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| 1 | Elevated alanine aminotransferase activity is not associated with dyslipidemias,but related to insulin resistance and higher disease grades in non-diabetic non-alcoholic fatty liver disease显示文摘Objective:To explore demographic and metabolic factors associated with increased alanine aminotransferase(ALT)activity in non-diabetic non-alcoholic fatty liver disease(NAFLD)patients.Methods:Overall 372 patients who consecutively attended to Gastroenterology Clinic of Baqiyatallah University of Medical Sciences,Tehran,Iran awere diagnosed as NAFLD entered into analysis.Exclusion criteria were having diabetes mellitus and fasting blood glucose over126 mg/dL,active hepatitis B virus infection,having hepatitis C virus positive serology,and to be under corticosteroid therapy.ALT levels were considered pathologically high when it was over30 IU/L for men and over 19 IU/L for women.Results:Bivariate analyses using t test and chisquare test showed that patients with pathologically augmented ALT levels had significantly higher NAFLD grades in their ultrasonographic evaluations(P=0.003).Moreover,these patients represented significantly higher homeostatic model assessment levels(P=0.003),levels of serum insulin(P=0.002),fasting blood glucose(P<0.001),and uric acid(P=0.02).The prevalence of insulin resistance was also higher in patients with increased serum ALT concentrations.Multifactorial logistic regression models showed that ultrasonographic grading of NAFLD(P=0.027)and insulin resistance(P=0.013)were the only variables significantly associated with abnormal ALT levels.Conclusions:This study shows that the associations of increased ALT serum levels in NAFLD patients are different from what are supposed before.By excluding diabetic patients from our population,we find that increased ALT levels are not associated with dyslipidemias but are independently associated with insulin resistance and NAFLD grading on ultrasonographic evaluations.Further studies are needed to confirm our results. | Mohammad Ebrahim Ghamar-Chehreh Mohsen Amini Hossein Khedmat Seyed Moayed Alavian Fatemeh Daraei Reza Mohtashami Reza Hadi Bent-Al-Hoda Beyram Saeed Taheri | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，9： | 5 |
| 2 | Analytical study of care quality and moral distress in clinical situations and patient care显示文摘Objective: Nursing profession conventionally meets a high standard of ethical behavior and action. One of the ethical challenges in nursing profession is moral distress. Nurses frequently expose to this phenomenon which leads to different consequences such as being bored by delivering patient care that decline care quality and make it challenging to achieve health purposes. This study was conducted to investigate the association between the aspects of moral distress and care quality.Methods: In this descriptive–analytical study, 545 nurses of intensive and cardiac care units and dialysis and psychiatric wards were recruited by census sampling. Three questionnaires, Sociodemographics, Moral Distress Scale, and Quality Patient Care Scale, were distributed among the participants and collected within 9 months. Data analysis was conducted by descriptive statistics, analysis of variance, and the least significant difference in SPSS 13.Results: Investigating moral distress domains(ignoring patient, decision-making power, and professional competence) and care quality domains(psychosocial, physical, and communicational) demonstrated that in being exposed to moral distress, ignoring patient had no effect on psychosocial domain(P=0.056), but decision-making and professional competence of moral distress had positive effect on psychosocial, physical(bodily), and communication domains of care quality.Conclusions: Because moral distress domains are effective on patient care quality, it is recommended to enhance the knowledge of nurses, especially beginners, about moral distress, increase their strength alongside standardizing nursing services in decisionmaking domains, improve the professional competence, and pay attention to patients. | Masoumeh Hasanlo Arezo Azarm Parvaneh Asadi Kourosh Amini Hossein Ebrahimi Mohammad Asghari Jafarabadi | 2019 | Frontiers of Nursing2019，6，4： | 3 |
| 3 | Performance of IEEE 802.15.4 Clusters with Power Management and Key Exchange显示文摘IEEE 802.15.4 说明是最近的低数据率无线个人区域网络标准。当基本安全服务被提供时,有在现代个人区域网络应用程序不可缺少的更先进的技术的缺乏。另外,那些服务的表演含意不被知道。在这篇论文,我们基于 ZigBee 说明描述一个安全数据交换协议并且在 IEEE 802.15.4 连接层上造了。这个协议包括关键交换机制。我们假设所有节点基于察觉到协调人要求的可靠性的经常的事件正在使用电源管理技术。电源管理由相当在节点之中在一般水准散布察觉到的负担的每个节点产生随机的睡觉时间。关键交换被一个簇协调人在察觉到包被协调人收到了的某给定的数字以后开始。我们开发并且集成关键交换和电源管理技术的模拟模型进簇的可靠察觉到功能。我们在簇性能上评估安全功能和它的频率的影响。 | Fereshteh Amini Moazzam Khan Jelena Mii Hossein Pourreza | 2008 | Journal of Computer Science & Technology2008，23，3： | 2 |
| 4 | Hydrodynamic mechanisms of aggressive collapse events in leading edge cavitation显示文摘Transient cavities generated from unsteady leading-edge cavitation may undergo aggressive collapses which are responsible for cavitation erosion.In this paper,we studied the hydrodynamic mechanisms of these events in the leading edge cavitation fonned over a modified NACA0009 hydrofoil using experimental and numerical methods.In the experimental investigation,high-speed visualization(HSV)and paint test are employed to study the behavior of the cavitating flow at σ=1.25,α=5°,U∞=20 m/s.In the numerical part,the same cavitating flow is simulated using an inviscid density-based compressible solver with a barotropic cavitation model.The numerical results are first compared with the experimental HSV to show that the simulation is able to reproduce the main features of the cavitating flow.Then,as the compressible solver is capable of capturing the shock wave upon the collapse of cavities,the location of collapse events with high erosion potential are determined.The location of these collapse events are compared with the paint test results with a qualitatively good agreement.It is clearly observed,in both the experiments and the numerical simulation,that there exists four distinct regions along the hydrofoil with higher risks of erosion:(1)A very narrow strip at the leading edge,(2)an area of accumulated collapses at around 60 percent of the sheet cavity maximum length,(3)an area around the closure line of the sheet cavity with the highest erosion damage,and(4)a wide area close to the trailing edge with dispersed collapse events.A combined analysis of the experimental and numerical results reveals that the small-scale structures generated by secondary shedding are more aggressive than the large-scale cloud cavities(primary shedding).It is also observed that the high risk of cavitation erosion in regions 2 and 3 is mainly due to the collapses of the small cavity structures that are formed around the sheet cavity closure line or the rolling cloud cavity. | Mohammad Hossein Arabnejad Ali Amini Mohamed Farhat Rickard EBensow | 2020 | Journal of Hydrodynamics2020，32，1： | 2 |
| 5 | Numerical analysis and experimental validation of hydrodynamics of a thin bubbling fluidized bed for various particle-size distributions using a three-dimensional dense discrete phase model显示文摘A dense discrete phase model combined with the kinetic theory of granular flows was used to study the bubbling characteristics and segregation of poly-dispersed particle mixtures in a thin fluidized bed.Our simulations showed that in using the hybrid Eulerian-Lagrangian method,the common use of one computational cell in the thickness direction of the thin bed does not predict wall friction correctly.Instead,a three-cell discretization of the thickness direction does predict the wall friction well but six cells were needed to prevent overprediction of the bed expansion.The change in specularity factor(SF)of the model not only affected the predictions of the velocity of particles,but also had a considerable impact on their flow pattern.A decrease in SF,which decreases wall friction,showed an over-prediction in the size of bubbles,particle velocities,and void fraction of the bed,and led to a shift in the circulation center toward the bottom of the bed.The segregation of the Geldart B particles was studied in the narrow range from 400 to 600μm with a standard deviation less than 10%of the average diameter.Simulations showed that large particles accumulated close to the distributor at the bottom of the bed and the center of the bed,but small particles moved towards the wall and top surface.The decrease in the mean particle size and spread in shape of the distribution improves mixing by up to 30%at a superficial gas velocity of around 2.5 times the minimum fluidization velocity.Log-normal mixtures with a small proportion of large particles had the most uniform distribution with a thin layer of jetsam forming at the bottom of the bed.Finally,experimental verification of the segregation and mixing of polydisperse particles with narrow size distribution is suggested. | Abolhasan Hashemisohi Lijun Wang Abolghasem Shahbazi Hossein Amini | 2020 | Particuology2020，18，2： | 2 |
| 6 | Assessment of land suitability and agricultural production sustainability using a combined approach (Fuzzy-AHP-GIS):A case study of Mazandaran province,Iran显示文摘This research was conducted to evaluate the sustainability of rice production using fuzzy logic in Mazandaran province,Iran.The untapped use of modern agricultural technology,such as agricultural machinery,has become a global dilemma,which has forced governments and environmentalists to take a serious stand against the dangers of massive non-standard agricultural practices in the environment.Three types of mechanization,socioeconomic,and economic modeling were used to determine the sustainability and their values were collected through interview method using a 320-item questionnaire from 2016 to 2018.Land evaluation was carried out using soil and climate characteristics,so that about 27.4%of the area was in the perfectly suitable range(S1),35.2%in the appropriate range(S2),19.5%in the critical range(S3),and 17.9%in the inappropriate range(N)for rice cultivation.Farmers were selected from two regions(R1 and R2)by the GIS on two lower levels and more than one hectare(A1,A2)according to agricultural methods(mechanical and traditional).The results showed that the highest and lowest means of the product were 4314.44 and 3501.95 kg ha1,respectively.The sustainability of production was within the range of“sustainability”and“almost sustainable”in terms of mechanistic and economic factors in the fuzzy range of“moderate sustainability”and also with respect to social factors that are in a better position than mechanistic and economic indicators.Results of final sustainability model showed that the average of the lasting sustainability index was in the range of“almost unsustainable”and“moderate sustainability”. | Sherwin Amini Abbas Rohani Mohammad Hossein Aghkhani Mohammad Hossein Abbaspour-Fard Mohammad Reza Asgharipour | 2020 | Information Processing in Agriculture2020，7，3： | 1 |
| 7 | Determination of metformin in human plasma by high-performance liquid chromatography 显示文摘 | Hossein Amini Abolhassan Ahmadiani Parisa Gazerani | 2005 | Journal of Chromatography B2005，824，12： | 1 |
| 8 | Simple determination of cyclosporine in human whole blood by high-performance liquid chromatography显示文摘 | Hossein Amini Abolhassan Ahmadiani | 2003 | J Chromatogr B2003，，795： | 1 |
| 9 | How much will be the cost for universal coverage of COVID-19 vaccination and how shall it be financed?显示文摘Given the failure to find a definitive cure for COVID-19,the only hopes for controlling the pandemic right now are vaccine production and universal vaccination.Therefore,vaccine is vital to the prevention and control of COVID-19 outbreak and it will support global health security. | Mohammad Meskarpour-Amiri Hossein Amini Ali Mehrabi Tavana | 2021 | Asian Pacific Journal of Tropical Medicine2021，14，4： | 1 |
| 10 | Design,synthesis and pharmacological evaluation of 4-[2-alkylthio-5(4)-(4-substitutedphenyl)imidazole-4(5)yl]benzenesulfonamides as selective COX-2 inhibitors显示文摘目的: 设计并且综合一系列苯硫安类药剂衍生物, 4-[2-alkylthio-5 (4 )-(4-substitutedphenyl)imidazole-4(5)-yl]benzenesulfonamides(4a-4j),which 被打算与好 COX-2 禁止者活动作为 cyclooxygenase-2 (COX-2 ) 扮演禁止者,并且哪个愿望在 vivo.Methods 的 exertanti 煽动性的活动: Benzenesulfonamide 衍生物通过多步化学药品反应被设计并且综合。所有综合混合物被评估在一在里面 vitro 试金。活跃复合 4a-4f 在导致 acarrageenan 的老鼠爪浮肿 model.Results 为进一步的评估被选择: 停靠研究显示出 4 绑进 COX-2 的主要有约束力的地点,硫安类药剂 SO2NH2 一半与第二等的袖珍氨基酸残余交往的那混合物。在里面在里面 vitro 试金,有 1.23-8 nmol/L 的抑制集中 IC50 价值的化合物 4 禁止的 COX-2 ,与有 1.5nmol/L .Compound 的 IC50 价值的 celecoxib 相比, 4b 和 4c 与 celecoxib.In 相比有好力量和选择 invivo 模型,复合 4a-4f 展出了中等力量与 1.58-4.3 mg/kg.In 的价值禁止50% 导致carrageenan 的爪浮肿后者实验,复合 4c 是大多数 activecompound.Conclusion :煽动性的效果为复合 4a-4j 获得了的反能在这些混合物的苯基戒指的帕拉位置由于氟的符号或氢取代者的存在。 | Mona SALIMI Mohammad Hossein GHAHREMANI Nima NADERI Mohsen AMINI Elika SALIMI Massoud AMANLOU Khosrou ABDI Raha SALEHI Abbas SHAFIEE | 2007 | Acta Pharmacologica Sinica2007，28，8： | 0 |
| 11 | Outbreak of methanol-induced optic neuropathy in early COVID-19 era;effectiveness of erythropoietin and methylprednisolone therapy显示文摘BACKGROUND Methanol is a highly toxic,non-potable alcohol.Outbreaks of methanol toxicity occur due to its fraudulent addition to alcoholic beverages as a cheaper substitute for ethanol.Recently,alongside the coronavirus disease 2019(COVID-19)pandemic,rumors circulated on social media that consuming alcohol can prevent or cure the virus,leading to a COVID-19 and methanol-induced optic neuropathy(MON)syndemic.AIM To investigate the impact of erythropoietin(EPO)on the outcomes of patients diagnosed with MON.METHODS In this prospective study,105 patients presenting with acute bilateral visual loss secondary to methanol intoxication were enrolled from March to May 2020 at Farabi Eye Hospital.A comprehensive ocular examination was conducted for all participants.Recombinant human EPO and methylprednisolone were administered intravenously to all patients for three consecutive days.RESULTS The mean age of the participants was 39.9 years(±12.6).Ninety-four patients were male and eleven were female.The mean pre-treatment best corrected visual acuity(BCVA)improved from 2.0±0.86 to 1.39±0.69 logarithm of the minimum angle of resolution post-treatment(P<0.001),with significant improvement observed in all age categories and genders(P<0.001).Visual acuity improvement was also significant regardless of whether the patient presented before or after 72 h(P<0.001),and the post-treatment BCVA remained significant at all monthly follow-up visits(P<0.001).CONCLUSION EPO and methylprednisolone therapy have been shown to be effective in improving visual outcomes in patients with MON when administrated within the first month of exposure.Public awareness efforts are necessary to prevent further outbreaks of methanol toxicity in the current COVID-19 era. | Seyed Ali Tabatabaei Mohammad Amini Ali A Haydar Mohammad Soleimani Kasra Cheraqpour Mansoor Shahriari Hossein Hassanian-Moghaddam Nasim Zamani Mohammad Reza AkbariDepartment of Ophthalmology Eye Research Center Farabi Eye | 2023 | World Journal of Clinical Cases2023，11，15： | 0 |
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