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31篇 您的检索式：作者名="Honsova"

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	题名	作者	年代	出处	被引量
1	Epithelial markers of colorectal carcinogenesis in ulcerative colitis and primary sclerosing cholangitis显示文摘AIM:To evaluate the expression of epithelial markers of colorectal carcinogenesis in patients with long-term ulcerative colitis(UC) and primary sclerosing cholangitis(PSC) before and after transplantation.METHODS:Eight patients with UC and PSC prior to liver transplantation(PSC-UC),22 patients with UC after liver transplantation for PSC(OLT),9 patients with active ulcerative colitis without PSC(UCA),7 patients withUC in remission(UCR) and 10 controls(N) underwent colonoscopy with multiple biopsies.Specimens were analysed histologically and semi-quantitatively immunohistochemically for p53,Bcl-2 and cyclooxygenase-2(COX-2) markers.Statistical analysis was performed by Kruskal-Wallis and Fisher's exact tests.RESULTS:PSC-UC had a statistically significantly higher expression of p53 in the nondysplastic mucosa as compared to OLT,UCA,UCR and N(P < 0.05).We also found a statistically significant positive correlation between the incidence of PSC and the expression of p53(P < 0.001).UCA had a higher p53 expression as compared to UCR.OLT had a significantly lower expression of p53 as compared with PSC-UC(P < 0.001).Bcl-2 had a significant higher bcl-2 expression as compared with controls.No difference in COX-2 expression between PSC-UC,UCR and UCA was found.UCA had higher COX-2 expression as compared to UCR.We also found a statistically significant positive correlation between the expression of COX-2 and p53.Patients after liver transplantation for PSC had a statistically significantly lower expression of the p53 compared with PSCUC(P < 0.001).PSC-UC had the same inflammatory endoscopic activity as OLT and UCR when evaluated with the Mayo score.CONCLUSION:Our study shows that the nondysplatic mucosa of UC patients with PSC is characterised by a higher expression of the tumour suppressor gene p53,suggesting a higher susceptibility of cancer.This p53 overexpression correlates with the presence of PSC whilst it is not present in patients with UC after liver transplantation for PSC.	Pavel Wohl Tomas Hucl Pavel Drastich David Kamenar Julius Spicak Eva Honsova Eva Sticova Alena Lodererova Jan Matous Martin Hill Petr Wohl Milos Kucera	2013	World Journal of Gastroenterology2013，19，14：	2
2	Kidney biopsy is a sensitive tool for retrospective diagnosis of PLA2R- related membranous nephropathy显示文摘	Svobodova B Honsova E Ronco P	2013	Nephrol Dial Transplant2013，28，7：	1
3	Association of advanced vaseulopathy and transforming growth factor-beta1 gene expres- sion with immunoglobulin A nephropathy progression显示文摘	Brabeova I Tesar V Honsova E	2011	Neph- rol Dial Transplant2011，26，2：	1
4	Interleukin 18 ( IL-18) upregulation in acute rejection of kidney allograft显示文摘	Striz I Krasna E Honsova E	2005	Immunol Lett2005，99，1：	1
5	Kidney biopsy is a sensitive tool for retrospective diagnosis of PLA2R-related membranous nephropathy显示文摘	Svobodova B Honsova E Konco P	2013	Nephrol Dial Transplant2013，28，7：	1
6	Clinical relevance of antibodies to HLA antigens undetectable by the standard complement-dependent cytotoxicity test显示文摘	Slavcev A Lacha J Honsova E	2003	Transpl Int2003，16，12：	1
7	Association of advanced vasculopathy and transforming growth factor-betal gene expression with immunoglobulin A nephropathy progression 显示文摘	Brabcova I Tesar V Honsova E	2011	Nephrol Dial Transplant2011，26，2：	1
8	Number of serotonin positive cells and acute cellular rejection in the early period after small bowel transplantation in pigs显示文摘	HONSOVA E LODEREROVA A BALAZ P		0，，01：	1
9	Kidney biopsy is asensitive tool for retrospective diagnosis of PLA2R-relatedmembranous nephropathy显示文摘	Svobodova B Honsova E Roneo P	2013	Nephrol Dial Transplant2013，28，7：	1
10	Secondary membranous nephropathy-one center experience 显示文摘	Rihova Z Honsova E Merta M et at	2005	Ren Fail2005，27，4：	1
11	Molecular patterns of subclinical and clinical rejection of kidney allograft:quantity matters 显示文摘	Wohlfahrtova M Tycova 1 Honsova E	2015	Kidney Blood Press Res2015，40，3：	1
12	Plasmapheresis and intravenous immunoglobulin in early antibody-mediated rejection of the renal allograft:a single-center experience显示文摘	Slatinska J Honsova E Burgelova M	2009	TherApher Dial2009，13，2：	1
13	Interleukia 18 ( IL - 18 ) upregulation in acute rejection of kidney allogra显示文摘	Il ja Striz Krasna Eliska Honsova Eva	2005	Immunology Letters2005，99，：	1
14	Clinical relevance of antibodies to HLA antigens undetectable by the standard complement-dependent cytotoxicity test显示文摘	Slavcer A Lacha J Honsova E		0，，12：	1
15	Kidney bi- opsy is a sensitive tool for retrospective diagnosis of PLA2R- related membranous nephropathy 显示文摘	SVOBODOVA B HONSOVA E RONCO P	2013	Nephrol Dial Trans- plant2013，28，：	1
16	Interleuk in 18(IL - 18) upregulation in acute rejection of kidney allograft 显示文摘	Striz I K rasna E Honsova E	2005	ImmunolLett2005，99，1：	1
17	Histopathological differential diagnosis of pri- mary liver tumors显示文摘	Honsova E	2014	Rozhl Chir2014，93，3：	1
18	Association of advanced vas- culopathy and transforming growth factor-betal gene expression with immunoglobulin A nephropathy progression 显示文摘	Brabcova I Tesar V Honsova E	2011	Nephvol Dial Trans- plant2011，26，2：	1
19	Association of advanced vasculopathy and transforming growth factor-betal gene expression with immunoglobulin A nephropathy progression显示文摘	Brabcova I Tesar V Honsova E		0，，02：	1
20	Kidney biopsy is a sensitive tool for retrospective diagnosis of PLA2R-related membranous nephropathy显示文摘	Svobodova B Honsova E Ronco P	2013	Nephrol Dial Transplant2013，28，7：	1

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