG sample showed the highest scintillation light yield of 21,400 ph/MeV under ^(137)Cs γ-ray irradiation. | Masaki Mori Jian Xu Go Okada Takayuki Yanagida Jumpei Ueda Setsuhisa Tanabe | 2016 | Journal of Rare Earths2016，34，8： | 1 |
| 3 | Preparation and optical property of glass ceramics containing ruby crystals显示文摘 | Ueda Jumpei Tanabe Setsuhisa | 2010 | Journal of the American Ceramic Society2010，93，10： | 1 |
| 4 | 利用电荷转移工程提高红色SrLa(Sc,Ga)O_(4):Ce^(3+)荧光粉的热稳定性显示文摘可被蓝光激发的高热稳定性红色荧光粉是制作高性能白光二极管(WLED)的关键材料.研究发现,Ce^(3+)掺杂的SrLaScO_(4)(SLO:Ce^(3+))荧光粉在440 nm激发下呈现峰值为640 nm的反常宽带红光发射.光谱学和结构分析证实Ce^(3+)离子在SLO中进入[LaO_(8)]多面体,产生强的晶体场劈裂和较大的Stokes位移,实现了比Eu^(2+)更低能量的红光发射.我们还设计并揭示了一种电荷转移相互作用的策略:在Sc^(3+)位置引入电负性较大的Ga^(3+),Ga^(3+)可以吸引更多邻位配合基团的电荷,以减少导带底部的电子占用而扩大带隙.Sc/Ga取代有效地抑制了热激活电离过程,使SrLa(Sc,Ga)O_(4):Ce^(3+)的热稳定性获得了显著提升,即在150℃的发光强度比(相对于20℃)从15%提升至31%.本研究为发现具有良好热稳定性的新型Ce^(3+)掺杂红色荧光粉提供了有效的设计原则. | 杨至雨 赵逸飞 Jumpei Ueda Maxim S.Molokeev 尚蒙蒙 夏志国 | 2023 | Science China Materials2023，66，5： | 0 |
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