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| 1 | Cytokines,cytokine gene polymorphisms and Helicobacter pylori infection:Friend or foe?显示文摘Helicobacter pylori(H.pylori)is a flagellated,spiralshaped,microaerophilic Gram-negative bacillus that colonises the gastric mucosa of more than 50%of the human population.Infection is a risk factor for gastritis,ulcer disease and stomach cancer.Immunity against H.pylori is mainly related to Th1/Th17 skewing,and the activation of regulatory T cells is the main strategy used to limit inflammatory responses,which can result in the pathogen persistence and can lead to chronic gastrointestinal diseases,including cancer.Furthermore,host genetic factors that affect cytokines may determine differences in the susceptibility to many diseases.In this review,we present the cytokine profiles and the main cytokine gene polymorphisms associated with resistance/susceptibility to H.pylori and discuss how such polymorphisms may influence infection/disease outcomes. | Camila A Figueiredo Cintia Rodrigues Marques Ryan dos Santos Costa Hugo Bernardino F da Silva Neuza M Alcantara-Neves | 2014 | World Journal of Gastroenterology2014，20，18： | 11 |
| 2 | Response reduction factor of irregular RC buildings in Kathmandu valley显示文摘Most current seismic design includes the nonlinear response of a structure through a response reduction factor(R). This allows the designer to use a linear elastic force-based approach while accounting for nonlinear behavior and deformation limits. In fact, the response reduction factor is used in modern seismic codes to scale down the elastic response of a structure. This study focuses on estimating the actual ‘R' value for engineered design/construction of reinforced concrete(RC) buildings in Kathmandu valley. The ductility and overstrength of representative RC buildings in Kathmandu are investigated. Nonlinear pushover analysis was performed on structural models in order to evaluate the seismic performance of buildings. Twelve representative engineered irregular buildings with a variety of characteristics located in the Kathmandu valley were selected and studied. Furthermore, the effects of overstrength on the ductility factor, beam column capacity ratio on the building ductility, and load path on the response reduction factor, are examined. Finally, the results are further analyzed and compared with different structural parameters of the buildings. | Hemchandra Chaulagain Hugo Rodrigues Enrico Spacone Ramesh Guragain Radhakrishna Mallik Humberto Varum | 2014 | Earthquake Engineering and Engineering Vibration2014，13，3： | 2 |
| 3 | Comparative efficiency analysis of different nonlinear modelling strategies to simulate the biaxial response of RC columns显示文摘The performance of different nonlinear modelling strategies to simulate the response of RC columns subjected to axial load combined with cyclic biaxial horizontal loading is compared. The models studied are classified into two categories according to the nonlinearity distribution assumed in the elements: lumped-plasticity and distributed inelasticity. For this study, results of tests on 24 columns subjected to cyclic uniaxial and biaxial lateral displacements were numerically reproduced. The analyses show that the global envelope response is satisfactorily represented with the three modelling strategies, but significant differences were found in the strength degradation for higher drift demands and energy dissipation. | Hugo Rodrigues Humberto Varum António Arêde Aníbal Costa | 2012 | Earthquake Engineering and Engineering Vibration2012，11，4： | 2 |
| 4 | The use of lidocaine as an anti-inflammatory substance: A systematic review显示文摘 | Hugo Cesar Pinto Marques Caracas José Vinícius Bolognesi Maciel Patrícia Machado Rodrigues e Silva Martins Margareth Maria Gomes de Souza Lucianne Cople Maia | 2008 | Journal of Dentistry2008，，2： | 1 |
| 5 | The effect of furazolidone on the physico-chemical properties of dimyristoylphosphatidylcholine bilayers: Relevance to anti-leishmanial therapy显示文摘 | Victor Hugo Giendruczak Martins Marisa Raquel Rodrigues Layoan Dantas Mascarenhas Carla Roberta Lopes de Azambuja Julian Londo?o Londo?o Vania Rodrigues de Lima | 2014 | Journal of Molecular Structure2014，，： | 1 |
| 6 | Numerical modelling of the cyclic behaviour of RC elements built with plain reinforcing bars显示文摘 | José Melo Catarina Fernandes Humberto Varum Hugo Rodrigues Aníbal Costa António Arêde | 2010 | Engineering Structures2010，，2： | 1 |
| 7 | Performance of masonry enclosure walls:lessons learned from recent earthquakes显示文摘这份报纸为石工技术包围和填入墙讨论表演要求和构造标准的问题。在欧洲国家的垂直大楼围场被 non-load-bearing 石工技术墙很经常组成,用水平地穿孔的泥土砖。这些墙被柱和横梁 / 平板的增强的具体框架结构通常支持并且限制。因为这些墙通常被认为是 nonstructural 元素,他们对结构的反应的影响被忽略,他们在象他们到邻近的结构的元素的连接一样的结构的设计的考虑经常玩忽或不足地详细说明。作为后果,至于墙围场,当大楼受到地震行动时, nonstructural 元素对飘移和加速要求相对敏感。许多国际标准和技术文件为 nonstructural 元素为设计可接受程度标准强调需要,然而,他们明确地不显示怎么阻止倒塌并且严重裂开,并且怎么在情况中提高全面稳定性对高地震的装载中等。而且,适当措施的评论被探讨在地震行动下面改进包围墙性能和在里面飞机和 out-of-plane 正直。 | Romeu Silva Vicente Hugo Rodrigues Humberto Varum Aníbal Costa Jos António Raimundo Mendes da Silva | 2012 | Earthquake Engineering and Engineering Vibration2012，11，1： | 1 |
| 8 | Evaluation of the stress‐inducible production of proline in transgenic sugarcane (Saccharum spp.): osmotic adjustment, chlorophyll fluorescence and oxidative stress显示文摘 | Hugo Bruno CorreaMolinari Celso JamilMarur EdelclaitonDaros Marília Kaphan FreitasDe Campos Jane Fiuza Rodrigues PortelaDe Carvalho Jo?o Carlos BespalhokFilho Luiz Filipe ProtasioPereira Luiz Gonzaga EstevesVieira | 2007 | Physiologia Plantarum2007，，2： | 1 |
| 9 | Numerical modelling of the cyclic behaviour of RC elements built with plain reinforcing bars显示文摘 | José Melo Catarina Fernandes Humberto Varum Hugo Rodrigues Aníbal Costa António Arêde | 2010 | Engineering Structures2010，，2： | 1 |
| 10 | The network of P‐glycoprotein and microRNAs interactions显示文摘 | Vanessa Lopes‐Rodrigues Hugo Seca Diana Sousa Emília Sousa Raquel T. Lima M. Helena Vasconcelos | 2014 | Int J Cancer2014，，2： | 1 |
| 11 | Seismic fragility assessment of revised MRT buildings considering typical construction changes显示文摘The present study investigates the vulnerability assessment of the prototype revised Mandatory Rule of Thumb(MRT)buildings initially designed and detailed for three storeys bare frame building;later modified through variable number of storeys(three,four,and five)and different arrangement of infill walls(bare frame,soft-storey,irregular infilled,and fully infilled).The application of infill walls increases the fundamental frequencies,stiffness,and maximum strength capacity,but reduces the deformation capability than the bare frame building.The vulnerability was also reduced through infill walls,where the probability of exceeding partial-collapse and collapse damage reduced by 80% and 50%,respectively.Furthermore,the increased in storeys(three to five)also increases the failure probability,such that partial-collapse and collapse for fully infilled increases by almost 55% and 80%,respectively.All obtained results and discussions concluded that the structural sections and details assigned for MRT building is not sufficient if considered as bare frame and soft-storey.And increase in number of storeys causes building highly vulnerable although the infill walls were considered. | Rakesh DUMARU Hugo RODRIGUES Humberto VARUM | 2020 | Frontiers of Structural and Civil Engineering2020，14，1： | 0 |
| 12 | Structural Health Monitoring of Different Geometry Structures With Optical Fiber Sensors显示文摘在这份报纸,我们描述几结构监视的结构的健康,与不同几何学,材料和行为,用光纤维传感器。那些研究试图处于监视的结构的健康表明如此的技术的可行性,与对光纤维技术固有的所有优点。 | Paulo ANTUNES Hugo RODRIGUES Rui TRAVANCA Licinio FERREIRA Humberto VARUM Paulo ANDRE | 2012 | Photonic Sensors2012，2，4： | 0 |
| 13 | Mechanical properties characterization of different types of masonry infill walls显示文摘It is remarkable,the recent advances concerning the development of numerical modeling frameworks to simulate the infill panels'seismic behavior.However,there is a lack of experimental data of their mechanical properties,which are of full importance to calibrate the numerical models.The primary objective of this paper is to present an extensive experimental campaign of mechanical characterization tests of infill masonry walls made with three different types of masonry units:lightweight vertical hollow concrete blocks and hollow clay bricks.Four different types of experimental tests were carried out,namely:compression strength tests,diagonal tensile strength tests,and flexural strength tests parallel and perpendicular to the horizontal bed joints.A total amount of 80 tests were carried out and are reported in the present paper.The second objective of this study was to compare the mechanical properties of as-built and existing infill walls.The results presented and discussed herein,will be in terms of strain-stress curves and damages observed within the tests.It was observed a fragile behavior in the panels made with hollow clay horizontal bricks,without propagation of cracks.The plaster increased the flexural strength by 57%. | Andre FURTADO Hugo RODRIGUES Antonio AREDE Humberto VARUM | 2020 | Frontiers of Structural and Civil Engineering2020，14，2： | 0 |
| 14 | A methodology for coffee price forecasting based on extreme learning machines显示文摘This work introduces a methodology to estimate coffee prices based on the use of Extreme Learning Machines.The process is initiated by identifying the presence of nonstationary components,like seasonality and trend.These components are withdrawn if they are found.Next,the temporal lags are selected based on the response of the Partial Autocorre-lation Function filter.As predictors,we address the following models:Exponential Smooth-ing(ES),Autoregressive(AR)and Autoregressive Integrated and Moving Average(ARIMA)models,Multilayer Perceptron(MLP)and Extreme Learning Machines(ELMs)neural net-works.The computational results based on three error metrics and two coffee types(Ara-bica and Robusta)showed that the neural networks,especially the ELM,can reach higher performance levels than the other models.The methodology,which presents preprocess-ing stages,lag selection,and use of ELM,is a novelty that contributes to the coffee prices forecasting field. | Carolina Deina Matheus Henrique do Amaral Prates Carlos Henrique Rodrigues Alves Marcella Scoczynski Ribeiro Martins Flavio Trojan Sergio Luiz Stevan Jr Hugo Valadares Siqueira | 2022 | Information Processing in Agriculture2022，9，4： | 0 |
| 15 | Seismic safety assessment of existing masonry infill structures in Nepal显示文摘Reinforced concrete(RC) buildings in Nepal are constructed with RC frames and masonry infill panels. These structures exhibit a highly non-linear inelastic behavior resulting from the interaction between the panels and frames. This paper presents an extensive case study of existing RC buildings in Nepal. Non-linear analyses were performed on structural models of the buildings considered as a bare frame and with masonry infill, in order to evaluate the influence of infill walls on the failure mechanisms. Five three-storey buildings with different structural configurations and detailing were selected. The effect of masonry infill panels on structural response was delineated by comparing the bare-framed response with the infill response. Seismic performance is evaluated with regard to global strength, stiffness, energy dissipation, inter-storey drift, and total deflection of the structure. A parametric analysis of structures with masonry infill is also performed. For this, the influence of different material properties is studied, namely diagonal compressive stress, modulus of elasticity and tensile stress of masonry infill panels. Study results show that masonry infill increases the global strength and stiffness of the structures; it decreases the inter-storey drift and hence the total displacement of the structure. The results quantify the influence of the infill panels on structural response and, in particular, the effect of the diagonal compressive strength of the masonry wall. | Hemchandra Chaulagain Hugo Rodrigues Enrico Spacone Humberto Varum | 2016 | Earthquake Engineering and Engineering Vibration2016，15，2： | 0 |
| 16 | Increasing Powers in a Degenerate Parabolic Logistic Equation显示文摘The purpose of this paper is to study the asymptotic behavior of the positive solutions of the problemt ■tu-△u=au-b(x)up inΩ×R+,u(0)=u0,u(t)|■Ω=0,as p → +∞,where Ω is a bounded domain,and b(x) is a nonnegative function.The authors deduce that the limiting configuration solves a parabolic obstacle problem,and afterwards fully describe its long time behavior. | Jos Francisco RODRIGUES Hugo TAVARES | 2013 | Chinese Annals of Mathematics,Series B2013，34，2： | 0 |
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