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2篇 您的检索式：作者名="Joe E. Springer"

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		题名	作者	年代	出处	被引量
	1	Targeting the mitochondrial permeability transition pore in traumatic central nervous system injury显示文摘The mitochondrion serves many functions in the central nervous system(CNS) and other organs beyond the well-recognized role of adenosine triphosphate(ATP) production. This includes calcium-dependent cell signaling, regulation of gene expression, synthesis and release of cytotoxic reactive oxygen species, and the release of cytochrome c and other apoptotic cell death factors. Traumatic injury to the CNS results in a rapid and, in some cases, sustained loss of mitochondrial function. One consequence of compromised mitochondrial function is induction of the mitochondrial permeability transition(mPT) state due to formation of the cyclosporine A sensitive permeability transition pore(mPTP). In this mini-review, we summarize evidence supporting the involvement of the mPTP as a mediator of mitochondrial and cellular demise following CNS traumatic injury and discuss the beneficial effects and limitations of the current experimental strategies targeting the mPTP.	Joe E. Springer Pareshkumar Prajapati Patrick G. Sullivan	2018	Neural Regeneration Research2018，13，8：	3
	2	Neuroprotection and Acute Spinal Cord Injury: A Reappraisal显示文摘	Edward D. Hall Joe E. Springer	2004	NeuroRX2004，，1：	1

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