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4篇 您的检索式:作者名="Hitoshi Kusaba"
    题名 作者 年代 出处 被引量
1Metastatic basaloid-squamous cell carcinoma of the esophagus treated by 5-fluorouracil and cisplatin显示文摘Basaloid squamous cell carcinoma (BSC) of the esophagus is a rare malignant disease. We report here a patient with recurrent esophageal BSC,who was successfully treated by systemic chemotherapy containing 5-fluorouracil (5-FU) and cisplatin (CDDP). A 57-year-old woman was diagnosed as having squamous cell carcinoma of the esophagus upon endoscopic examination. Curative esophagectomy with lymph node dissection was performed under the thoracoscope. The pathological diagnosis of the surgical specimen was BSC. Five months after operation,the patient was diagnosed as having a recurrence of the BSC with metastases to the liver and spleen,and a right paraclavicular lymph node. She was given systemic chemotherapy consisting of continuous infusion of 800 mg/d of 5-FU and 3 h infusion of 20 mg/d of CDDP for 5 consecutive days every 4 wk. The metastatic lesions in the spleen and right paraclavicular lymph node disappeared,and the liver metastasis was apparently reduced in size after 2 courses of chemotherapy. The tumor regression was seen over 6 courses,with progression afterwards. Although subsequent treatment with CPT-11 and CDDP was not effective,docetaxel and vinorelbine temporarily controlled the tumor growth for 2 mo. 5-FU and CDDP combination may be useful for the patients with advanced BSC.Yoshihiro Shibata Eishi Baba Hiroshi Ariyama Ryusuke Miki Nobumichi Ogami Shuji Arita Baoli Qin Hitoshi Kusaba Kenji Mitsugi Hirokazu Noshiro Takashi Yao Shuji Nakano 2007World Journal of Gastroenterology2007,13,26:9
2In vitro sequence-dependent interaction between nedaplatin and paclitaxel in human cancer cell lines显示文摘Risa Tanaka Yasushi Takii Yoshihiro Shibata Hiroshi Ariyama Baoli Qin Eishi Baba Hitoshi Kusaba Kenji Mitsugi Mine Harada Shuji Nakano 2005Cancer Chemotherapy and Pharmacology2005,,3:1
3Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cells显示文摘Keita Uchino Gen Hirano Minako Hirahashi Taichi Isobe Tsuyoshi Shirakawa Hitoshi Kusaba Eishi Baba Masazumi Tsuneyoshi Koichi Akashi 2012Experimental Cell Research2012,,15:1
4Activated Src and Ras induce gefitinib resistance by activation of signaling pathways downstream of epidermal growth factor receptor in human gallbladder adenocarcinoma cells显示文摘Baoli Qin Hiroshi Ariyama Eishi Baba Risa Tanaka Hitoshi Kusaba Mine Harada Shuji Nakano 2006Cancer Chemotherapy and Pharmacology2006,,5:1
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