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73篇 您的检索式：作者名="Jethwa"

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	题名	作者	年代	出处	被引量
1	Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma显示文摘AIM: To characterise expression of known E-cadherin repressors; Snail, Slug and Twist in the development of esophageal adenocarcinoma. METHODS: E-cadherin, Slug, Snail and Twist mRNA expression in Barrett's metaplasia and esophageal adenocarcinoma specimens was examined by real-time reverse transcription-polymerase chain reaction (RT-PCR). Semi-quantitative immunohistochemistry was used to examine cellular localisation and protein levels. The effect of Slug on epithelial mesenchymal transition (EMT) markers was examined by transfection of Slug into an adenocarcinoma line OE33.RESULTS: Cellular localisation of Slug in Barrett's metaplasia was largely cytoplasmic whilst in adenocarcinoma it was nuclear. Semi-quantitative analysis indicated that Slug was more abundant in adenocarcinoma compared to matched Barrett's metaplastic specimens. Snail and Twist were expressed in adenocarcinoma but were cytoplasmic in location and not induced compared to Barrett's mucosa. These observations were supported by mRNA studies where only Slug mRNA was shown to be over-expressed in adenocarcinoma and inversely correlated to E-cadherin expression. Overexpression of Slug in OE33 mediated E-cadherin repression and induced the mesenchymal markers vimentin and fibronectin.CONCLUSION: Progression to adenocarcinoma is associated with increased Slug expression and this may represent a mechanism of E-cadherin silencing.	Paras Jethwa Mushal Naqvi Robert G Hardy Neil A Hotchin Sally Roberts Robert Spychal Chris Tselepis	2008	World Journal of Gastroenterology2008，14，7：	24
2	Development of the Hypertonia Assessment Tool (HAT): a discriminative tool for hypertonia in children 显示文摘	Jethwa A Mink J Macarthur C	2010	Dev Med Child Neurol2010，52，5：	1
3	Support Pressure Assessment in Arched Underground Openings Through Poor Rock Masses显示文摘	Singh B Goel R K Jethwa J L etc	1997	Engineering Geology1997，，48：	1
4	Correlation between Observed Support Pressure and Rock Mass Quality 显示文摘	Singh B Jethwa J L Dube A K etc	1992	Tunnelling and Underground Space Technology1992，，1：	1
5	Effects of joint orientation and rock mass quality on tunnel blasting显示文摘	CHAKRABORT A K JETHWA J L PAITHANKAR A G	1994	Engineering geology1994，37，3：	1
6	The use of air decks in production blasting in an open pit coal mine显示文摘	J. C. Jhanwar J. L. Jethwa	2000	Geotechnical and Geological Engineering2000，，4：	1
7	Next-generation sequencing of cancer consensus genes in lymphoma显示文摘	Hullein J Jethwa A Stolz T	2013	Leuk Lymphoma2013，54，：	1
8	Application of Air Decks in Production Blasting to Improve Fragmentation and Economics of an Open Pit Mine显示文摘	J.C. Jhanwar A.K. Cakraborty H.N. Anireddy J.L. Jethwa	1999	Geotechnical and Geological Engineering1999，，1：	1
9	Support pressure assessment in arched underground openings through poor rock masses显示文摘	BHAWANI SINGH GOEL R K JETHWA J L	1997	Engineering Geology1997，48，：	1
10	Influence of air - deck blasting on fragmentation in jointed rocks in an open - pit man- ganese mine 显示文摘	Jhanwar J C Jethwa J L Reddy A H	2000	Engineering Geology2000，57，2：	1
11	Support Pressure Assessment in Arched Underground Openings Through Poor Rock Masses 显示文摘	BHAWANI Singh CA)EL R K JETHWA J L	1997	Engineering Geology1997，，48：	1
12	Accuracy of computed tomographic angiography compared to digital subtraction angiography in the diagnosis of intracranial stenosis and its impact on clinical decision-making显示文摘	Duffis E J Jethwa P Gupta G	2013	J Stroke Cerebrovasc Dis2013，22，7：	1
13	The microbiological impact of pre-operative biliary drainage on patients undergoing hepato-bili- ary-pancreatic surgery 显示文摘	Jethwa P Breuning E Bhati C	2007	Aliment Pharmaeol Ther2007，25，10：	1
14	Development of the Hypertonia Assessment Tool (HAT):a discriminative tool for hypertonia in children显示文摘	Jethwa A Mink J Macarthur C	2010	Dev Med Child Neurol2010，52，5：	1
15	Endomembrane Ptdlns (3, 4, 5) P3 activates the PI3K-Akt pathway显示文摘	Jethwa N Chung GHC Lete MG	2015	Journal of cell science2015，128，18：	1
16	Effects of Joint Orientation and Rock Mass Quality on Tunmel Blastiny显示文摘	Chakraborty A K Jethwa J L Paithankar A G	1994	Engineering Geology1994，37，314：	1
17	Effect of Tunnel Depth on Modulus of Deformation of Rock Mass 显示文摘	Verman M Singh B Viladkar M N Jethwa JL	1997	Rock Mech Rock Eng1997，30，3：	1
18	Paraventricular nucleus administration of calcitonin gene-related peptide inhibits food intake and stimulates the hypothalamo-pituitary-adrenal axis显示文摘	DHILLO W S SMALL C J JETHWA P H	2003	Endocrinology2003，144，4：	1
19	Cost-effectiveness of digital subtraction angiography in the setting of computed tomographic angiography negative subarachnoid hemorrhage显示文摘	Jethwa PR Punia V Patel TD	2013	J Neurosurgery2013，72，4：	1
20	Comprehensive Load-Shedding System 显示文摘	JETHWA U K BANSAL R K DATEN	2010	IEEE Transactions on In- dustry App lication2010，46，2：	1

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