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| 1 | Drug eluting biliary stents to decrease stent failure rates:Areview of the literature显示文摘Biliary stenting is clinically effective in relieving both malignant and non-malignant obstructions. However, there are high failure rates associated with tumor ingrowth and epithelial overgrowth as well as internally from biofilm development and subsequent clogging. Within the last decade, the use of prophylactic drug eluting stents as a means to reduce stent failure has been investigated. In this review we provide an overview of the current research on drug eluting biliary stents. While there is limited human trial data regarding the clinical benefit of drug eluting biliary stents in preventing stent obstruction, recent research suggests promise regarding their safety and potential efficacy. | Joseph Shatzel Jisoo Kim Kartik Sampath Sharjeel Syed Jennifer Saad Zilla H Hussain Kabir Mody J Marc Pipas Stuart Gordon Timothy Gardner Richard I Rothstein | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，2： | 6 |
| 2 | OPG对TNF诱导的成骨细胞凋亡的抑制作用显示文摘目的 探讨TNF α能否诱导成骨类细胞凋亡及OPG能否抑制其凋亡 ,开辟一条防治骨质疏松的新路。方法 将人间充质干细胞在分化培养液中培养 2 1天使之成为成骨细胞 ,与MG6 3一起用于凋亡实验。鼠WEHI 16 4细胞系用于阳性对照。AnnexinV和TUNEL分析方法检测成骨类细胞凋亡。结果 和FasL诱导细胞凋亡一样 ,TNF α能引起MG6 3骨肉瘤细胞、间充质干细胞和成骨细胞的凋亡 ,并表现为明显的浓度依赖和时间依赖。低浓度TNF α(170~ 5 0 0 pmol/L)作用于细胞 2~ 4h就显示了较明显的凋亡 ,而 0 4 5~1 5nmol/LOPG几乎完全抑制了 5 0 0 pmol/LTNF α诱导的凋亡。结论 OPG能够抑制TNF α诱导的成骨类细胞凋亡。 | 步荣发 李亚男 Jennifer I Oakley Harry C Blair | 2004 | 解放军医学杂志2004，29，4： | 4 |
| 3 | Choice of laxatives and colonoscopic preparation in pregnant patients from the viewpoint of obstetricians and gastroenterologists显示文摘AIM: To elucidate the preferences of gastroenterologists at our institution and compare them to those of obstetricians when making decisions in the pregnant patient, including which type of bowel preparations to use for ? exible sigmoidoscopy or colonoscopy, as well as which laxatives can be used safely. METHODS: Surveys were mailed to all attending gastroenterologists (n = 53) and obstetricians (n = 99) at our institution. Each survey consisted of the 14 most common laxative or motility agents used in pregnancy and inquired about the physician’s prescribing habits in the past as well as their willingness to prescribe each medication in the future. The survey also listed four common bowel preparations used prior to colonoscopy and sigmoidoscopy and asked the physician to rank the order of the preferred agent in each case. RESULTS: With regard to common laxatives, both gastroenterologists and obstetricians favor the use of Metamucil, Colace, and Citrucel. Both groups appear to refrain from using Fleets Phosphosoda and Castor oil. Of note, obstetricians are less inclined to use PEG solution and Miralax, which is not the case with gastroenterologists. In terms of comparing bowel preparations for colonoscopy, 50% of gastroenterologists prefer to use PEG solution and 50% avoid the use of Fleets Phosphosoda. Obstetricians seem to prefer Fleets Phosphosoda (20%) and tend to avoid the use of PEG solution (26%). With regard to bowel preparation for sigmoidoscopy, both groups prefer Fleets enema the most (51%), while magnesium citrate is used least often (38%). CONCLUSION: It is clear that preferences in the use ofbowel cleansing preparations between the two groups exist, but there have not been many case controlled human studies in the pregnant patient that give clear cut indications for using one versus another drug. In light of the challenge of performing controlled trials in pregnant women, more extensive surveys should be undertaken to gather a larger amount of data on physicians’ experiences and individual preferences. | Jeevan Vinod Jennifer Bonheur Burton I Korelitz Georgia Panagopoulos | 2007 | World Journal of Gastroenterology2007，13，48： | 4 |
| 4 | BCL2 inhibits cell adhesion, spreading, and motility by enhancing actin polymerization显示文摘BCL2 最好作为多功能的 anti-apoptotic 蛋白质被知道。然而,很少在房间粘合剂和活动性事件对它的角色被知道。这里,我们证明 BCL2 可以在房间粘附的规定起一个作用,传播,并且活动性。BCL2 什么时候是在有教养的鼠科、人的房间线,传播的房间,粘附,和活动性的 overexpressed,被损害。与这些结果一致, Bcl2 的损失导致了在 Bcl2 空的老鼠观察的更高的活动性与野类型相比的胚胎的成纤维细胞(MEF ) 房间。房间粘附和活动性的 BCL2 规定的机制可以包含包含 BCL2,肌动朊,和 gelsolin 的建筑群的形成,它看起来机能上地减少 gelsolin 的切断的活动。我们观察到从 overexpressed BCL2 提高了的 MCF-7 和 NIH3T3 房间的 lysate 肌动朊聚合在在 vitro 试金没有房间。BCL2 和 F 肌动朊的共焦的 immunofluorescent 本地化在一致地传播期间证明 BCL2 的那增加的表情导致了增加的 F 肌动朊聚合。因此, BCL2 和 gelsolin 建筑群的形成(它可能包含另外的蛋白质) 看起来在房间粘附和移植的规定起一个关键作用。与癌症转移给房间活动性的确定的关联,这结果可以解释在一些肿瘤房间类型的 BCL2 的表示为什么为转移减少潜力并且与改进耐心的预后被联系。 | Hengning Ke Vandy I Parron Jeff Reece Jennifer Y Zhang Steven K Akiyama John E French | 2010 | Cell Research2010，20，4： | 3 |
| 5 | Mobile Ad Hoc networking:Imperatives and challenges显示文摘 | Chlamtac I Conti M Jennifer J N Liu | 2003 | Ad Hoc Networks2003，，1： | 1 |
| 6 | A comparison of myeorrhizal and saprotrophic fungus tolerance to creosote in vitro 显示文摘 | Dana L Jennifer I Aimee L | 2003 | Int Biode- ter Biodegr2003，51，3： | 1 |
| 7 | A direct reconstruction algorithm for electrical impedance tomography显示文摘 | Jennifer L M Samuli S David I | 2002 | IEEE Trans Med Imaging2002，21，6： | 1 |
| 8 | Comorbidity, Complications and Coding显示文摘 | Lisa I Lessoni Susan M Foley Jennifer Daley | 1992 | Bias Jama1992，，267： | 1 |
| 9 | Estrogen receptor beta modulatessynthesis of bone matrix proteins in human osteoblast-like MG63 cells 显示文摘 | LIHUAN C RONGFA B JENNIFER I | 2003 | J Cell Biochem2003，89，1： | 1 |
| 10 | Cancer history and other personal factors affect quality of life in patients with hepatitis C 显示文摘 | Sara H Sandy I Jennifer S | 2005 | Health and Quality of Life Outcomes2005，3，39： | 1 |
| 11 | Classical swine fever virus diversity and evolution显示文摘 | Paul L Georgina I Jennifer N | 1996 | J Gen Virol1996，77，： | 1 |
| 12 | A Rapid Method forlron Determination in Fortified Foods显示文摘 | Jennifer S Kosse A C Yeung A I | 2001 | Food Chemistry2001，，75： | 1 |
| 13 | Nitroxyl anion donor, angelig salt, does not develop tolerance in rat isolated aortae 显示文摘 | JENNIFER C I JOANNE L F ROBERT E W | 2007 | Hypertension2007，49，4： | 1 |
| 14 | Biochemical properties of a newly described Escherichia species,Escherichia albertii显示文摘 | ABBOTT SHARON L JENNIFER O'CONNOR TOM ROB I N | 2003 | Journal of ClinicalMicrobiology American Society for Microbiology2003，41，1： | 1 |
| 15 | Classical swine fever virus diversity and evolution 显示文摘 | Paul L Georgina I Jennifer N | 1996 | J Gen Virol1996，77，6： | 1 |
| 16 | Cnllaborative Production Planning of Supply Chain Under Price and De- mand Uncertainty显示文摘 | Guoquan Zhang Jennifer Shang Wenli l i | 2011 | European Journal of Operational Re- search2011，77，3： | 1 |
| 17 | Efficient optimization of crystallization conditions by manipulation of drop volume ratio and temperature 显示文摘 | JOSEPH R LUFT JENNIFER R WOLFLEY MERIEM I SAID | 2007 | Protein Sci2007，16，4： | 1 |
| 18 | Seroprevalence of humanpapillomavirus types 6,11,16 and 18 in Chinese women显示文摘 | Jia J Jennifer SS He Wang et a I | 2012 | BMC InfectDis2012，12，1： | 1 |
| 19 | Herbicide effect on growth and seed production of Lolium multiflorum in At- lantic Canada显示文摘 | JERRY A I JENNIFER L KEVIN V M | 2002 | Crop Protection2002，21，10： | 1 |
| 20 | Corporate Social Responsibility as a Strategic Shield Against Costs of Earnings Management Practices 显示文摘 | Mart i nez-Ferrero Jennifer Banerjee | 2016 | Journal of Business Ethics2016，33，2： | 1 |
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