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| 1 | Origin and accumulation of high-maturity oil and gas in deep parts of the Baxian Depression, Bohai Bay Basin, China显示文摘Great quantities of light oil and gas are produced from deep buried hill reservoirs at depths of 5,641 m to 6,027 m and 190 °C to 201 °C in the Niudong-1 Well, representing the deepest and hottest commercial hydrocarbons discovered in the Bohai Bay Basin in eastern China. This discovery suggests favorable exploration prospects for the deep parts of the basin. However, the discovery raises questions regarding the genesis and accumulation of hydrocarbons in deep reservoirs. Based on the geochemical features of the hydrocarbons and characteristics of the source rocks as well as thermal simulation experiments of hydrocarbon generation, we conclude that the oil and gas were generated from the highly mature Sha-4 Member (Es4 ) source rocks instead of thermal cracking of crude oils in earlier accumulations. The source kitchen with abnormal pressures and karsted carbonate reservoirs control the formation of high-maturity hydrocarbon accumulations in the buried hills (i.e., Niudong-1) in conjunction with several structural-lithologic traps in the Es4 reservoirs since the deposition of the upper Minghuazhen Formation. This means the oil and gas exploration potential in the deep parts of the Baxian Depression is probably high. | Zhao Xianzheng Jin Qiang Jin Fengming Ma Peng Wang Quan Wang Jing Ren Chunling Xi Qiuling | 2013 | Petroleum Science2013，10，3： | 10 |
| 2 | Geological characteristics of shale rock system and shale oil exploration breakthrough in a lacustrine basin:A case study from the Paleogene 1st sub-member of Kong 2 Member in Cangdong sag,Bohai Bay Basin,China显示文摘A deep understanding of the basic geologic characteristics of the fine-grained shale layers in the Paleogene 1 st sub-member of Kong 2 Member(Ek_2~1) in Cangdong sag, Bohai Bay Basin, is achieved through observation of 140 m continuous cores and systematic analysis of over 1 000 core samples from two wells. Basic geological conditions for shale oil accumulation are proposed based on the unconventional geological theory of oil and gas. The shale rock system mainly developed interbedded formation of felsic shale, calcareous and dolomitic shale and carbonates; high quality hydrocarbon source rock formed in the stable and closed environment is the material base for shale oil enrichment; intergranular pores in analcite, intercrystalline pores in dolomite and interlayer micro-fractures make tight carbonate, calcareous and dolomitic shale and felsic shale effective reservoirs, with brittle mineral content of more than 70%; high abundance laminated shale rock in the lower section of Ek_2~1 is rich in shale oil, with a total thickness of 70 m, burial depth between 2 800 to 4 200 m, an average oil saturation of 50%, a sweet spot area of 260 km^2 and predicted resources of over 5×10~8 t. Therefore, this area is a key replacement domain for oil exploration in the Kongdian Formation of the Cangdong sag. At present, the KN9 vertical well has a daily oil production of 29.6 t after fracturing with a 2 mm choke. A breakthrough of continental shale oil exploration in a lacustrine basin is expected to be achieved by volume fracturing in horizontal wells. | ZHAO Xianzheng ZHOU Lihong PU Xiugang JIN Fengming HAN Wenzhong XIAO Dunqing CHEN Shiyue SHI Zhannan ZHANG Wei YANG Fei | 2018 | Petroleum Exploration and Development2018，45，3： | 8 |
| 3 | Theories,technologies and practices of lacustrine shale oil exploration and development:A case study of Paleogene Kongdian Formation in Cangdong sag,Bohai Bay Basin,China显示文摘As the main factors affecting stable and high production and the production regularity of lacustrine shale oil are unclear,the theoretical understandings,key exploration and development technologies,development effect and production regularity of lacustrine shale oil have been analyzed and summarized based on 700 m cores taken systematically from Paleogene Kong 2 Member of 4 wells in Cangdong sag,over 100000 analysis data and formation testing data.Three theoretical understandings on shale oil enrichment and high production have been reached:(1)High-quality shale with“three highs and one low”is the material base for shale oil enrichment.(2)Medium-slightly high thermal evolution degree is the favorable condition for shale oil enrichment.(3)Laminar felsic shale is the optimal shale layer for oil enrichment in semi-deep lake facies.Key exploration and development technologies such as shale oil enrichment layer and area evaluation and prediction,horizontal well pattern layout,shale oil reservoir fracturing,optimization of shale oil production regime have been established to support high and stable shale oil production.Under the guidance of these theoretical understandings and technologies,shale oil in Cangdong sag has achieved high and stable production,and 4 of them had the highest production of over 100 tons a day during formation testing.In particular,Well GY5-1-1 L had a daily oil production of 208 m^(3).By April,2022,the 28 wells combined have a stable oil production of 300–350 tons a day,and have produced 17.8×10^(4) t of oil cumulatively.It is found that the shale oil production of horizontal well declines exponentially in natural flow stage,and declines in step pattern and then tends stable in the artificial lift stage.Proportion of light hydrocarbons in produced shale oil is in positive correlation with daily oil production and decreases regularly during production test. | ZHAO Xianzheng ZHOU Lihong PU Xiugang JIN Fengming HAN Wenzhong SHI Zhannan CHEN Changwei JIANG Wenya GUAN Quansheng XU Jing LIU Xuewei ZHANG Wei MA Jianying | 2022 | Petroleum Exploration and Development2022，49，3： | 4 |
| 4 | Hydrocarbon accumulation principles in troughs within faulted depressions and their significance in exploration显示文摘以前,在指责的消沉通常是的大陆人的马槽为烃累积看作了烃产生和逐出的一个地区而非一个地区。如果他们被证实是来源厨房,他们能组成潜在的戏的可能性将在随后的探索程序被俯看。在过去的几年里基于 Jizhong 消沉和 Erlian 盆的烃探索实践,这份报纸讨论水库分发被多重因素控制, lithological 累积是更可能的在马槽区域形成的新理解。在马槽区域控制大 lithological 烃累积的形成进一步记录三个主要因素。纸也讨论新概念结构并且 lithological 累积不仅共存而且补充对方。我们建议那个扇子三角洲在轻轻的斜坡上的马槽,三角洲前面和 sublacustrine 扇子的转换陡峭的斜坡上的前面,沿着差错陡坡的脚趾的隧道沙是为新油的发现的有利地点累积。这个概念的申请在 Jizhong 消沉和 Erlian 盆在马槽区域在地方导致了油的几百百万公吨的发现。 | Zhao Xianzheng Jin Fengming Wang Quan Lu Xuejun | 2011 | Petroleum Science2011，8，1： | 4 |
| 5 | Geological characteristics and key exploration technologies of continental shale oil sweet spots: A case study of Member 2 of Kongdian Formation in the Cangdong sag in the Huanghua depression, Bohai Bay Basin显示文摘Under the general trend of stepping-up oil and gas exploration and development in China,the unconventional oil and gas resources such as shale oil and gas have become an important alternative.Abundant continental shale oil resources are developed in Member 2 of Kongdian Formation(Ek2)of the Cangdong sag in the Huanghua depression of the Bohai Bay Basin which has complex structure,strong heterogeneity,and large buried depth,thus,the geological characteristic of shale oil accumulation and key exploration technologies are investigated on base of the system coring of 635.8 m,centimeter-level fine description and analysis of over ten thousand samples,therefore,the“four accurate”technologies have been developed,including the accurate selection of sweet spot areas,accurate drilling of sweet spot layers,accurate fracturing of sweet spot layers and accurate measure of fracture-rich sections.The results show that the continental shale strata in Member 2 of Kongdian Formation can be divided into three types:felsic shale,limy dolomitic shale and mixed shale.The Member 2 of Kongdian Formation is characterized by diverse mineral components,abundant laminae,good source rocks and medium thermal evolution degree,tight reservoir with rich micropore and microfractures,high oil saturation and brittle mineral content,indicating good prospect of shale oil exploration.Through sedimentological study,TOC and Ro evaluation,brittle mineral calculation,and seismic fusion inversion,a total of 126 km^(2) of Class I sweet spots in Member 2 of Kongdian Formation was delineated comprehensively,which guides horizontal well deployment(Well GD1701H and Well GD1702H).The drilling rate of sweet spot of these two horizontal wells is up to 96%by tracing thin layer through fine calibration,locating compartment through fine inversion,ensuring window entry through precise positioning,and tracking sweet spot through adjustment.The “one-excellent and five-highs”criterion is used to select perforation points to realize differential designs of fracturing intervals and clusters.Micro-seismic and potentiometry monitoring show that the artificial fractures formed by volumetric fracturing are 300e400 m long and 120 m high,and control a volume of about 0.07 km^(3).The maximum daily oil production of two horizontal wells is 48 t and 66 t respectively to realize the economic exploitation of shale oil reserves controlled by fractures.The shale oil exploration in Member 2 of Kongdian Formation shows that the continental shale oil has great potential of exploration and development,and the above technologies are critical and effective for shale oil efficient recovery. | Xianzheng Zhao Xiugang Pu Fengming Jin Wenzhong Han Zhannan Shi Aibing Cai Aiguo Wang Quansheng Guan Wenya Jiang Wei Zhang | 2019 | Petroleum Research2019，4，2： | 2 |
| 6 | The trend in newly diagnosed Crohn’s disease and extraintestinal manifestations of Crohn’s disease in central China: a retrospective study of a single center显示文摘 | Fengming Yi Min Chen Meifang Huang Jin Li Junzhang Zhao Lixia Li Bing Xia | 2012 | European Journal of Gastroenterology & Hepatology2012，，12： | 1 |
| 7 | A Novel Anti-Human Syndecan-1 (CD138) Monoclonal Antibody 4B3: Characterization and Application显示文摘Syndecan-1 (CD138), a member of integral membrane heparin sulfate proteoglycans, is an essential matrix receptor for maintaining the normal morphological phenotypes. In this study, we generated a specific mouse anti-human syndecan-1 monoclonal antibody (mAb) 4B3 and identified it by competition assay with the available syndecan-1 mAb (BB4). Stained by 4B3, the expression of syndecan-1 was detected on tumor cell lines, such as 8226, U266, XG-1, XG-2, Daudi and Jurkat. The expression was also found on neuron stem cells. It was established that 4B3 mAb could inhibit XG-1 and XG-2 proliferation. The data not only determined that 4B3 mAb was a functional anti-human syndecan-1 mAb, but also indicated that syndecan-1 might be a valuable surface antigen and play an important role in regulation of tumor pathology and differentiation of neural stem cells. This novel antibody 4B3 may be value of study of tumor proliferation/survival mechanism and contributes to diagnosis and treatment of diverse diseases. | Wanping Sun Fengming Wang Fang Xie Guoqing Wang Jin Sun Gehua Yu Yuhua Qiu Xueguang Zhang | 2007 | Cellular & Molecular Immunology2007，4，3： | 1 |
| 8 | Orally administered BZL-s RNA-20 oligonucleotide targeting TLR4 effectively ameliorates acute lung injury in mice显示文摘The global COVID-19 pandemic emerged at the end of December 2019.Acute respiratory distress syndrome(ARDS)and acute lung injury(ALI)are common lethal outcomes of bacterial lipopolysaccharide(LPS),avian influenza virus,and SARS-Co V-2.Toll-like receptor 4(TLR4)is a key target in the pathological pathway of ARDS and ALI.Previous studies have reported that herbal small RNAs(s RNAs)are a functional medical component.BZL-s RNA-20(Accession number:B59471456;Family ID:F2201.Q001979.B11)is a potent inhibitor of Toll-like receptor 4(TLR4)and pro-inflammatory cytokines.Furthermore,BZLs RNA-20 reduces intracellular levels of cytokines induced by lipoteichoic acid(LTA)and polyinosinic-polycytidylic acid(poly(I:C)).We found that BZL-s RNA-20 rescued the viability of cells infected with avian influenza H5N1,SARS-Co V-2,and several of its variants of concern(VOCs).Acute lung injury induced by LPS and SARS-Co V-2 in mice was significantly ameliorated by the oral medical decoctosome mimic(bencaosome;sphinganine(d22:0)+BZL-s RNA-20).Our findings suggest that BZLs RNA-20 could be a pan-anti-ARDS/ALI drug. | Dandan Zhao Yuhao Qin Jiaqi Liu Kegong Tang Shuaiyao Lu Zirui Liu Yexuan Lin Cong Zhang Fengming Huang Jiahui Chang Chang Li Mingyao Tian Yiming Ma Xiaoyun Li Congzhao Zhou Xiao Li Xiaozhong Peng Ningyi Jin Chengyu Jiang | 2023 | Science China(Life Sciences)2023，66，7： | 1 |
| 9 | On graphs determining links with maximal number of components via medial construction显示文摘 | Xian’an Jin Fengming Dong Eng Guan Tay | 2009 | Discrete Applied Mathematics2009，，14： | 1 |
| 10 | Characteristics of the Cretaceous Magmatism in Huanghua Depression and Their Relationships with Hydrocarbon Enrichment显示文摘The Huanghua depression located in the hinterland of the Bohai Bay Basin in eastern China is a typical area for the research of multistage magmatic activities with hydrocarbon enrichment,many high-yield wells related to igneous rocks were discovered within the Cretaceous strata in recent years.However,the spatial and temporal distribution of Cretaceous igneous rocks remains unclear,and the relationships among magmatic sequence,lithology,and hydrocarbon enrichment have been poorly studied.In order to solve these problems,core observation,logging analysis,major element analysis,zircon U-Pb chronology,oil-bearing grade statistics and reservoir spaces analysis were used to subdivide the magmatism cycles and to investigate the characteristics of igneous reservoirs.Our results show that the Mesozoic magmatism in Huanghua depression started in 140.1±1.4 Ma and could be divided into two stages including the Early Cretaceous stage and Late Cretaceous stage.The Early Cretaceous magmatism principally developed basic-intermediate rocks in the north zone,and could be subdivided into 3 cycles with their forming ages of 140,125–119,and 118–111 Ma,respectively.By contrast,the late stage mainly developed intermediate-acid rocks centralized in the south zone and formed at 75–70 Ma.The GR and SP curves are good indicators for the contrast of different lithologies,lithofacies and for magmatic sequences division.Intensive magmatism may have an advantage to form reservoirs,since basalt in cycle III in the Early Cretaceous and dacite porphyrite in the Late Cretaceous have great exploration potential.Lithology and tectonic fractures have an important influence on the formation of reservoir spaces and hydrocarbon enrichment.The characteristics of Cretaceous magmatism and igneous reservoirs in Huanghua depression and adjacent areas are summarized,providing important information for igneous reservoirs research and oil-gas exploration in the Cretaceous in related areas. | Fengming Jin Jian Huang Xiugang Pu Changqian Ma Lixin Fu Chongbiao Leng Da Lou Mutian Qin | 2020 | Journal of Earth Science2020，31，6： | 1 |
| 11 | Susceptibility behaviour and specific heat anomaly in single crystals of alanine and valine显示文摘 | Wenqing Wang Xiangrong Sheng Haofang Jin Jilan Wu Bo Yin Jingwei Li Zhongxian Zhao Hongshun Yang Fengming Lou Zhizhong Zhuang Guanyuan Yu Lei Shi Zhaojia Chen | 1996 | Journal of Biological Physics1996，，2： | 1 |
| 12 | Sweet spot evaluation and exploration practice of lacustrine shale oil of the second member of Kongdian Formation in Cangdong sag, Bohai Bay Basin显示文摘Based on core,thin section,X-ray diffraction,rock pyrolysis,CT scanning,nuclear magnetic resonance and oil testing data,the macro and micro components,sedimentary structure characteristics,of Paleogene Kong 2 Member in Cangdong sag of Huanghua depression and evaluation standard and method of shale oil reservoir were studied to sort out the best shale sections for shale oil horizontal wells.According to the dominant rock type,rhythmic structure and logging curve characteristics,four types of shale lithofacies were identified,namely,thin-layered dolomitic shale,lamellar mixed shale,lamellar felsic shale,and bedded dolomitic shale,and the Kong 21 sub-member was divided into four quasi-sequences,PS1 to PS4.The PS1 shale has a porosity higher than 6%,clay content of less than 20%,and S1 of less than 4 mg/g;the PS2 shale has well-developed laminar structure,larger pore and throat size,better connectivity of pores and throats,high contents of TOC and movable hydrocarbon,S1 of over 4 mg/g,clay content of less than 20%,and porosity of more than 4%;PS3 shale has S1 value higher than 6 mg/g and clay content of 20%-30%,and porosity of less than 4%;and PS4 shale has lower TOC content and low oil content.Shale oil reservoir classification criterion based on five parameters,free hydrocarbon content S1,shale rhythmic structure,clay content,TOC and porosity,was established.The evaluation method of shale oil sweet spot by using the weighted five parameters,and the evaluation index EI were proposed.Through comprehensive analysis,it is concluded that PS2 is best in quality and thus the dual geological and engineering sweet spot of shale oil,PS3 and PS1 come next,the former is more geologic sweet spot,the latter more engineering sweet spot,and PS4 is the poorest.Several vertical and horizontal wells drilled in the PS2 and PS3 sweet spots obtained high oil production.Among them,Well 1701 H has produced stably for 623 days,with cumulative production of over 10000 tons,showing bright exploration prospects of Kong 2 Member shale oil. | HAN Wenzhong ZHAO Xianzheng JIN Fengming PU Xiugang CHEN Shiyue MU Liangang ZHANG Wei SHI Zhannan WANG Hu | 2021 | Petroleum Exploration and Development2021，48，4： | 1 |
| 13 | Quantitative evaluation of lateral sealing of extensional fault by an integral mathematical-geological model显示文摘To evaluate the lateral sealing mechanism of extensional fault based on the pressure difference between fault and reservoir, an integral mathematical-geological model of diagenetic time on diagenetic pressure considering the influence of diagenetic time on the diagenetic pressure and diagenetic degree of fault rock has been established to quantitatively calculate the lateral sealing ability of extensional fault. By calculating the time integral of the vertical stress and horizontal in-situ stress on the fault rock and surrounding rock, the burial depth of the surrounding rock with the same clay content and diagenesis degree as the target fault rock was worked out. In combination with the statistical correlation of clay content, burial depth and displacement pressure of rock in the study area, the displacement pressure of target fault rock was calculated quantitatively. The calculated displacement pressure was compared with that of the target reservoir to quantitatively evaluate lateral sealing state and ability of the extensional fault. The method presented in this work was used to evaluate the sealing of F_(1), F_(2) and F_(3) faults in No.1 structure of Nanpu Sag, and the results were compared with those from fault-reservoir displacement pressure differential methods without considering the diagenetic time and simple considering the diagenetic time. It is found that the results calculated by the integral mathematical-geological model are the closest to the actual underground situation, the errors between the hydrocarbon column height predicted by this method and the actual column height were 0–8 m only, proving that this model is more feasible and credible. | LYU Yanfang HU Xinlei JIN Fengming XIAO Dunqing LUO Jiazhi PU Xiugang JIANG Wenya DONG Xiongying | 2021 | Petroleum Exploration and Development2021，48，3： | 0 |
| 14 | Formation of the primary petroleum reservoir in Wumaying inner buried-hill of Huanghua Depression, Bohai Bay Basin, China显示文摘Well Yinggu 1 drilled on the tectonic belt of the Wumaying buried-hill in Huanghua Depression obtained non-H2S high-yield oil and gas flow from the Permian Lower Shihezi Formation sandstone. The oil and gas are derived from the Upper Paleozoic coal source rock, the petroleum reservoir is an inner buried-hill primary oil and gas accumulation, showing a good prospect of the Paleozoic inner buried-hill primary reservoir exploration. The formation and accumulation of the primary petroleum reservoir in the Wumaying inner buried-hill are discussed by studying the primary source conditions, the inner buried-hill reservoir-cap combinations and the hydrocarbon accumulation period. The primary petroleum reservoir has three preponderant characteristics of accumulation: secondary large-scale gas generation of coal source rock, multi reservoir-cap combinations and mainly late hydrocarbon charging, which formed the compound hydrocarbon accumulation of the above-source sandstone and under-source carbonate rock in the Paleozoic inner buried-hill. Along with the Mesozoic and Cenozoic tectonic activities, the formation of the primary reservoir in Wumaying inner buried-hill is characterized by 'mixed oil and gas charge in local parts in early stage, adjustment accumulation due to structural high migration in middle stage, and large-scale natural gas charge and compound accumulation in late stage'. | JIN Fengming WANG Xin LI Hongjun WU Xuesong FU Lixin LOU Da ZHANG Jinning FENG Jianyuan | 2019 | Petroleum Exploration and Development2019，46，3： | 0 |
| 15 | Cycles of fine-grained sedimentation and their influences on organic matter distribution in the second member of Paleogene Kongdian Formation in Cangdong Sag,Bohai Bay Basin,East China显示文摘According to the theory of sequence stratigraphy based on continental transgressive-regressive(T-R)cycles,a 500 m continuous core taken from the second member of Kongdian Formation(Kong 2 Member)of Paleogene in Well G108-8 in the Cangdong Sag,Bohai Bay Basin,was tested and analyzed to clarify the high-frequency cycles of deep-water fine-grained sedimentary rocks in lacustrine basins.A logging vectorgraph in red pattern was plotted,and then a sequence stratigraphic framework with five-order high-frequency cycles was formed for the fine-grained sedimentary rocks in the Kong 2 Member.The high-frequency cycles of fine-grained sedimentary rocks were characterized by using different methods and at different scales.It is found that the fifth-order T cycles record a high content of terrigenous clastic minerals,a low paleosalinity,a relatively humid paleoclimate and a high density of laminae,while the fifth-order R cycles display a high content of carbonate minerals,a high paleosalinity,a dry paleoclimate and a low density of laminae.The changes in high-frequency cycles controlled the abundance and type of organic matter.The T cycles exhibit relatively high TOC and abundant endogenous organic matters in water in addition to terrigenous organic matters,implying a high primary productivity of lake for the generation and enrichment of shale oil. | ZHAO Xianzheng PU Xiugang YAN Jihua JIN Fengming SHI Zhannan CHAI Gongquan HAN Wenzhong LIU Yan JIANG Wenya CHEN Changwei ZHANG Wei FANG Zheng XIE Delu | 2023 | Petroleum Exploration and Development2023，50，3： | 0 |
| 16 | An exploration breakthrough in Paleozoic petroleum system of Huanghua Depression in Dagang Oilfield and its significance, North China显示文摘In recent years, several wells in the Qibei and Wumaying buried hills of Dagang Oilfield tapped oil in the Carboniferous–Permian and Ordovician strata. This major breakthrough reveals that the deep Paleozoic in the Bohai Bay is a new petroleum system. Through re-evaluating the Paleozoic source rock, reservoir-cap combinations and traps, it is found the oil and gas mainly come from Carboniferous–Permian source rock. The study shows that the Paleozoic strata are well preserved in the central-south Huanghua Depression and developed two kinds of reservoirs, Upper Paleozoic clastic rock and Lower Paleozoic carbonate rock, which form favorable source-reservoir assemblages with Carboniferous–Permian coal measure source rock. The Carboniferous–Permian coal-bearing source rock is rich in organic matters, which are mainly composed of type Ⅱ2 and Ⅲ kerogens, and minor Ⅱ1 kerogen in partial areas. Multi-stage tectonic movements resulted in two stages of hydrocarbon generation of the source rocks. The period from the deposition of Kongdian Formation to now is the second stage of hydrocarbon generation. The matching between large-scale oil and gas charging, favorable reservoir-cap combinations and stable structure determines the enrichment of oil and gas. According to the new comprehensive evaluation of Paleozoic petroleum system, the primary oil and gas resources of the Paleozoic in the Bohai Bay Basin are over 1×1012m3. The exploration breakthrough in Paleozoic petroleum system, especially Carboniferous–Permian petroleum system in Huanghua Depression is inspirational for oil and gas exploration in similar provinces of Bohai Bay Basin. | ZHAO Xianzheng PU Xiugang JIANG Wenya ZHOU Lihong JIN Fengming XIAO Dunqing FU Lixin LI Hongjun | 2019 | Petroleum Exploration and Development2019，46，4： | 0 |
| 17 | Development and exploration practice of the concept of hydrocarbon accumulation in rifted-basin troughs: A case study of Paleogene Kongdian Formation in Cangdong sag, Bohai Bay Basin显示文摘Based on the merged 3 D seismic data, well logging, formation testing, analysis and testing data, the structural evolution, sedimentary reservoirs, thermal evolution of source rocks were investigated of Paleogene Kongdian Formation in the trough area of Cangdong sag, Bohai Bay Basin. A conventional-unconventional hydrocarbon accumulation pattern in the trough area of rifted basin was revealed. The reservoir forming elements in the trough area of Cangdong sag have a zonation feature in terms of reservoirs and source rocks. There are two types of reservoir forming models, primary trough and reformed trough. The formation and evolution of trough controlled the orderly distribution of conventional oil to unconventional oil in the trough. Particularly, structural reservoirs occur in the upper part of the trough, stratigraphic-lithologic reservoirs are likely to form in the delta front deposits at the outer ring of trough, the middle ring transitional belt is the favorable site for tight oil reservoirs, while the fine grain deposits zone in the inner ring is shale oil and gas exploration area. The study has pointed out the new domains and directions for searching reserves in the secondary exploration of mature oilfields. | ZHAO Xianzheng ZHOU Lihong PU Xiugang JIN Fengming JIANG Wenya XIAO Dunqing HAN Wenzhong | 2018 | Petroleum Exploration and Development2018，45，6： | 0 |
| 18 | Avian influenza viruses suppress innate immunity by inducingtrans-transcriptional readthrough via SSU72显示文摘Innate immunity plays critical antiviral roles. The highly virulent avian influenza viruses (AIVs) H5N1, H7N9, and H5N6 can betterescape host innate immune responses than the less virulent seasonal H1N1 virus. Here, we report a mechanism by whichtranscriptional readthrough (TRT)-mediated suppression of innate immunity occurs post AIV infection. By using cell lines, mouselungs, and patient PBMCs, we showed that genes on the complementary strand (“trans” genes) influenced by TRT were involved inthe disruption of host antiviral responses during AIV infection. The trans-TRT enhanced viral lethality, and TRT abolishmentincreased cell viability and STAT1/2 expression. The viral NS1 protein directly bound to SSU72, and degradation of SSU72 inducedTRT. SSU72 overexpression reduced TRT and alleviated mouse lung injury. Our results suggest that AIVs infection induce TRT byreducing SSU72 expression, thereby impairing host immune responses, a molecular mechanism acting through the NS1-SSU72-trans-TRT-STAT1/2 axis. Thus, restoration of SSU72 expression might be a potential strategy for preventing AIV pandemics. | Yan Zhao Fengming Huang Zhen Zou Yuhai Bi Yang Yang Cong Zhang Qiang Liu Daozhen Shang Yiwu Yan Xiangwu Ju Song Mei Peng Xie Xiao Li Mingyao Tian Shuguang Tan Huijun Lu Zongsheng Han Kangtai Liu Yuqing Zhang Junbo Liang Zhu Liang Qingchao Zhang Jiahui Chang William JLiu Cong Feng Tanshi Li Michael Q.Zhang Xiaoyue Wang George FGao Yingxia Liu Ningyi Jin Chengyu Jiang | 2022 | Cellular & Molecular Immunology2022，19，6： | 0 |
| 19 | To Search, To Innovate, and To Climb显示文摘Jin Fengming has spent the past 34 years since he started his career working in the frontline of petroleum exploration geology research.He has completed more than 30 scientific research projects in Huabei Oilfield and Dagang Oilfield,either as the chief researcher or in cooperation with others;he also participated in more than 100 scientific research projects as the technical advisor,and engaged in the discovery of dozens of oil and gas fields(reservoirs)including that of Zhaozhouqiao,Baorao,Qibei Qianshan,Chenghai Duanpo,and Cangdong continental shale oil field,etc.,contributing more than 600 million tons of newly discovered oil geological reserves in total. | Jin Fengming | 2020 | China Oil & Gas2020，27，4： | 0 |
| 20 | Formation mechanisms of good-quality clastic reservoirs in deep formations in rifted basins:A case study of Raoyang sag in Bohai Bay Basin,East China显示文摘In order to reveal the development mechanism of high-quality clastic rock reservoir, the basic characteristics of Sha-3 Member of the Shahejie Formation in the Raoyang sag, Bohai Bay Basin, are analyzed based on cores observation, thin-sections and SEM images, and petrophysical properties measurements as well. It is found that high-mature composition and texture, early oil charging, and dissolution are the main factors controlling the formation and preservation of pores in deep reservoirs. Compaction is the major factor destructing pores, whereas formation overpressure is conducive to the preservation of original pores, high compositional and medium textural maturity can enhance the resistance capacity to compaction and protect primary pores. Early oil charging could lead to temporary cessation of diagenesis and thus inhibit the cementation. When organic acids entered reservoir formations, considerable amounts of secondary pores were formed, leading to the local improvement of petrophysical properties. When predicting good quality belt in exploration of deep basin, it is recommended that the superimposing effects of the multiple factors(overpressure, early oil charging, compositional and textural maturity, diagenesis) be taken into consideration. | JIN Fengming ZHANG Kaixun WANG Quan NIU Xinjie YU Zuogang BAI Guoping ZHAO Xuan | 2018 | Petroleum Exploration and Development2018，45，2： | 0 |
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