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3篇 您的检索式：作者名="Jonathan Yap"

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		题名	作者	年代	出处	被引量
	1	UNDERSTANDING THE MECHANICAL PROPERTIES OF SINGLE MICRO-PARTICLES AND THEIR COMPACTION BEHAVIOUR显示文摘The compaction of particulate materials to form tablets is increasingly employed as a final dosage form for functional products due to its simplicity and low cost. However, the functionality of some products may be impaired due to the high compression pressures required. The general aim of the current study is to understand the relationship between the mechanical properties of single feed particles (< 100 μm) and their compaction behaviour in order to produce tablets at low compression pressure with acceptable strength. The materials studied were pharmaceutical excipients, comprising three enteric polymer particles and three different powders in the form of agglomerates. The mechanical properties of the individual particles or agglomerates were determined by a micromanipulation technique. The samples were also com- pacted in cylindrical tableting dies. It was observed that there was a strong correlation between the forces required to cause the fracture of the single particles and those derived from the compaction measurements as determined using an existing analysis.	Siaw Fung Yap Michael Adams Jonathan Seville Zhibing Zhang	2006	China Particuology2006，4，1：	2
	2	Efficacy and Safety of Regorafenib in Patients With Metastatic and/or Unresectable GI Stromal Tumor After Failure of Imatinib and Sunitinib: A Multicenter Phase II Trial显示文摘	Suzanne George Qian Wang Michael C. Heinrich Christopher L. Corless Meijun Zhu James E. Butrynski Jeffrey A. Morgan Andrew J. Wagner Edwin Choy William D. Tap Jeffrey T. Yap Annick D. Van den Abbeele Judith B. Manola Sarah M. Solomon Jonathan A. Fletcher	2012	Journal of Clinical Oncology2012，，19：	1
	3	Catheter abla?tion of ventricular fibrillation storm in a long QT syndrome geno?type carrier with normal QT interval显示文摘	Jonathan Yap MBBS MRCP Vern Hsen Tan	2013	Singapore Med J2013，，：	1

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