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| 1 | Trends of foodborne diseases in China: lessons from laboratory- based surveillance since 2011显示文摘Foodborne 疾病是世界范围的最重要的公共健康问题之一。中国在食物链的所有方面面对各种各样、崭新的挑战。从从 2013 ~ 2016 的基于实验室的 foodborne 疾病监视系统的数据,以及不同区域和年龄,能在与多样的特征检测的病原体的模式与差别一起被发现。Vibrio parahaemolyticus 是在中国的传染腹泻的领先的原因,特别在在沿海的区域的成年人之中。沙门氏菌是为实质的社会经济的负担负责的严肃、广泛地分布式的病原体。Shigella 主要在 5 年下面在孩子之中与开发更少的区域在西北中国和内陆省(河南省) 被识别。从从 2011 ~ 2016 报导系统的 foodborne 疾病爆发的数据证明有毒的动物和为大多数死亡负责的植物因素在在西南区域的遥远的区域是有毒的蘑菇(54.7%) 。引起了报导的大多数案例(42.3%) 的生物危险被归因于 V。parahaemolyticus, foodborne 爆发的领先的原因。在这评论,我们在中国总结最近的监视途径到 foodborne 疾病并且在发达国家把结果与那些作比较。 | Jikai Liu Li Bai Weiwei Li Haihong Han Ping Fu Xiaochen Ma Zhenwang Bi Xiaorong Yang Xiuli Zhang Shiqi Zhen Xiaoling Deng Xiumei Liu Yunchang Guo | 2018 | Frontiers of Medicine2018，12，1： | 55 |
| 2 | Mushroom Poisoning Outbreaks—China,2010–2020显示文摘ABSTRACT Introduction:Mushroom poisoning was the leading cause of foodborne disease outbreaks and outbreak-associated deaths in China.Mushroom poisoning outbreak surveillance can provide insight into the epidemiological characteristics of mushroom poisonings and guide policymaking and health education to reduce illnesses and deaths.Methods:Foodborne Disease Outbreak Surveillance System was upgraded in 2011 to collect foodborne disease outbreaks in China.Mushroom poisoning outbreaks during 2010–2020 were selected to analyze geographical distribution,seasonal distribution,and setting of food preparation.Results:A total of 10,036 outbreaks,which resulted in 38,676 illnesses and 788 deaths,were reported in this period.Mushroom poisonings occurred all over the country,but with highest incidence in the southwest and central China. | Weiwei Li Sara M.Pires Zhitao Liu Jinjun Liang Yafang Wang Wen Chen Chengwei Liu Jikai Liu Haihong Han Ping Fu Yunchang Guo | 2021 | China CDC weekly2021，3，24： | 18 |
| 3 | Characteristics of Settings and Etiologic Agents of Foodborne Disease Outbreaks—China,2020显示文摘Introduction:Foodborne diseases are a growing public health problem and have caused a large burden of disease in China.This study analyzed epidemiological characteristics of foodborne diseases in China in 2020 to provide a scientific basis for prevention and control measures.Methods:Data were collected from 30 of 31 provincial-level administrative divisions(PLADs)in the mainland of China,excluding Xizang(Tibet)Autonomous Region,via the National Foodborne Disease Outbreaks Surveillance System・The number and proportion of outbreaks,illnesses,hospitalizations,deaths by setting,pathogen-food category pairs and etiology were calculated.Results:In 2020,7,073 foodborne disease outbreaks were reported,resulting in 37,454 illnesses and 143 deaths.Among the identified pathogens,microbial pathogens were the most common confirmed etiology,accounting for 41.7%of illnesses.Poisonous mushrooms caused the largest proportion of outbreaks(58.0%)and deaths(57.6%).For venues where foodborne disease outbreaks occur,household had the highest number of outbreaks(4,140)and deaths(128),and catering service locations caused the largest proportion of illnesses(59.9%).Outbreaks occurring between June and September accounted for 62.8%of total outbreaks.Conclusions:Foodborne disease outbreaks mainly occurred in households・Microbial pathogens remained the top cause of outbreak-associated illnesses.Poisonous mushrooms were ranked the top cause of deaths in private homes in China.The supervision and management of food safety and health education should be strengthened to reduce the burden of foodborne diseases・Publicity should be increased to reduce the incidence of mushroom poisonings in families,and supervision and management of food should be strengthened to reduce microbial contamination. | Hongqiu Li Weiwei Li Yue Dai Yuyan Jiang Junhua Liang Santao Wang Maoqiang Zhuang Zheng Huang Lizi Xu Bo Xue Jikai Liu Haihong Han Sara M.Pires Ping Fu Yunchang Guo | 2021 | China CDC weekly2021，3，42： | 14 |
| 4 | Tomato SlAN11 regulates flavonoid biosynthesis and seed dormancy by interaction with bHLH proteins but not with MYB proteins显示文摘The flavonoid compounds are important secondary metabolites with versatile human nutritive benefits and fulfill a multitude of functions during plant growth and development.The abundance of different flavonoid compounds are finely tuned with species-specific pattern by a ternary MBW complex,which consists of a MYB,a bHLH,and a WD40 protein,but the essential role of SlAN11,which is a WD40 protein,is not fully understood in tomato until now.In this study,a tomato WD40 protein named as SlAN11 was characterized as an effective transcription regulator to promote plant anthocyanin and seed proanthocyanidin(PA)contents,with late flavonoid biosynthetic genes activated in 35S::SlAN11 transgenic lines,while the dihydroflavonol flow to the accumulation of flavonols or their glycosylated derivatives was reduced by repressing the expression of SlFLS in this SlAN11-overexpressed lines.The above changes were reversed in 35S::SlAN11-RNAi transgenic lines except remained levels of flavonol compounds and SlFLS expression.Interestingly,our data revealed that SlAN11 gene could affect seed dormancy by regulating the expressions of abscisic acid(ABA)signaling-related genes SlABI3 and SlABI5,and the sensitivity to ABA treatment in seed germination is conversely changed by SlAN11-overexpressed or-downregulated lines.Yeast two-hybrid assays demonstrated that SlAN11 interacted with bHLH but not with MYB proteins in the ternary MBW complex,whereas bHLH interacted with MYB in tomato.Our results indicated that low level of anthocyanins in tomato fruits,with low expression of bHLH(SlTT8)and MYB(SlANT1 and SlAN2)genes,remain unchanged upon modification of SlAN11 gene alone in the transgenic lines.These results suggest that the tomato WD40 protein SlAN11,coordinating with bHLH and MYB proteins,plays a crucial role in the fine adjustment of the flavonoid biosynthesis and seed dormancy in tomato. | Yongfeng Gao Jikai Liu Yongfu Chen Hai Tang Yang Wang Yongmei He Yongbin Ou Xiaochun Sun Songhu Wang Yinan Yao | 2018 | Horticulture Research2018，5，1： | 13 |
| 5 | The Intronic cis Element SE1 Recruits trans-Acting Repressor Complexes to Repress the Expression of ELONGATED UPPERMOST INTERNODE1 in Rice显示文摘 | Yongyao Xie Yaling Zhang Jingluan Han Jikai Luo Gousi Li Jianle Huang Haibin WU Qingwei Tian Qinlong Zhu Yuanling Chen Yoji Kawano Yao-Guang Liu Letian Chen | 2018 | Molecular Plant2018，11，5： | 3 |
| 6 | Genome-wide analysis of WRKY transcription factors in Solanum lycopersicum显示文摘 | Shengxiong Huang Yongfeng Gao Jikai Liu Xiaoli Peng Xiangli Niu Zhangjun Fei Shuqing Cao Yongsheng Liu | 2012 | Molecular Genetics and Genomics2012，，6： | 3 |
| 7 | Prevalence of Antimicrobial Resistant of Vibrio parahaemolyticus Isolated from Diarrheal Patients——Six PLADs,China,2016−2020显示文摘Summary What is already known on this topic?Vibrio parahaemolyticus(V.parahaemolyticus)is frequently resistant to common antimicrobials such as ampicillin and generally highly susceptible to most clinically used antimicrobials.What is added by this report?V.parahaemolyticus were highly resistant to cefazolin and ampicillin:94.4% and 37.0%,respectively. | Haihong Han Sara MPires Johanne Ellis-Iversen Zhen Tang Xiaoai Zhang Jikai Liu Weiwei Li Qingpo Cui Jing Zou Ping Fu Yunchang Guo | 2021 | China CDC weekly2021，3，29： | 2 |
| 8 | Antioxi- dant activities of three dihydrochalcone glucosides from leaves of lithocarpus pachyphyllus显示文摘 | Yang Weimin Liu Jikai Qin Xiangdong | 2004 | Z Naturforsch2004，59，： | 1 |
| 9 | 查看详情显示文摘 | Taicheng An Jikai Liu Guiying Li | | 0，，： | 1 |
| 10 | Differentiation and apoptosis in K562 crythroleukemia cells induced by Matrine 显示文摘 | Zhang Yan Jiang Jikai Liu xiaoshan | 1998 | Natural Medicine1998，52，4： | 1 |
| 11 | Dual-conductive metal-organic framework@MXene heterogeneity stabilizes lithium-ion storage显示文摘Although a few pristine metal-organic frameworks(MOFs) of graphene analogue topology exhibit high intrinsic electrical conductivity, their use in lithium-ion batteries(LIBs) is still hampered by unfavorable Li+adsorption energy(ΔEa). In this paper, an electroconductive ferrocene-based MOF@MXene heterostructure is built to provide stable anodes for Li+storage. Charge density difference and planar average potential charge density show substantial redistribution of charges at the interfaces, transferring from MXene to MOF layers. Moreover, density functional theory(DFT) calculations reveal that the interaction between MXene and MOF significantly increases the ΔEa. As a result, the heterostructure anode exhibits high capacities and outstanding cycling stability with a capacity retention of 80% after 5000 cycles at 5 A g^(-1), outperforming mono-component MXene and MOF. Furthermore, the heterostructure anode is built into a full cell with a commercial NCM 532 cathode, delivering a high energy density of 611 Wh kg^(-1)and power density of 7600 W kg^(-1). The developed conductive MOF@MXene heterogeneity for improved LIB offers valuable insights into the design of advanced electrode materials for energy storage. | Lanju Sun Honglei Wang Shengliang Zhai Jikai Sun Xu Fang Hongyan Yang Dong Zhai Chengcheng Liu Wei-Qiao Deng Hao Wu | 2023 | Journal of Energy Chemistry2023，，1： | 1 |
| 12 | Structural and photocatalytic degradation characteristics of hydrothermally treated mesoporous TiO 2显示文摘 | Taicheng An Jikai Liu Guiying Li Shanqing Zhang Huijun Zhao Xiangying Zeng Guoying Sheng Jiamo Fu | 2008 | Applied Catalysis A General2008，，2： | 1 |
| 13 | Production of biscuits by substitution with different ratios of yellow pea flour显示文摘To promote the commercialization of yellow pea flour(YPF)due to its nutritional benefits.Four biscuits with different YPF ratio(10%–50%)were conducted to explore the optimal addition percentage.The effects of YPF on the rheological and baking performance of biscuits were performed.The results showed that the substitution ratio of YPF and milling methods had a critical impact on the rheological properties of dough.The dough stability decreased graduallywhile a softening degree increased with YPF ratio increased.In a term of biscuits,the dimensions of length(L),width(W),thickness(T)and color(L*)of biscuits reduced as YPF addition ratio increased,while colors(a*and b*)and hardness apparently increased.In addition,milling methods had a great influence on the texture and sensory evaluation of four biscuits.The dimensions and color parameters of biscuits from fine flours were larger than that from coarse flours,whereas hardness from fine flours was relatively softer,indicating flour with fine particle size could accelerate the extension and expansion of dough network,and improve Maillard reaction during baking.The highest sensory score for short and tough biscuits was obtained given at YPF ratio of 30%without compromising the qualities of biscuits. | Jikai Zhao Xin Liu Xiang Bai Fengcheng Wang | 2019 | Grain & Oil Science and Technology2019，2，4： | 1 |
| 14 | Hereto- structured TiO2/WO3 porous microspheres: preparation, characterization and photocatalytic properties显示文摘 | Yang Jikai Zhang Xintong Liu Hong | 2013 | Cataly- sis Today2013，201，： | 1 |
| 15 | DPPH radical scavenging activity of ten natural p-terpbenyl derivatives obtained from three edible mushrooms indigenous to China 显示文摘 | Liu Jikai Hu Lin Dong Ze jun | 2004 | Chem Biodiversi2004，1，： | 1 |
| 16 | DON reduction of wheat grain without compromising the lab-scale milling properties of flour显示文摘Wheat branwas investigated to be themost commonly contaminated raw material by mycotoxins.However,there are no economical and practical pretreatment methods for industrial on-line application until now.The effect of light debranning on deoxynivalenol(DON)removal,polyphenol oxidase(PPO)activity and flour quality from lab-scale milling were performed.For on-line production,the DON concentration in wheat decreased 15.89%at debranning ratio of 1.2%.For lab experiment,the maximum DON removal for wheat and flour was 23.35%and 21.95%,respectively.However,the PPO activity,browning of dough sheet and flour qualities in lab scale exhibited no significant variation.Light debranning(1.2%)prior to milling could be efficiently applied to on-line wheat production. | Jikai Zhao Xin Liu Fengcheng Wang | 2019 | Grain & Oil Science and Technology2019，2，3： | 1 |
| 17 | Inhibitory effect of mycophenolate mofetil on human hepatocellular carcinoma cell line HepG-2显示文摘Objective:To investigate the inhibitory effect of mycophenolate mofetil on human hepatocellular carcinoma cell line HepG-2. Methods: HepG-2 cells were cultured in the presence of the different concentrations of mycophenolate mofetil in vitro. MTT assay was used to analyze the inhibition of cell viability conferred by mycophenolate mofetil. Cell apoptosis was observed using Hoechst33258 staining, and the percentage of HepG-2 cells at different cell cycles was determined through flow cytometry. The ability of cell adhesion was evaluated by in vitro adhesion assay. Gene expressions of factors (ICAM-1 and VCAM-1) were detected by RT-PCR. Results: Mycophenolate mofetil significantly inhibited the growth of HepG-2 cells by inducing the apoptosis of cells and this drug also inhibited the adhesion of HepG-2 cells in a dose-dependent manner. Marked morphological changes characterized in cell apoptosis were demonstrated through Hoechst33258 staining. In addition, mycophenolate mofetil decreased the proportion of S phase cells and increased that of G0/G1 phase cells. [3H]-Thymidine uptake assay indicated that the application of mycophenolate mofetil at different concentrations significantly inhibited the cell proliferation. RT-PCR identified the expression levels of ICAM-1 and VCAM-1 genes in liver cancer cells after cultured for 72 h with different concentrations of drug. An inverse relationship was found between the expressions of ICAM-1 and VCAM-1 and drug concentrations. Conclusion: Mycophenolate mofetil has remarkable inhibitory effect on hepatocarcinoma HepG-2 cells. | Chu Yankui Lu Jianguo Yin Jikai Cai Liang Liu Yi | 2009 | Journal of Medical Colleges of PLA(China)2009，24，4： | 1 |
| 18 | Preparation and characterization of highly active mesoporous Ti02 photocataiysts by hydrothermal synthesis under weak acid conditions显示文摘 | Liu Jikai An Taicheng Li Guiying Bao Ningzhong Sheng Guoying Fu Jiamo | 2009 | Microporous and Mesoporous Materials2009，124，： | 1 |
| 19 | Four sesquiterpene from the insecticidal pla-nt celastrus angulatus显示文摘 | LIU Jikai BECKER H ZAPP J | 1995 | Phytochemistry1995，40，3： | 1 |
| 20 | Effects of plumbagin on platelet aggregation and platelet- neutrophil interactions显示文摘 | Shen Zhiqiang Dong Zejun Chen Zhihe Liu Jikai | 2003 | Planta Medica2003，69，7： | 1 |
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